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CD31 抗体

This 小鼠 单克隆 antibody specifically detects CD31 in WB 和 IHC. It exhibits reactivity toward 人.
产品编号 ABIN108424
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD31 抗体 (ABIN108424)

抗原

See all CD31 (PECAM1) 抗体
CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD31 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

CE6
  • 特异性

    The antibody reacts with Mr 135 000 PECAM-1 polypeptide from leukocytes and endothelial cells. Detects all endothelial cells in breast. Shows erythroid differentiation in human leukemic cells.

    免疫原

    Monoclonal antibody to PECAM-1 is derived from the hybridoma produced by fusion between myeloma cells and Balb/c spleen cells. Ulex Europaeus-agglutinin-I reactive glycoproteins from cultured human umbilical vein endothelial cells isolated by lecitin-affinity chromatography were used as immunogen

    亚型

    IgG1
  • 应用备注

    No reactivity with paraffin sections. Working dilution in western blotting is at least 1:1000

    限制

    仅限研究用
  • 储存条件

    4 °C
  • 抗原

    CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

    别名

    PECAM-1

    背景

    PECAM-1 (CE6) monoclonal antibody against PECAM-1 was produced to characterize human leukemic cells. PECAM-1 is typically an antigen that is shared by both endothelial and distinct hematopoietic cells. It is widely expressed among leukocytes and functions as cell adhesion molecule for these cells. PECAM-1 reactivity can be interpreted as a further evidence for megakaryocytic nature of distinct cell lines has been shown. However, a new useful application for this monoclonal antibody appears to be its very high reactivity against human endothelial cells. A recent review article states that in contrast to other applied endothelial markers, for instance PAL-E monoclonal antibody to endothelial cells and antibodies to factor VIII-related antigen, CE6 monoclonal antibody, reacts with all endothelial cells in human breast.

    途径

    Regulation of Actin Filament Polymerization
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