ANAPC4 抗体
(Anaphase Promoting Complex Subunit 4 (ANAPC4))
A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The exact function of this gene product is not known. [provided by RefSeq, Jul 2008].
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Latest Publications for our ANAPC4 抗体
: "Hyperphosphorylation of CDH1 in Glioblastoma Cancer Stem Cells Attenuates APC/CCDH1 Activity and Pharmacologic Inhibition of APC/CCDH1/CDC20 Compromises Viability." in: Molecular cancer research : MCR, Vol. 17, Issue 7, pp. 1519-1530, (2019) (PubMed).: "Sphingosine kinase 1 is overexpressed and promotes proliferation in human thyroid cancer." in: Molecular endocrinology (Baltimore, Md.), Vol. 25, Issue 11, pp. 1858-66, (2011) (PubMed).
Aliases for ANAPC4 抗体
anaphase promoting complex subunit 4 (Anapc4) 抗体anaphase promoting complex subunit 4 L homeolog (anapc4.L) 抗体
anaphase promoting complex subunit 4 (ANAPC4) 抗体
anaphase promoting complex subunit 4 (anapc4) 抗体
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