PYCARD 抗体
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北京 101111
Quick Overview for PYCARD 抗体 (ABIN1105662)
抗原
See all PYCARD 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts with human ASC of U937, and HL-60, but not with Jurkat, HeLa, NB4, or HPB-ALL. It does not react with mouse NIH/3T3, L5178Y, or WR19L. It does not react with rat PC12.
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纯化方法
- Protein A agarose
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免疫原
- Triton X-100 insoluble fraction of retinoic acid-treated HL-60 cells
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亚型
- IgG1
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anti-PYD and CARD Domain Containing (PYCARD) (AA 50-195) antibody
PYCARD 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) antibodyPYCARD 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (C-Term) antibodyVerified PYCARD 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) antibodyPYCARD 适用: 人 WB, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 3E9 unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (AA 1-120) antibodyPYCARD 适用: 人 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 1C3D3 unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (Internal Region) antibodyVerified PYCARD 适用: 人, 小鼠, 大鼠 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (N-Term) antibodyPYCARD 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (AA 1-149) antibodyPYCARD 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (AA 1-195) antibodyPYCARD 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (AA 1-195) antibodyPYCARD 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store (in aliquots) at -20 °C.
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- PYCARD (PYD and CARD Domain Containing (PYCARD))
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别名
- CARD5 / PYCARD / ASC
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背景
- ASC (apoptosis-associated speck-like protein containing a CARD (caspase recruitment domain)) is a 22 kDa soluble protein, located in the cytosol of HL-60 cells. In apoptotic HL-60 cells, it is able to visualized as a speck, forming an insoluble aggregate. The C-terminal domain of this protein contains a CARD, suggesting that ASC may have proapoptotic activity in HL-60 cells. Recent data have indicated that ASC plays a role of adaptor protein linking various PAAD (Pyrin, AIM, ASC, and death domain-like) family proteins to pathways involved in NF-κB and procaspase-1 activation.Synonyms: Caspase recruitment domain-containing protein 5, PYD and CARD domain-containing protein, TMS1, Target of methylation-induced silencing 1, poptosis-associated speck-like protein containing a CARD
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分子量
- 22 kDa
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基因ID
- 29108
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NCBI登录号
- NP_037390
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UniProt
- Q9ULZ3
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途径
- Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation, Inflammasome
抗原
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