Histone H2B 抗体
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北京 101111
Quick Overview for Histone H2B 抗体 (ABIN7204986)
抗原
See all Histone H2B 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse Anti-Histone H2B Monoclonal Antibody
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特异性
- The antibody detects endogenous Histone H2B protein.
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纯化方法
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
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免疫原
- Synthetic Peptide
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亚型
- IgG1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:1000-3000,IF 1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.5 % BSA, 0.02 % sodium azide as Preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- Histone H2B
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背景
- HIST1H2BB, H2BFF, Histone H2B type 1-B, Histone H2B.1, Histone H2B.f, H2B/fHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. HIST1H2BB is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from HIST1H2BB lack polyA tails, instead, they contain a palindromic termination element. HIST1H2BB is found in the large histone gene cluster on chromosome 6p22-p21.3.
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分子量
- 14kD
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基因ID
- 3018
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UniProt
- P33778
抗原
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