PKC gamma 抗体 (C-Term)
Quick Overview for PKC gamma 抗体 (C-Term) (ABIN1108733)
抗原
See all PKC gamma (PRKCG) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects PRKCG (C-term).
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Immunogen affinity purified
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免疫原
- Synthetic peptide corresponding to a sequence at the C-terminal of human PKC gamma .Remarks: Sequence is identical to the related rat and mouse sequence.
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亚型
- IgG
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anti-Protein Kinase C, gamma (PRKCG) (pThr514) antibody
PRKCG 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) (AA 260-351) antibodyPRKCG 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) (Internal Region) antibodyPRKCG 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) (Thr655) antibodyPRKCG 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) (AA 1-314) antibodyPRKCG 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) (AA 71-120) antibodyPRKCG 适用: 人, 大鼠, 小鼠, Cow, 兔, 犬, 豚鼠, 马, 猴, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) (AA 539-588) antibodyPRKCG 适用: 人, 大鼠, 小鼠, Cow, 兔, 犬, 豚鼠, 马, 猴, 斑马鱼, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) (N-Term) antibodyPRKCG 适用: 人 WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) (N-Term) antibodyPRKCG 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) (AA 665-685), (C-Term) antibodyPRKCG 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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缓冲液
- 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
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储存液
- Sodium azide, Thimerosal (Merthiolate)
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注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- PKC gamma (PRKCG) (Protein Kinase C, gamma (PRKCG))
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别名
- PRKCG
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背景
- The gamma isotype of protein kinase C (PKC gamma) is a member of the classical PKC (cPKC) subfamily which is activated by Ca(2+) and diacylglycerol in the presence of phosphatidylserine. Physiologically, PKC gamma is activated by a mechanism coupled with receptor-mediated breakdown of inositol phospholipid as other cPKC isotypes such as PKC alpha and PKC beta. PKC gamma is expressed solely in the brain and spinal cord and its localization is restricted to neurons, while PKC alpha and PKC beta are expressed in many tissues in addition to the brain. Within the brain, PKC gamma is the most abundant in the cerebellum, hippocampus and cerebral cortex, where the existence of neuronal plasticity has been demonstrated. PKC gamma gene is mutated in spinocerebellar ataxia type 14 (SCA14). Verbeek et al. (2005) point out the specific alterations in mutant PKC gamma function that could lead to the selective neuronal degeneration of SCA14.Synonyms: PKC gamma, PKC-gamma, PKCC, PKCG, Protein kinase C gamma type
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基因ID
- 5582
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NCBI登录号
- NP_002730
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UniProt
- P05129
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途径
- WNT signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGF Signaling
抗原
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