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MUC1 抗体

This 小鼠 单克隆 antibody specifically detects MUC1 in WB, FACS, IF, IHC (p), IP, IHC (fro), EIA 和 IEM. It exhibits reactivity toward 人.
产品编号 ABIN1106104
发货至: 中国
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北京 101111
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Quick Overview for MUC1 抗体 (ABIN1106104)

抗原

See all MUC1 抗体
MUC1 (Mucin 1 (MUC1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This MUC1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Immunoelectron Microscopy (IEM)

克隆位点

139H2
  • 特异性

    This Mouse monoclonal antibody has been raised against Human milk-fat globule membranes (HMFGM) to obtain reagents for mammary tumor diagnosis. This monoclonal reacts towards an peptide epitope in the repeat region of MUC-1.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Purified

    免疫原

    Deglycosylated purified MUC1 glycoprotein.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    MUC1 (Mucin 1 (MUC1))

    别名

    CD227 / Mucin-1 / MUC1

    背景

    Mucin 1, cell surface associated (MUC-1) or polymorphic epithelial mucin (PEM) is a mucin encoded by the MUC1 gene in humans. MUC-1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and several other organs. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with colon, breast, ovarian, lung and pancreatic cancers.Synonyms: Breast carcinoma-associated antigen DF3, CA 15-3, Carcinoma-associated mucin, DF3, EMA, Episialin, H23AG, MUC-1, PEMT, PUM, Peanut-reactive urinary mucin, Polymorphic epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin

    基因ID

    4582

    NCBI登录号

    NP_001018016

    UniProt

    P15941

    途径

    Negative Regulation of intrinsic apoptotic Signaling
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