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- 抗原 See all PYCARD 抗体
- PYCARD (PYD and CARD Domain Containing (PYCARD))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PYCARD antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 特异性
- This antibody reacts with human ASC of U937, and HL-60, but not with Jurkat, HeLa, NB4, or HPB-ALL. It does not react with mouse NIH/3T3, L5178Y, or WR19L. It does not react with rat PC12.
- 纯化方法
- Protein A agarose
- 免疫原
- Triton X-100 insoluble fraction of retinoic acid-treated HL-60 cells
- 克隆位点
- 23-04-14
- 亚型
- IgG1
- Top Product
- Discover our top product PYCARD Primary Antibody
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anti-PYD and CARD Domain Containing (PYCARD) (AA 50-195) antibody
PYCARD 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (AA 50-195) antibodyPYCARD 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (C-Term) antibodyVerified PYCARD 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) antibodyPYCARD 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (AA 1-120) antibodyPYCARD 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 1C3D3 unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (Internal Region) antibodyVerified PYCARD 适用: 人, 小鼠, 大鼠 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (AA 1-149) antibodyPYCARD 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (N-Term) antibodyPYCARD 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (AA 1-195) antibodyPYCARD 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) antibodyPYCARD 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
- 储存液
- Without preservative
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store (in aliquots) at -20 °C.
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- 抗原
- PYCARD (PYD and CARD Domain Containing (PYCARD))
- 别名
- CARD5 / PYCARD / ASC (PYCARD 产品)
- 别名
- ASC antibody, CARD5 antibody, TMS antibody, TMS-1 antibody, TMS1 antibody, 9130417A21Rik antibody, Asc antibody, TNS1 antibody, masc antibody, asc1 antibody, zAsc antibody, zgc:109874 antibody, PYD and CARD domain containing antibody, PYCARD antibody, Pycard antibody, pycard antibody
- 背景
- ASC (apoptosis-associated speck-like protein containing a CARD (caspase recruitment domain)) is a 22 kDa soluble protein, located in the cytosol of HL-60 cells. In apoptotic HL-60 cells, it is able to visualized as a speck, forming an insoluble aggregate. The C-terminal domain of this protein contains a CARD, suggesting that ASC may have proapoptotic activity in HL-60 cells. Recent data have indicated that ASC plays a role of adaptor protein linking various PAAD (Pyrin, AIM, ASC, and death domain-like) family proteins to pathways involved in NF-κB and procaspase-1 activation.Synonyms: Caspase recruitment domain-containing protein 5, PYD and CARD domain-containing protein, TMS1, Target of methylation-induced silencing 1, poptosis-associated speck-like protein containing a CARD
- 分子量
- 22 kDa
- 基因ID
- 29108
- NCBI登录号
- NP_037390
- UniProt
- Q9ULZ3
- 途径
- Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation, Inflammasome
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