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CD59 抗体 (AA 31-111)

Name: CD59 抗体 (AA 31-111)
Brand: antibodies-online
SKU: ABIN1098134
Availability: OutOfStock

CD59 适用: 人 FACS, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 8D2B8 unconjugated

Western blot analysis using CD59 mAb against human CD59 recombinant protein. (CD59 抗体 (AA 31-111))

Immunofluorescence analysis of MCF-7 cells using CD59 mouse mAb (green). (CD59 抗体 (AA 31-111))

Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using CD59 mouse mAb with DAB staining. (CD59 抗体 (AA 31-111))

IHC

Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using CD59 mouse mAb with DAB staining. (CD59 抗体 (AA 31-111))

IHC

Black line: Control Antigen (100 ng), Purple line: Antigen(10 ng), Blue line: Antigen (50 ng), Red line: Antigen (100 ng), (CD59 抗体 (AA 31-111))

ELISA

Flow cytometric analysis of HeLa cells using CD59 mouse mAb (green) and negative control (red). (CD59 抗体 (AA 31-111))

FACS

Western blot analysis using CD59 mAb against HEK293 (1) and CD59 (AA: 31-111)-hIgGFc transfected HEK293 (2) cell lysate. (CD59 抗体 (AA 31-111))

Immunofluorescence analysis of Hela cells using CD59 mouse mAb (green). (CD59 抗体 (AA 31-111))

8 images

(2 references)

产品编号 ABIN1098134

发货至: 中国

Datasheet as PDF

抗原 See all CD59 抗体

CD59
抗原表位
15

10

7

6

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 31-111
适用
127

8

8

7

3

1

1
人
宿主
76

60

6

4
小鼠
Compatible Secondaries
克隆类型
84

59

1
单克隆
标记
71

11

11

11

4

4

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
This CD59 antibody is un-conjugated
应用范围
87

55

42

35

25

23

20

16

12

12

12

11

11

11

3

3

1

1

1

1
Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

原理

CD59 Antibody

纯化方法

Purified antibody

免疫原

Purified recombinant fragment of human CD59 (AA: 31-111) expressed in E. Coli.

克隆位点

8D2B8

亚型

IgG1
anti-CD59 (CD59) (AA 74-110) antibody
CD59 适用: 人 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal RB56691 unconjugated

anti-CD59 (CD59) (AA 31-111) antibody
CD59 适用: 人 WB, FACS, IHC, ELISA, IF/ICC 宿主: 小鼠 Monoclonal unconjugated

anti-CD59 (CD59) (AA 23-105) antibody
CD59 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-CD59 (CD59) (AA 1-128) antibody
CD59 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G6 unconjugated

anti-CD59 (CD59) (AA 52-100) antibody
CD59 适用: 人 FACS, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-CD59 (CD59) (AA 26-102) antibody
CD59 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-CD59 (CD59) antibody
CD59 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 2E11B6 unconjugated

anti-CD59 (CD59) antibody
CD59 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated

anti-CD59 (CD59) (AA 1-128) antibody
CD59 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-CD59 (CD59) antibody
GMP Grade CD59 适用: 人 FACS 宿主: 小鼠 Monoclonal BRA-10G unconjugated

应用备注

ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/50 - 1/200

限制

仅限研究用
状态

Liquid

缓冲液

Purified antibody in PBS with 0.05 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Alegretti, Mucenic, Merzoni, Faulhaber, Silla, Xavier: "Expression of CD55 and CD59 on peripheral blood cells from systemic lupus erythematosus (SLE) patients." in: Cellular immunology, Vol. 265, Issue 2, pp. 127-32, (2010) (PubMed).

Ma, Chang, Qin, Sun, Huang, He: "Decreased expression of complement regulatory proteins, CD55 and CD59, on peripheral blood leucocytes in patients with type 2 diabetes and macrovascular diseases." in: Chinese medical journal, Vol. 122, Issue 18, pp. 2123-8, (2009) (PubMed).
抗原

CD59

别名

CD59 (CD59 产品)

背景

This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

分子量

14.2 kDa

基因ID

966

UniProt

P13987

途径

Complement System