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Histone H2B 抗体

适用: 人, 小鼠, 大鼠, Hamster WB, IF, IP 宿主: 小鼠 Monoclonal C14264 unconjugated
产品编号 ABIN1107547
发货至: 中国
  • 抗原 See all Histone H2B 抗体
    Histone H2B
    适用
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    人, 小鼠, 大鼠, Hamster
    宿主
    • 209
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    小鼠
    克隆类型
    • 204
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    单克隆
    标记
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    This Histone H2B antibody is un-conjugated
    应用范围
    • 158
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    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat, hamster
    纯化方法
    Protein A agarose
    免疫原
    Protein fraction extracted from the mitotic chromosome
    克隆位点
    C14264
    亚型
    IgG2b
    Top Product
    Discover our top product Histone H2B Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 50 % glycerol, pH 7.2, without preservatives
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store (in aliquots) at -20 °C.
  • 抗原
    Histone H2B
    Abstract
    Histone H2B 产品
    别名
    Hist1h2bc antibody, H2B antibody, HISTONE H2B antibody, MRN17.11 antibody, MRN17_11 antibody, histone B2 antibody, H2B1 antibody, HIS2B antibody, histone cluster 1 H2B family member k antibody, histone H2B antibody, histone B2 antibody, histone H2B.3 antibody, Hist1h2bk antibody, H2B antibody, HTB2 antibody, THAPSDRAFT_27352 antibody, THAPSDRAFT_37309 antibody, THAPS_6947 antibody, THAPSDRAFT_34210 antibody, LOC426037 antibody, LOC107802329 antibody
    背景
    The nucleosome is made up of four core histone proteins (H2A, H2B, H3 and H4) and is the primary building block of chromatin. The N-terminal tail of core histones undergoes multiple different post-translational modifications including acetylation, phosphorylation, ubiquitination, methylation, and ADP-ribosylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. Acetylation of histone H2B was suppressed to greater extent than that of the others, with histone H3 being relatively least affected. The analysis of acetylation status of each of the four lysine sites at the N-terminal tail of histone H2B revealed decreases consistent with those observed in the total acetylation patterns, with the K12 and K20 residues being markedly more affected than K5 and K15 residues.Synonyms: H2B Histone Family, HIST1H2B
    分子量
    14 kDa
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