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CDK2 抗体

This anti-CDK2 antibody is a 小鼠 单克隆 antibody detecting CDK2 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1106646
发货至: 中国

Quick Overview for CDK2 抗体 (ABIN1106646)

抗原

See all CDK2 抗体
CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

适用

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人, 小鼠, 大鼠

宿主

  • 212
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小鼠

克隆类型

  • 191
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单克隆

标记

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This CDK2 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

8A12
  • 特异性

    This antibody recognizes human Cdk2 and human Cdk5 and does not recognize human Cdc2 (Cdk1) on Western blot.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Protein A agarose

    免疫原

    Recombinant human Cdk2

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 溶解方式

    Prepare a stock solution by dissolving the lyophilized antibody 100 μL of distilled water. After reconstitution, the IgG concentration should be 1 mg/mL.

    缓冲液

    PBS ( pH 7.2) containing 1 % sucrose, 0.09 % NaN3

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Prior to reconstitution store at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.
  • 抗原

    CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

    别名

    CDK2

    背景

    Cellular proliferation is controlled by a family of protein kinases in which the catalytic subunits are members of the cyclin-dependent kinase (cdk) family and the regulatory subunits are cyclins. To date, nine distinct Cdks in addition to eight different cyclins have been identified, in which different CDK/cyclin combinations serve to regulate distinct points in the mammalian cell division cycle. Although Cdc2Hs (Cdk1)/cyclin B controls the transition of cells from the G2 to M-phase, the activities of Cdk2/cyclin E and Cdk2/cyclin A are critical for G1/S-phase transition and progression through S-phase.Synonyms: Cell division protein kinase 2, Cyclin dependent kinase 2, p33 protein kinase

    基因ID

    1017

    NCBI登录号

    NP_001789

    UniProt

    P24941

    途径

    PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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