CCR3 抗体
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北京 101111
Quick Overview for CCR3 抗体 (ABIN1105989)
抗原
See all CCR3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts with CD193. The antibody has also been reported to inhibit chemotactic migration of monocyte-derived DCs to RANTES (Ref.4). It suppresses the capacity of monocyte-derived DCs to stimulate allogenetic TCs proliferation and TCs derived IFN-γ secretion (Ref.4).
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交叉反应 (详细)
- Species reactivity (tested):Human
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纯化方法
- Protein A agarose
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免疫原
- Human CCR3 expressing transfectant (mouse pre-B cell lymphoma B300-19)
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store (in aliquots) at -20 °C.
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- CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
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别名
- CD193 / CCR3
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背景
- Dendritic cells (DCs) are major antigen presenting cells (APCs) capable of stimulation resting T cells (TCs) in the primary immune response and are more potent APCs than peripheral blood monocytes or B cells. Several CC and CXC chemokines receptors were found to be expressed on some DCs and these molecules have been implicated to mediate in part the trafficking of DCs from blood to tissues and then to lymph nodes, where they form a close association with TCs in the process of antigen presentation. Recent studies have shown that CD191/CCR1 and CD193/CCR3 are potentially involved in antigen-presenting cell function of human DCs.Synonyms: C-C CKR-3, C-C chemokine receptor type 3, CC-CKR-3, CCR-3, CKR3, CMKBR3, Eosinophil eotaxin receptor
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基因ID
- 1232
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NCBI登录号
- NP_001828
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UniProt
- P51677
抗原
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