MUC5AC 抗体
Our Local Distributor
北京 101111
Quick Overview for MUC5AC 抗体 (ABIN1108320)
抗原
See all MUC5AC 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
交叉反应 (详细)
- Species reactivity (tested):Human.
-
纯化方法
- Purified
-
免疫原
- A BALB/c mouse was immunized with Mucin isolated from an ovarian cyst fluid (pure endocervical type according to the Fenoglio's classisfication). Splenocytes were fused with mouse myeloma SP2/0 cells.
-
亚型
- IgG1
-
-
-
-
应用备注
-
Immunohistochemistry on cultured cells. Immunochemistry on Frozen Ethanol Fixed Sections. Immunochemistry on Paraffin Sections: a protease pretreatment is recommended. This antibody clone 1-13M1 cross reacts with Mucin of different animal species after period date pretreatment. Immunoblotting: Strongly positive without mercaptoethanol pretreatment of mucin solution. ELISA or IRMA in combination with the clone 9-13M1 or the mixture of anti-M1 Monoclonal antibodies.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 0.1 mg/mL
-
缓冲液
- PBS, 0.05 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))
-
别名
- Mucin-5AC
-
背景
- Mucins are high molecular weight glycoproteins that are found especially in the secretions of mucus membranes. Gastric Mucin 5AC antigen is found in columnar mucus cells of surface gastric epithelium and in goblet cells of the fetal and precancerous colon but not in normal colon. Resurgence of gastric mucin during colonic carcinogenesis is suggestive of either re-expression of the peptide core of gastric mucin in the adult colon or due to changes in the glycosylation pattern of mucin, which expose the hidden Mucin 5AC antigen.Synonyms: Gastric mucin, LeB, Lewis B blood group antigen, MUC5, MUC5AC, Major airway glycoprotein, Mucin-5 subtype AC, TBM, Tracheobronchial mucin, tracheobronchial
-
基因ID
- 9606
-
UniProt
- P98088
抗原
-