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AKR1C1 抗体

(Dihydrodiol Dehydrogenase (DDH))
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008].

37 results :

KO Validated DDH 适用: 人 WB, IHC, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
Pubmed 3 references
产品编号 ABIN2856139
 
DDH 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
Pubmed 2 references
产品编号 ABIN560581
 
DDH 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN514922
 
DDH 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B3 unconjugated
产品编号 ABIN1327000
 
DDH 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
Pubmed 3 references
产品编号 ABIN514921
 
DDH 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal AT6D10 unconjugated
产品编号 ABIN962119
 
DDH 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7143686
 
DDH 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7256524
 
DDH 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6136721
 
DDH 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN926427
 
DDH 适用: 人, 大鼠, 小鼠, Cow, 犬, 马, 兔, 豚鼠, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2788359
 
DDH 适用: 人, 大鼠, Cow, 犬, 马, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2788358
 
DDH 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7188688
 
DDH 适用: 人 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7143689
 
DDH 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7143688
 
DDH 适用: 人 ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN7143687
 
DDH 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7113480
 
DDH 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1817251
 
DDH 适用: 人 WB, IHC (f) 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN7126291
 
DDH 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6755520
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • ELISA
    • Immunohistochemistry (IHC)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunofluorescence (IF)
    • Immunocytochemistry (ICC)
    • Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
    • Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    • Immunoprecipitation (IP)
    • Immunofluorescence (fixed cells) (IF/ICC)
  • 适用
    • Human
    • Rat
    • Mouse
    • Cow
    • Dog
    • Horse
    • Rabbit
    • Guinea Pig
    • Monkey
    • Pig
    • Sheep
  • 论文引用
  • 图像
  • Preservative free only
  • Carrier free only
  • 抗体来源
    • Rabbit
    • Mouse
  • 克隆形成能力
    • Polyclonal
    • Monoclonal
  • 克隆
    • AT6D10
    • 1B3
  • 抗原表位
    • AA 1-323
    • AA 219-323
    • N-Term
    • AA 1-110
    • AA 22-248
    • AA 2-218
    • AA 22-218
    • AA 50-99
    • AA 99-148
    • C-Term
  • 标记
    • 非结合性
    • Biotin
    • FITC
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
    • HRP
  • 抗体亚型
    • IgG
    • IgG1 kappa
    • IgG1
    • IgG2a
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • KO Validated
  • Supplier
    • antibodies-online
    • Signalway
    • Aviva Systems Biology
    • Abbexa
    • Covalab
    • RayBiotech

Latest Publications for our AKR1C1 抗体

Zhu, Hu, Zeng, Chang, Ge, Wang, Yan, Zhao, Cao, Ying, Gu, Zheng, He, Yang: "The SIRT2-mediated deacetylation of AKR1C1 is required for suppressing its pro-metastasis function in Non-Small Cell Lung Cancer." in: Theranostics, Vol. 10, Issue 5, pp. 2188-2200, (2020) (PubMed).

Zeng, Zhu, You, Dong, Yang, Zhu, He: "Liquiritin, as a Natural Inhibitor of AKR1C1, Could Interfere With the Progesterone Metabolism." in: Frontiers in physiology, Vol. 10, pp. 833, (2019) (PubMed).

Zhu, Chang, Yan, Hu, Zeng, Zhou, Yuan, Ying, Cao, He, Yang: "AKR1C1 Activates STAT3 to Promote the Metastasis of Non-Small Cell Lung Cancer." in: Theranostics, Vol. 8, Issue 3, pp. 676-692, (2018) (PubMed).

Chen, Solomides, Parekh, Simpkins, Simpkins: "Cisplatin resistance in human cervical, ovarian and lung cancer cells." in: Cancer chemotherapy and pharmacology, Vol. 75, Issue 6, pp. 1217-27, (2015) (PubMed).

Han, Bourboulia, Jensen-Taubman, Isaac, Wei, Stetler-Stevenson: "An endogenous inhibitor of angiogenesis inversely correlates with side population phenotype and function in human lung cancer cells." in: Oncogene, Vol. 33, Issue 9, pp. 1198-206, (2014) (PubMed).

Choi, Ryoo, Kang, Kwak: "The sensitivity of cancer cells to pheophorbide a-based photodynamic therapy is enhanced by Nrf2 silencing." in: PLoS ONE, Vol. 9, Issue 9, pp. e107158, (2014) (PubMed).

Ebert, Kisiela, Wsól, Maser: "Proteasome inhibitors MG-132 and bortezomib induce AKR1C1, AKR1C3, AKR1B1, and AKR1B10 in human colon cancer cell lines SW-480 and HT-29." in: Chemico-biological interactions, Vol. 191, Issue 1-3, pp. 239-49, (2011) (PubMed).

Buytaert, Matroule, Durinck, Close, Kocanova, Vandenheede, de Witte, Piette, Agostinis: "Molecular effectors and modulators of hypericin-mediated cell death in bladder cancer cells." in: Oncogene, Vol. 27, Issue 13, pp. 1916-29, (2008) (PubMed).

McLoughlin, Irving, Brownlees, Brion, Leroy, Miller: "Mint2/X11-like colocalizes with the Alzheimer's disease amyloid precursor protein and is associated with neuritic plaques in Alzheimer's disease." in: The European journal of neuroscience, Vol. 11, Issue 6, pp. 1988-94, (1999) (PubMed).

Borg, Straight, Kaech, de Taddéo-Borg, Kroon, Karnak, Turner, Kim, Margolis: "Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting." in: The Journal of biological chemistry, Vol. 273, Issue 48, pp. 31633-6, (1998) (PubMed).

Aliases for AKR1C1 抗体

aldo-keto reductase family 1 member C1 (AKR1C1) 抗体
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) (AKR1C1) 抗体
2-ALPHA-HSD 抗体
20-ALPHA-HSD 抗体
C9 抗体
DD1 抗体
DD1/DD2 抗体
DDH 抗体
DDH1 抗体
H-37 抗体
HAKRC 抗体
HBAB 抗体
MBAB 抗体
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