CDK2 抗体
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北京 101111
Quick Overview for CDK2 抗体 (ABIN1106646)
抗原
See all CDK2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognizes human Cdk2 and human Cdk5 and does not recognize human Cdc2 (Cdk1) on Western blot.
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交叉反应 (详细)
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Protein A agarose
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免疫原
- Recombinant human Cdk2
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- Prepare a stock solution by dissolving the lyophilized antibody 100 μL of distilled water. After reconstitution, the IgG concentration should be 1 mg/mL.
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缓冲液
- PBS ( pH 7.2) containing 1 % sucrose, 0.09 % NaN3
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Prior to reconstitution store at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.
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- CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
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别名
- CDK2
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背景
- Cellular proliferation is controlled by a family of protein kinases in which the catalytic subunits are members of the cyclin-dependent kinase (cdk) family and the regulatory subunits are cyclins. To date, nine distinct Cdks in addition to eight different cyclins have been identified, in which different CDK/cyclin combinations serve to regulate distinct points in the mammalian cell division cycle. Although Cdc2Hs (Cdk1)/cyclin B controls the transition of cells from the G2 to M-phase, the activities of Cdk2/cyclin E and Cdk2/cyclin A are critical for G1/S-phase transition and progression through S-phase.Synonyms: Cell division protein kinase 2, Cyclin dependent kinase 2, p33 protein kinase
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基因ID
- 1017
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NCBI登录号
- NP_001789
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UniProt
- P24941
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途径
- PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
抗原
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