(5 references)-
- 抗原 See all Fibrinogen 抗体
- Fibrinogen
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适用
- 小鼠
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This Fibrinogen antibody is un-conjugated
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应用范围
- Immunodiffusion (ID), Immunoelectrophoresis (IEP), Radial Immunodiffusion (RID)
- 特异性
- The antiserum does not cross-react with any other component of mouse plasma. Inter-species cross-reactivity is a normal feature of antibodies to plasma proteins since they frequently share antigenic determinants. of this antiserum has not been tested in detail.
- 产品特性
- Precipitating polyclonal goat antiserum to mouse fibrinogen
- 纯化方法
- Adsorption: Immunoaffinity adsorbed using insolubilized antigens as required, to eliminate antibodies cross-reacting with other with other serum proteins. The use of insolubilized adsorption antigens prevents the presence of excess adsorbent protein or immune complexes in the antiserum.
- 免疫原
- Fibrinogen (clotting factor I) is a heat labile beta glycoprotein present in plasma. It is the precursor of fibrin, which is the key protein constituting the network of the blood clot. Thrombin converts fibrinogen to fibrin by limited proteolysis. Fibrin monomers polymerize to fibrin which is stabilized by cross-linking. Fibrinogen is isolated from fresh plasma after removing prothrombin. Freund’s complete adjuvant is used in the first step of the immuni-zation procedure.
- 亚型
- IgG
- Top Product
- Discover our top product Fibrinogen Primary Antibody
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anti-Fibrinogen antibody
适用: 人, 大鼠 ELISA, IHC (p), IF (p), IHC (fro), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Fibrinogen antibody (Biotin)适用: 人 ELISA, WB, IHC 宿主: 山羊 Polyclonal Biotin
anti-Fibrinogen antibody适用: 人 IHC (p), IF (p) 宿主: 小鼠 Monoclonal 4F7 unconjugated
anti-Fibrinogen antibody适用: 人 ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Fibrinogen antibody适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C2 unconjugated
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- 应用备注
- In precipitating techniques as immunoelectrophoresis and single or double radial immunodiffusion (Mancini, Ouchterlony) to identify the presence of fibrinogen in mouse plasma or other body fluids or to determine its concentration.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 浓度
- Total protein and IgG concentrations in the antiserum are comparable to those of pooled normal goat serum. No foreign proteins added. Antibody titre: Precipitin titre 1:32 when tested against pooled normal mouse plasma in agar-block immunodiffusion titrat
- 缓冲液
- Delipidated, heat inactivated, lyophilized, stable whole antiserum
- 储存液
- Without preservative
- 储存条件
- 4 °C
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: "Deficiency of plasminogen receptor, Plg-RKT , causes defects in plasminogen binding and inflammatory macrophage recruitment in vivo." in: Journal of thrombosis and haemostasis : JTH, Vol. 15, Issue 1, pp. 155-162, (2018) (PubMed).
: "Vascular dysfunction and increased metastasis of B16F10 melanomas in Shb deficient mice as compared with their wild type counterparts." in: BMC cancer, Vol. 15, pp. 234, (2016) (PubMed).
: "Notch-independent RBPJ controls angiogenesis in the adult heart." in: Nature communications, Vol. 7, pp. 12088, (2016) (PubMed).
: "Histidine-rich glycoprotein uptake and turnover is mediated by mononuclear phagocytes." in: PLoS ONE, Vol. 9, Issue 9, pp. e107483, (2014) (PubMed).
: "Nanoparticles that sense thrombin activity as synthetic urinary biomarkers of thrombosis." in: ACS nano, Vol. 7, Issue 10, pp. 9001-9, (2014) (PubMed).
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: "Deficiency of plasminogen receptor, Plg-RKT , causes defects in plasminogen binding and inflammatory macrophage recruitment in vivo." in: Journal of thrombosis and haemostasis : JTH, Vol. 15, Issue 1, pp. 155-162, (2018) (PubMed).
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- 抗原
- Fibrinogen
- Abstract
- Fibrinogen 产品
- 别名
- fib2 antibody, MGC53620 antibody, fibrinogen antibody, sb:cb892 antibody, wu:fa55c12 antibody, wu:fb20e08 antibody, wu:fb59b03 antibody, wu:fi39d04 antibody, zgc:92117 antibody, fibrinogen alpha chain antibody, fibrinogen gamma chain antibody, fga antibody, FGA antibody, LOC698244 antibody, CpipJ_CPIJ010090 antibody, FGG antibody
- 背景
- The reactivity of the antiserum is restricted to mouse fibrinogen molecule. In immuno-electrophoresis and radial immunodiffusion, using various antiserum concentrations against normal mouse plasma a single precipitin line is obtained which shows a reaction of identity with the precipitin line obtained with purified fibrinogen. No reaction is obtained with any other plasma protein components or serum. However, the antiserum may also react with fibrin monomers, circulating fibrinopeptides and fibrin degradation products
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