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MAPT 抗体 (pThr181)

This anti-MAPT antibody is a 小鼠单克隆 antibody detecting MAPT in WB. Suitable for 人和小鼠.

Western Blotting (WB) image for anti-Microtubule-Associated Protein tau (MAPT) (AA 177-187), (pThr181) antibody (ABIN1108154) (MAPT 抗体 (pThr181))

1 image

产品编号 ABIN1108154

发货至: 中国

Quick Overview for MAPT 抗体 (pThr181) (ABIN1108154)

抗原

See all MAPT 抗体

MAPT (Microtubule-Associated Protein tau (MAPT))

适用

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119
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15
7
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人, 小鼠

宿主

小鼠

克隆类型

单克隆

标记

216
17
6
5
2
2
2
2
2
2
2
2
1
1
1

This MAPT antibody is un-conjugated

应用范围

218
141
90
39
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17
7
4
3
3
2
2
2
1
1

Western Blotting (WB)

克隆位点

9B4

Discover our top product MAPT Primary Antibody

抗原表位
12

9

8

7

7

7

7

7

7

6

6

6

6

6

6

5

4

4

4

4

4

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1
AA 177-187, pThr181

序列

Ala-Pro-Lys-Thr(p)-Pro-Pro-Ser-Ser-Gly-Glu-Cys

交叉反应（详细）

Species reactivity (tested):Human, mouse

纯化方法

Protein G affinity purified

免疫原

KLH conjugated with a short peptide corresponding to the amino acid sequence 177-187 on the phosphorylated Tau protein

亚型

IgG1
anti-Microtubule-Associated Protein tau (MAPT) (pThr212) antibody
MAPT 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (pSer262) antibody
MAPT 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (pSer235) antibody
MAPT 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (AA 130-386) antibody
MAPT 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (AA 34-368) antibody
MAPT 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (pThr181) antibody
MAPT 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (pThr205) antibody
MAPT 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (pSer404) antibody
MAPT 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (pSer422) antibody
MAPT 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein tau (MAPT) (pSer356) antibody
MAPT 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
溶解方式

Double distillated water is recommended to reconstitute the antibody.

缓冲液

0.01 M PBS pH 7.2

注意事项

Avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store at -20 °C.
抗原

MAPT (Microtubule-Associated Protein tau (MAPT))

别名

MAPT / tau

背景

Tau is a neuronal microtubule associated protein found predominantly on axons. The function of Tau is to promote tubulin polymerisation and stabilise microtubules, but it also serves to link certain signalling pathways to the cytoskeleton. Tau, in its hyperphosphorylated form, is the major component of paired helical filaments (PHF) and neurofibrillary lesions in Alzheimer's disease (AD) brain. Hyperphosphorylation impairs the microtubule binding function of Tau, resulting in the destabilisation of microtubules in AD brains, ultimately leading to the degeneration of the affected neurons. Hyperphosphorylated tau is also found in a range of other central nervous system disorders. Numerous serine/threonine kinases, including GSK3 beta, PKA, Cdk5, and casein kinase II can phosphorylate Tau.Synonyms: MAPTL, MTBT1, Microtubule-associated protein tau, Neurofibrillary tangle protein, PHF-tau, Paired helical filament-tau

基因ID

9606

UniProt

P10636

途径

MAPK Pathway, Microtubule Dynamics, M Phase, Regulation of Cell Size

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