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CCR5 抗体 (N-Term)

This anti-CCR5 antibody is a 兔 多克隆 antibody detecting CCR5 in WB 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1105992
发货至: 中国

Quick Overview for CCR5 抗体 (N-Term) (ABIN1105992)

抗原

See all CCR5 抗体
CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

适用

  • 150
  • 46
  • 40
  • 9
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 108
  • 37
  • 13
  • 3
  • 1
  • 1

克隆类型

  • 106
  • 50
  • 4
多克隆

标记

  • 91
  • 13
  • 9
  • 8
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This CCR5 antibody is un-conjugated

应用范围

  • 91
  • 68
  • 67
  • 26
  • 24
  • 21
  • 13
  • 13
  • 13
  • 11
  • 10
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 16
    • 13
    • 9
    • 9
    • 8
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    特异性

    This antibody detects CD195 / CCR5 (N-term).

    交叉反应 (详细)

    Species reactivity (tested):Human, Mouse, Rat.

    纯化方法

    Immunoaffinity Chromatography

    免疫原

    Synthetic peptide corresponding to a sequence at the N-terminal of Human CCR5 .Remarks: Sequence is different from the related rat sequence by two amino acids.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 溶解方式

    Restore with 0.2 mL of distilled water to a concentration of 500 μg/mL.

    缓冲液

    0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium Azide, 5 mg BSA

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

    别名

    CD195 / CCR5

    背景

    Human CC chemokine receptor 5 (CCR5), which is 17.5 kb from the CMKBR2 gene, encodes a 352-amino acid protein with a calculated molecular mass of 40,600 Da. It is organized into four exons and two introns. Human CCR5 is a co-receptor for macrophage-tropic strains of human immunodeficiency virus (HIV)-1 and is expressed by bone-marrow-derived cells. CCR5 is expressed on neurons, astrocytes, and microglia in the central nervous system, and on epithelium, endothelium, vascular smooth muscle and fibroblasts in other tissues. Functionally, CCR5 mediates the activation of cells by the chemokines macrophage inflammatory protein-1alpha, macrophage inflammatory protein-1beta, and RANTES, and serves as a fusion cofactor for macrophage-tropic strains of human immunodeficiency virus type 1.Synonyms: C-C CKR-5, C-C chemokine receptor type 5, CC-CKR-5, CCR-5, CHEMR13, CMKBR5, HIV-1 fusion coreceptor

    基因ID

    1234

    NCBI登录号

    NP_000570

    UniProt

    P51681

    途径

    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size
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