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HSP27 抗体

HSPB1 适用: 人 WB, IHC, ELISA, IP 宿主: 小鼠 Monoclonal G3-1 unconjugated
产品编号 ABIN100223
发货至: 中国
  • 抗原 See all HSP27 (HSPB1) 抗体
    HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This HSP27 antibody is un-conjugated
    应用范围
    • 253
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
    产品特性
    Concentration Definition: by UV absorbance at 280 nm
    过滤
    Sterile filtered
    免疫原
    This HSP27 monoclonal antibody was produced by repeated immunizations with a prokaryotic recombinant protein corresponding to the full length human hsp27 protein.
    Immunogentype:Recombinant
    克隆位点
    G3-1
    亚型
    IgG
    Top Product
    Discover our top product HSPB1 Primary Antibody
  • 应用备注
    This protein A purified monoclonal antibody against human Hsp27 has been tested for use in immunoblotting, immunoprecipitation, ELISA, immunohistochemistry and immunocytochemistry.  The antibody recognizes a 27 kDa band corresponding to hsp27 in cell lysates from breast carcinoma.    Both frozen sections and paraffin embedded material can be used for immunocytochemistry and immunohistochemistry.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液
    0.02 M Potassium Phosphate, 0.5 M Sodium Chloride, pH 7.2
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • McGuire, Fuqua, Naylor, Helin-Davis, McGuire: "Chromosomal assignments of human 27-kDa heat shock protein gene family." in: Somatic cell and molecular genetics, Vol. 15, Issue 2, pp. 167-71, (1989) (PubMed).

    Moretti-Rojas, Fuqua, Montgomery, McGuire: "A cDNA for the estradiol-regulated 24K protein: control of mRNA levels in MCF-7 cells." in: Breast cancer research and treatment, Vol. 11, Issue 2, pp. 155-63, (1988) (PubMed).

    Edwards, Adams, McGuire: "Estradiol stimulates synthesis of a major intracellular protein in a human breast cancer cell line (MCF-7)." in: Breast cancer research and treatment, Vol. 1, Issue 3, pp. 209-23, (1983) (PubMed).

  • 抗原
    HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))
    别名
    HSP27 (HSPB1 产品)
    背景
    Heat shock protein (HSP) 27 is one of the small HSPs that are constitutively expressed at different levels in different cell types and tissues (this protein has also been referred to as the Estrogen-Regulated 24 kDa protein, hsp25 and hsp28).   Like other small heat shock proteins, HSP27 is regulated at both the transcriptional and post-translational level.  In response to stress, the expression level of HSP27 increases several-fold to confer cellular resistance to the adverse environmental change.  Human HSP27 shares greater than 50% homology with the low molecular weight Drosophila HSP and mammalian crystalline lens protein.  Because of the estrogen responsive nature of HSP27, the protein has been extensively
    Synonyms: Heat shock protein beta-1 antibody, HspB1 antibody, Heat shock 27 kDa protein antibody, Stress-responsive protein 27 antibody, SRP27 antibody, Estrogen-regulated 24 kDa protein antibody, 28 kDa heat shock protein antibody
    基因ID
    39078, 17647521
    UniProt
    P04792
    途径
    MAPK Pathway, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, VEGF Signaling
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