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IL-8 抗体

This 兔 多克隆 antibody specifically detects IL-8 in WB, IP, Func 和 EIA. It exhibits reactivity toward 人 和 猴.
产品编号 ABIN1107877
发货至: 中国
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Quick Overview for IL-8 抗体 (ABIN1107877)

抗原

See all IL-8 (IL8) 抗体
IL-8 (IL8) (Interleukin 8 (IL8))

适用

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人, 猴

宿主

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克隆类型

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多克隆

标记

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This IL-8 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Functional Studies (Func), Enzyme Immunoassay (EIA)
  • 特异性

    The antibody reacts with human natural and recombinant Interleukin-8 (IL-8) as assessed by ELISA. The antibody inhibits the biological activity of human native and recombinant IL-8. The antibody cross reacts with rhesus and cynomolgus natural IL-8.

    交叉反应 (详细)

    Species reactivity (tested):Human, Cynomolgus monkey, Rhesus monkey

    纯化方法

    Protein A

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2 - 8 °C.
  • 抗原

    IL-8 (IL8) (Interleukin 8 (IL8))

    别名

    Interleukin-8 / IL8

    背景

    Interleukin 8 (IL-8), formerly called monocyte-derived neutrophil chemotactic factor, belongs to the C-X-C chemokine family. IL-8 has 4 cysteine residues, as do other members of the chemokine family, and the first two cysteine residues are separated by glutamine. IL-8 consists of 72 amino acids with a molecular weight of 8,000 daltons. IL-8 exhibits chemotactic activity in vitro for T cells, basophils and neutrophils. IL-8 activates neutrophils to release lysosomal enzymes including myeloperoxidase, -mannosidase and -glucuronidase. IL-1 induces the production of IL-8 from fibroblasts, keratinocytes, endothelial cells, hepatoma cells, astrocytoma cells, glioblastoma cells, lung epithelial cells, synovial membrane cells, melanocytes, melanoma cells and gastric cancer cells. Lipopolysaccharides will stimulate IL-8 production in monocytes/macrophages, and expressed on endothelial cells in response to inflammation.Synonyms: CXCL8, Emoctakin, GCP1, Granulocyte chemotactic protein 1, MDNCF, MONAP, Monocyte-derived neutrophil chemotactic factor, Monocyte-derived neutrophil-activating peptide, NAP1, Neutrophil-activating protein 1, Protein 3-10C, T-cell chemotactic factor

    基因ID

    3576

    NCBI登录号

    NP_000575

    UniProt

    P10145

    途径

    TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagy
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