Ly6g 抗体
(9 references)Quick Overview for Ly6g 抗体 (ABIN1108437)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应 （详细）
- Species reactivity (tested):Mouse.
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纯化方法
- Protein G Chromatography
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免疫原
- Purified BALB/c Mouse Neutrophils
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亚型
- IgG2b
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anti-Lymphocyte Antigen 6 Complex, Locus G (Ly6g) antibody
Ly6g 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte Antigen 6 Complex, Locus G (Ly6g) antibodyLy6g 适用: 小鼠 FACS, WB, IP, IHC (fro), IHC (p), Func 宿主: 大鼠 Monoclonal RB6-8C5 unconjugated
anti-Lymphocyte Antigen 6 Complex, Locus G (Ly6g) antibodyLy6g 适用: 小鼠, 大鼠 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte Antigen 6 Complex, Locus G (Ly6g) antibody (PE-Cy7)Ly6g 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal RB6-8C5 PE-Cy7
anti-Lymphocyte Antigen 6 Complex, Locus G (Ly6g) antibody (FITC)Ly6g 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal 1A8 FITC
anti-Lymphocyte Antigen 6 Complex, Locus G (Ly6g) antibodyLy6g 适用: 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte Antigen 6 Complex, Locus G (Ly6g) antibody (Biotin)Ly6g 适用: 小鼠 FACS, WB, IP, IHC (fro), IHC (p) 宿主: 大鼠 Monoclonal RB6-8C5 Biotin
anti-Lymphocyte Antigen 6 Complex, Locus G (Ly6g) antibody (violetFluor™ 450)Ly6g 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal RB6-8C5 violetFluor™ 450
anti-Lymphocyte Antigen 6 Complex, Locus G (Ly6g) antibody (violetFluor™ 450)Ly6g 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal 1A8 violetFluor™ 450
anti-Lymphocyte Antigen 6 Complex, Locus G (Ly6g) antibody (APC)Ly6g 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal 1A8 APC
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA
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储存条件
- 4 °C
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储存方法
- Store undiluted at 2-8 °C.
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: "Innate immune-induced depletion of bone marrow neutrophils aggravates systemic bacterial infections." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 17, pp. 7107-12, (2009) (PubMed).
: "Absence of cross-reactivity between murine Ly-6C and Ly-6G." in: Cytometry. Part A : the journal of the International Society for Analytical Cytology, Vol. 58, Issue 2, pp. 195-200, (2004) (PubMed).
: "Complement factor C5a mediates renal ischemia-reperfusion injury independent from neutrophils." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 7, pp. 3883-9, (2003) (PubMed).
: "An immunomodulatory function for neutrophils during the induction of a CD4+ Th2 response in BALB/c mice infected with Leishmania major." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 5, pp. 2628-36, (2000) (PubMed).
: "Adenoviral vector-mediated overexpression of IL-4 in the knee joint of mice with collagen-induced arthritis prevents cartilage destruction." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 8, pp. 4546-56, (1999) (PubMed).
: "Monocytes/macrophages rather than PMN are involved in early cartilage degradation in cationic immune complex arthritis in mice." in: Journal of leukocyte biology, Vol. 61, Issue 3, pp. 267-78, (1997) (PubMed).
: "Sequence of a cDNA specifying subunit VIIa of human cytochrome c oxidase." in: Nucleic acids research, Vol. 17, Issue 17, pp. 7107, (1989) (PubMed).
: "Schistosoma mansoni: evidence that immunity in vaccinated and chronically infected CBA/Ca mice is sensitive to treatment with a monoclonal antibody that depletes cutaneous effector cells." in: Parasite immunology, Vol. 9, Issue 6, pp. 667-82, (1988) (PubMed).
: "Differentiation antigens on mouse eosinophils and neutrophils identified by monoclonal antibodies." in: British journal of haematology, Vol. 57, Issue 3, pp. 489-94, (1984) (PubMed).
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: "Innate immune-induced depletion of bone marrow neutrophils aggravates systemic bacterial infections." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 17, pp. 7107-12, (2009) (PubMed).
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- Ly6g (Lymphocyte Antigen 6 Complex, Locus G (Ly6g))
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别名
- Ly6G / GR1 Neutrophil Marker
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背景
- The Ly-6G/-6C locus encodes a family of Ly-6 proteins including Ly-6G and Ly-6C. Ly-6 antigens have a molecular weight between 15,000 and 18,000. Ly6G is together with Ly6c a component of the myeloid differentiation antigen Gr-1. Ly6G a GPI-anchored protein and is a good marker of peripheral neutrophils. Although predominantly presents on neutrophils, it is also expressed on a subset of eosinophils, differentiating pre-monocytes and plasmacytoid dendritic cells. Ly6C is a monocyte/macrophage and endothelial cell differentiation antigen regulated by interferon gamma, and may play a role in the development and maturation of lymphocytes. It is expressed on bone marrow cells, monocytes/macrophages, neutrophils, endothelial cells, and T cell subsets. Expression of Gr-1 in bone marrow correlates with granulocyte differentiation and maturation. However, the physiological role of Ly6G alone remains still unclear.Synonyms: Gr-1 Granulocyte marker
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基因ID
- 10090
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UniProt
- P35461
抗原
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