HLA-DMA 抗体
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Quick Overview for HLA-DMA 抗体 (ABIN1107564)
抗原
See all HLA-DMA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The antibody reacts with murine MHC class II glycoproteins. It recognizes a shared determinant on I-Ab, I-Ad, I-Aq, and I-Ed, I-Ek alloantigens, but it does not react with I-Af, I-Ak, I-As. This antibody can inhibit I-A-restricted T cell responses of the H-2b, H-2d, H-2q, H-2u but not H-2f, H-2k, H-2s haplotypes.
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交叉反应 （详细）
- Species reactivity (tested):Mouse
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纯化方法
- Protein-G affinity chromatography
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纯度
- > 95 % pure by SDS-PAGE
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免疫原
- Activated C57BL/6 mouse spleen cells
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亚型
- IgG2b
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anti-Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) (AA 1-261) antibody
HLA-DMA 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) (AA 1-261) antibodyHLA-DMA 适用: 人 ELISA, WB, IHC (p) 宿主: 小鼠 Monoclonal 3F12-F11 unconjugated
anti-Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) antibodyHLA-DMA 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) (AA 27-233) antibodyHLA-DMA 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) antibodyHLA-DMA 适用: 人, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) (AA 58-107) antibodyHLA-DMA 适用: 人, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) (AA 1-261) antibodyHLA-DMA 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Azide free phosphate buffered saline (PBS), approx. pH 7.4, 0.2 μm filter sterilized
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储存液
- Azide free
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- HLA-DMA (Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA))
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背景
- MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on the surface of professional antigen-presenting cells, such as macrophages, dendritic cells and B cells. Before their exposition on the cell surface, the MHC class II molecules react with endocytosed exogenous antigens, which are then presented to the T cells. The antigen-binding grove between MHC class II alpha and beta chain is open at both ends and is 15-24 amino acid residues long.Synonyms: DM alpha chain, DMA, HLA class II histocompatibility antigen, MHC class II antigen DMA, RING6, Really interesting new gene 6 protein
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基因ID
- 3108
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NCBI登录号
- NP_006111
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UniProt
- P28067
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途径
- Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
抗原
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