AKT1 抗体
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北京 101111
Quick Overview for AKT1 抗体 (ABIN110586)
抗原
See all AKT1 抗体适用
宿主
克隆类型
标记
应用范围
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限制
- 仅限研究用
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状态
- Lyophilized
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储存条件
- 4 °C
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- AKT1 (V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1))
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别名
- Akt/PKB
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背景
- Akt (also termed PKB, or RAC (Related to PKA and PKC), is the cellular homologue of the viral oncoprotein v-Akt. Akt is a serine / threonine kinases that consist of an N-terminal PH domain, a kinase domain and a C-termial domian similar to that of the PKC family. Akta contains 480 amino acids, and can be activated by receptor tyrosine kinases through the PI 3-kinase pathway. Akt has been shown to suppress apoptosis. Recent study suggests that Akt may also be part of the NF-.B activation pathway.
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途径
- PI3K-Akt Signaling, RTK signaling, TCR Signaling, AMPK Signaling, Interferon-gamma Pathway, TLR signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Water Deprivation, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Regulation of Cell Size, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, Positive Regulation of fat Cell Differentiation, VEGFR1 Specific Signals, VEGF Signaling, Warburg Effect
抗原
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