(2 references)-
- 抗原 See all PKC gamma (PRKCG) 抗体
- PKC gamma (PRKCG) (Protein Kinase C, gamma (PRKCG))
-
抗原表位
- AA 665-685, C-Term
-
适用
- 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This PKC gamma antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Protein kinase C gamma type(PRKCG) detection. Tested with WB in Human,Mouse,Rat.
- 序列
- IDQADFQGFT YVNPDFVHPD A
- 交叉反应 （详细）
-
Predicted Cross Reactivity: human, mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
-
Rabbit IgG polyclonal antibody for Protein kinase C gamma type(PRKCG) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: protein kinase C, gamma
Protein Name: Protein kinase C gamma type(PKC-gamma) - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human PKC gamma(665-685aa IDQADFQGFTYVNPDFVHPDA), identical to the related rat and mouse sequences.
- 亚型
- IgG
- Top Product
- Discover our top product PRKCG Primary Antibody
-
anti-Protein Kinase C, gamma (PRKCG) (C-Term) antibody
PRKCG 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) (pThr514) antibodyPRKCG 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) (AA 260-351) antibodyPRKCG 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) (AA 150-250) antibody (PerCP)PRKCG 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal PerCP
anti-Protein Kinase C, gamma (PRKCG) (AA 150-250) antibody (Atto 488)PRKCG 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal Atto 488
anti-Protein Kinase C, gamma (PRKCG) (AA 150-250) antibody (Atto 594)PRKCG 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal Atto 594
anti-Protein Kinase C, gamma (PRKCG) (AA 150-250) antibody (Atto 390)PRKCG 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal Atto 390
anti-Protein Kinase C, gamma (PRKCG) antibodyPRKCG 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, gamma (PRKCG) (AA 499-697) antibodyPRKCG 适用: 人 WB, ELISA, IP, ICC 宿主: 小鼠 Monoclonal M110 unconjugated
anti-Protein Kinase C, gamma (PRKCG) (Internal Region) antibodyPRKCG 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human, Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
-
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
-
-
: "5-(Bis(3-(2-hydroxyethyl)-1H-indol-2-yl)methyl)-2-hydroxybenzoic acid (BHIMHA): showing a strategy of designing drug to block lung metastasis of tumors." in: Drug design, development and therapy, Vol. 10, pp. 711-21, (2016) (PubMed).
: "Extracts from Salvia-Nelumbinis naturalis alleviate hepatosteatosis via improving hepatic insulin sensitivity." in: Journal of translational medicine, Vol. 12, pp. 236, (2015) (PubMed).
-
: "5-(Bis(3-(2-hydroxyethyl)-1H-indol-2-yl)methyl)-2-hydroxybenzoic acid (BHIMHA): showing a strategy of designing drug to block lung metastasis of tumors." in: Drug design, development and therapy, Vol. 10, pp. 711-21, (2016) (PubMed).
-
- 抗原
- PKC gamma (PRKCG) (Protein Kinase C, gamma (PRKCG))
- 别名
- PRKCG (PRKCG 产品)
- 别名
- PRKCG antibody, PKC-gamma antibody, PKCC antibody, PKCG antibody, SCA14 antibody, PKCgamma antibody, Pkcc antibody, Prkcc antibody, PKC antibody, PKCI antibody, Prkc antibody, RATPKCI antibody, protein kinase C gamma antibody, protein kinase C, gamma antibody, protein kinase C gamma type antibody, PRKCG antibody, Prkcg antibody, LOC484316 antibody
- 背景
-
The gamma isotype of protein kinase C(PKC gamma) is a member of the classical PKC(cPKC) subfamily which is activated by Ca(2+) and diacylglycerol in the presence of phosphatidylserine. Physiologically, PKC gamma is activated by a mechanism coupled with receptor-mediated breakdown of inositol phospholipid as other cPKC isotypes such as PKC alpha and PKC beta. PKC gamma is expressed solely in the brain and spinal cord and its localization is restricted to neurons, while PKC alpha and PKC beta are expressed in many tissues in addition to the brain. Within the brain, PKC gamma is the most abundant in the cerebellum, hippocampus and cerebral cortex, where the existence of neuronal plasticity has been demonstrated. PKC gamma gene is mutated in spinocerebellar ataxia type 14(SCA14). Verbeek et al.(2005) point out the specific alterations in mutant PKC gamma function that could lead to the selective neuronal degeneration of SCA14.
Synonyms: KPCG_HUMAN antibody|MGC57564 antibody|OTTHUMP00000067291 antibody|PKC-gamma antibody|PKCC antibody|PKCG antibody|PRKCG antibody|Protein kinase C gamma antibody|Protein kinase C gamma polypeptide antibody|Protein kinase C gamma type antibody|Protein kinase C, gamma antibody|SCA 14 antibody|SCA14 antibody - UniProt
- P05129
- 途径
- WNT signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGF Signaling
-
You are here:
