This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
Blakey, Halapi, Bjornsdottir, Wheatley, Kristinsson, Upmanyu, Stefansson, Hakonarson, Hall: "Contribution of ADAM33 polymorphisms to the population risk of asthma." in: Thorax, Vol. 60, Issue 4, pp. 274-6, (2005) (PubMed).
Powell, Wicks, Holloway, Holgate, Davies: "The splicing and fate of ADAM33 transcripts in primary human airways fibroblasts." in: American journal of respiratory cell and molecular biology, Vol. 31, Issue 1, pp. 13-21, (2004) (PubMed).
Aliases for ADAM33 抗体
ADAM metallopeptidase domain 33 (ADAM33) 抗体 disintegrin and metalloproteinase domain-containing protein 19-like (LOC100230755) 抗体 a disintegrin and metallopeptidase domain 33 (Adam33) 抗体 ADAM metallopeptidase domain 33 L homeolog (adam33.L) 抗体 ADAM metallopeptidase domain 33 (Adam33) 抗体 ADAM13 抗体 adam13 抗体 ADAM33 抗体 Adaml 抗体 C20orf153 抗体 DJ964F7.1 抗体