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- 抗原 See all Fibrinogen 抗体
- Fibrinogen
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抗原表位
- citrullinated
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Fibrinogen antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 交叉反应 （详细）
- Species reactivity (tested):Human.
- 纯化方法
- Purified
- 克隆位点
- 3F2
- 亚型
- IgG2a
- Top Product
- Discover our top product Fibrinogen Primary Antibody
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anti-Fibrinogen antibody
适用: 人, 大鼠 ELISA, IHC (p), IF (p), IHC (fro), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Fibrinogen antibody (Biotin)适用: 人 ELISA, WB, IHC 宿主: 山羊 Polyclonal Biotin
anti-Fibrinogen antibody适用: 人 IHC (p), IF (p) 宿主: 小鼠 Monoclonal 4F7 unconjugated
anti-Fibrinogen antibody适用: 人 ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Fibrinogen antibody适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C2 unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL (when dissolved at 0.5 mg/mL, the BSA concentration will be 1%)
- 缓冲液
- 10 mM Ammonium Bicarbonate buffer
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C . Add 0.05% Sodium Azide for longer storage.
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- 抗原
- Fibrinogen
- Abstract
- Fibrinogen 产品
- 别名
- fib2 antibody, MGC53620 antibody, fibrinogen antibody, sb:cb892 antibody, wu:fa55c12 antibody, wu:fb20e08 antibody, wu:fb59b03 antibody, wu:fi39d04 antibody, zgc:92117 antibody, fibrinogen alpha chain antibody, fibrinogen gamma chain antibody, fga antibody, FGA antibody, LOC698244 antibody, CpipJ_CPIJ010090 antibody, FGG antibody
- 背景
- Fibrinogen is a protein produced by the liver which helps stop bleeding by helping blood clots to form. Fibrinogen gets deiminated (conversion from arginin to citrullin) by Peptidyl Arginine Deiminase (PAD) in inflamed joints in patients that develop rheumatoid arthritis.Citrulline, while being an amino acid, is not built into proteins during protein synthesis, as it is not coded for by DNA, yet several proteins are known to contain citrulline. These citrulline residues are generated by a family of enzymes called peptidylarginine deiminases (PADs), which convert arginine into citrulline in a process called citrullination or deimination. Proteins that normally contain citrulline residues include myelin basic protein (MBP), filaggrin, and several histone proteins, while other proteins, like fibrin and vimentin can get citrullinated during cell death and tissue inflammation. Patients with rheumatoid arthritis often (at least 80 % of them) develop an immune response against proteins containing citrulline. Although the origin of this immune response is not known, detection of antibodies reactive with citrulline containing proteins or peptides is now becoming an important help in the diagnosis of rheumatoid arthritis.Synonyms: FGA, FGB, FGG
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