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TGFB1 抗体

TGFB1 适用: 人, 小鼠, 大鼠, Cow, 绵羊, 兔, Mink WB, ELISA, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal TB21 unconjugated
产品编号 ABIN1042684
发货至: 中国
  • 抗原 See all TGFB1 抗体
    TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))
    适用
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    人, 小鼠, 大鼠, Cow, 绵羊, 兔, Mink
    宿主
    • 192
    • 41
    • 3
    • 1
    • 1
    小鼠
    克隆类型
    • 195
    • 42
    单克隆
    标记
    • 95
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    This TGFB1 antibody is un-conjugated
    应用范围
    • 180
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    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    Reacts with the dimeric (25 kDa) and monomeric (12.5 kDa) forms of TGF-beta under both non-reducing and reducing conditions respectively. This antibody recognizes both human platelet-derived and recombinant TGF-beta in ELISA
    纯化方法
    Protein G purified
    免疫原
    TGF-beta from human platelets
    克隆位点
    TB21
    亚型
    IgG1
    Top Product
    Discover our top product TGFB1 Primary Antibody
  • 应用备注
    Neutralizing: This antibody neutralizes TGF-beta activity in vitro, in an inhibition assay of CCL/64 cell growth and neutralizes the growth promoting action of TGF-beta in the NRK-49F colony forming assay. The effect of microinjection of this antibody into one blastomere of two cell stage Xenopus embryos indicated that it was able to neutralize effectively the bioactivity of TGF-beta in vivo. IHC: This antibody has been used to demonstrate TGF-beta in ovine ovarian tissue and human breast carcinoma at a dilution of 1:1000. As a consequence of the intense staining of the erythrocytes it is possible to locate a single cell within the ovarian stroma making it useful in locating very fine capillary networks within tissue. Western Blotting: This antibody when used at an antibody concentration of 5--20 ng/mL will allow visualization of 100 ng/lane of TGF-beta.
    说明

    Myeloma, fusion partners: Sp2/0 Ag.14

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Whole IgG in 0.01M PBS, pH 7.0
  • Crawford, Stellmach, Murphy-Ullrich, Ribeiro, Lawler, Hynes, Boivin, Bouck: "Thrombospondin-1 is a major activator of TGF-beta1 in vivo." in: Cell, Vol. 93, Issue 7, pp. 1159-70, (1998) (PubMed).

  • 抗原
    TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))
    别名
    TGF beta1  (TGFB1 产品)
    别名
    CED antibody, DPD1 antibody, LAP antibody, TGFB antibody, TGFbeta antibody, TGF-beta antibody, TGF-BETA-1 antibody, TGF-beta5 antibody, ced antibody, dpd1 antibody, lap antibody, tgf-beta antibody, tgfb antibody, tgfb5 antibody, tgfbeta antibody, TGF-beta1 antibody, TGFbeta1 antibody, Tgfb antibody, Tgfb-1 antibody, ai39657 antibody, tgfb1 antibody, wu:fb13a07 antibody, xx:ai39657 antibody, TGFB1 antibody, csd antibody, cdb1 antibody, cdg2 antibody, csd1 antibody, csd2 antibody, csd3 antibody, ebmd antibody, lcd1 antibody, bigh3 antibody, cdgg1 antibody, betaig-h3 antibody, TGFB4 antibody, transforming growth factor beta 1 antibody, transforming growth factor beta-1 antibody, transforming growth factor beta 1 L homeolog antibody, transforming growth factor, beta 1 antibody, transforming growth factor, beta 1a antibody, transforming growth factor beta induced L homeolog antibody, TGFB1 antibody, Tgfb1 antibody, tgfb1.L antibody, tgfb1a antibody, tgfbi.L antibody
    背景
    Synonyms:
    Camurati Engelmann disease antibody,CED antibody,Diaphyseal dysplasia 1 progressive antibody,DPD1antibody,LAP antibody,Latency-associated peptide antibody,TGF beta 1 antibody,TGF beta antibody,TGF-beta-1antibody,TGF-beta-5 antibody,TGF-beta1 antibody,TGFB 1 antibody,TGFB antibody,Tgfb-1 antibody,TGFB1antibody,TGFB1_HUMAN antibody,TGFbeta antibody,TGFbeta1 antibody,Transforming Growth Factor beta 1antibody,Transforming growth factor, beta 1a antibody
    UniProt
    P01137
    途径
    EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy, Cancer Immune Checkpoints
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