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CD59 抗体 (N-Term)

This anti-CD59 antibody is a 兔 单克隆 antibody detecting CD59 in WB 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN1077443
发货至: 中国

Quick Overview for CD59 抗体 (N-Term) (ABIN1077443)

抗原

See all CD59 抗体
CD59

适用

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人, 小鼠

宿主

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克隆类型

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  • 1
单克隆

标记

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This CD59 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    N-Term

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    Rabbit polyclonal CD59 antibody was raised against a 14 amino acid peptide near the amino terminus of human CD59.

    亚型

    IgG
  • 应用备注

    CD59 antibody can be used for detection of CD59 by Western blot at 1 - 2 μg/mL.

    说明

    (NT) CD59 molecule complement regulatory protein

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

    储存条件

    4 °C/-20 °C
  • 抗原

    CD59

    别名

    CD59

    背景

    The complement regulatory protein CD59 is a cell surface glycoprotein that regulates complement-mediated cell lysis and is involved in lymphocyte signal transduction. CD59 is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. CD59 also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and ultimately cerebral infarction.
    Synonyms: CD59 molecule complement regulatory protein, 1F5, EJ16, EJ30, EL32, G344, MIN1, MIN2, MIN3, MIRL, HRF20, MACIF, MEM43, MIC11, MSK21, 16.3A5, HRF-20, MAC-IP, p18-20

    分子量

    14 kDa

    基因ID

    966

    NCBI登录号

    NP_000602

    途径

    Complement System
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