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AKR1C1 抗体

The 小鼠 单克隆 anti-AKR1C1 antibody (Clone CPTC-AKR1C1-2) (ABIN7126291) specifically detects AKR1C1 in WB 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7126291
发货至: 中国
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Quick Overview for AKR1C1 抗体 (ABIN7126291)

抗原

See all AKR1C1 (DDH) 抗体
AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This AKR1C1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

CPTC-AKR1C1-2
  • 原理

    Aldo-keto Reductase Family 1 Member C1 / DD1 Antibody

    特异性

    DDH / AKR1C1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone.

    交叉反应 (详细)

    Human.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant human full-length AKR1C1 protein

    亚型

    IgG1, kappa
  • 应用备注

    Known_Application: Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: HepG2 or A549 cells. Human liver or stomach tissue.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

    别名

    AKR1C1

    背景

    2-dihydrobenzene-1, 2-diol dehydrogenase, 20 alpha (3 alpha) hydroxysteroid dehydrogenase, 20ALPHAHSD, 2ALPHAHSD, AK1C1, C9, Chlordecone reductase homolog HAKRC, DD1/DD2, DDH1, Dihydrodiol dehydrogenase 1/2, H37, HBAB, Hepatic dihydrodiol dehydrogenase, High affinity hepatic bile acid-binding protein, Indanol dehydrogenase, MBAB, Trans-1,2 dihydrobenzene 1,2 diol dehydrogenase, Type II 3 alpha hydroxysteroid dehydrogenase

    HepG2 or A549 cells. Human liver or stomach tissue.

    分子量

    37kDa

    基因ID

    1645, 460260

    UniProt

    Q04828

    途径

    Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
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