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Caspase 2 抗体 (C-Term)

This anti-Caspase 2 antibody is a 兔 多克隆 antibody detecting Caspase 2 in WB 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1105674
发货至: 中国

Quick Overview for Caspase 2 抗体 (C-Term) (ABIN1105674)

抗原

See all Caspase 2 (CASP2) 抗体
Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))

适用

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人, 小鼠, 大鼠

宿主

  • 112
  • 5
  • 3

克隆类型

  • 96
  • 24
多克隆

标记

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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This Caspase 2 antibody is un-conjugated

应用范围

  • 85
  • 37
  • 37
  • 20
  • 15
  • 14
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  • 10
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  • 2
  • 1
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 7
    • 6
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    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    This antibody detects Caspase-2 (C-term). No cross reactivity with other proteins.

    交叉反应 (详细)

    Species reactivity (expected):Mouse.
    Species reactivity (tested):Human, Rat.

    纯化方法

    Immunoaffinity Chromatography

    免疫原

    Synthetic peptide mapping at the C-terminal of Human Caspase 2 .Remarks: Sequence is identical to the related Rat and Mouse sequence.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 溶解方式

    0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    缓冲液

    0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium Azide, 5 mg BSA

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))

    别名

    Caspase-2

    背景

    Caspase-2, which is involved in stress-induced apoptosis, is recruited into a large protein complex, the molecular composition of which remains elusive. activation of caspase-2 occurs in a complex that contains the death domain-containing protein PIDD, whose expression is induced by p53, and the adaptor protein RAIDD. Increased PIDD expression resulted in spontaneous activation of caspase-2 and sensitization to apoptosis by genotoxic stimuli. Caspase-2 acts both as a positive and negative cell death effector, depending upon cell lineage and stage of development.Synonyms: CASP-2, CASP2, ICH-1 protease, ICH1, NEDD2, Neural precursor cell expressed developmentally down-regulated protein 2

    基因ID

    835

    NCBI登录号

    NP_116764

    UniProt

    P42575

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Neurotrophin Signaling Pathway
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