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Ly6g 抗体 (Biotin)

The 大鼠 单克隆 anti-Ly6g antibody is suitable to detect Ly6g in samples from 小鼠. It has been validated for IHC (fro), IHC (p), Func 和 EIA.
产品编号 ABIN1108439
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Ly6g 抗体 (Biotin) (ABIN1108439)

抗原

Ly6g (Lymphocyte Antigen 6 Complex, Locus G (Ly6g))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

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This Ly6g antibody is conjugated to Biotin

应用范围

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Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Functional Studies (Func), Enzyme Immunoassay (EIA)

克隆位点

NIMP-R14
  • 交叉反应 (详细)

    Species reactivity (tested):Mouse.

    纯化方法

    Protein G

    免疫原

    Purified BALB/c mouse neutrophils

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.02 % Sodium Azide, 0.1 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2 - 8 °C.
  • 抗原

    Ly6g (Lymphocyte Antigen 6 Complex, Locus G (Ly6g))

    别名

    Ly6G / GR1 Neutrophil Marker

    背景

    The Ly-6G/-6C locus encodes a family of Ly-6 proteins including Ly-6G and Ly-6C. Ly-6 antigens have a molecular weight between 15,000 and 18,000. Ly6G is together with Ly6c a component of the myeloid differentiation antigen Gr-1. Ly6G a GPI-anchored protein and is a good marker of peripheral neutrophils. Although predominantly presents on neutrophils, it is also expressed on a subset of eosinophils, differentiating pre-monocytes and plasmacytoid dendritic cells. Ly6C is a monocyte/macrophage and endothelial cell differentiation antigen regulated by interferon gamma, and may play a role in the development and maturation of lymphocytes. It is expressed on bone marrow cells, monocytes/macrophages, neutrophils, endothelial cells, and T cell subsets. Expression of Gr-1 in bone marrow correlates with granulocyte differentiation and maturation. However, the physiological role of Ly6G alone remains still unclear.Synonyms: Gr-1 Granulocyte marker

    基因ID

    10090

    UniProt

    P35461
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