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抗Human Angiotensin II Type 2 Receptor 抗体:
抗Mouse (Murine) Angiotensin II Type 2 Receptor 抗体:
抗Rat (Rattus) Angiotensin II Type 2 Receptor 抗体:
Human Polyclonal Angiotensin II Type 2 Receptor Primary Antibody for ELISA, ICC - ABIN4278731
Hafko, Villapol, Nostramo, Symes, Sabban, Inagami, Saavedra: Commercially available angiotensin II At₂ receptor antibodies are nonspecific. in PLoS ONE 2013
Show all 9 Pubmed References
angiotensin II type 2 receptor activation in inguinal adipocytes opposes norepinephrine-induced uncoupling protein-1 (UCP1 (显示 UCP1 抗体)) production and aspects of cellular respiration
loss of AT2 R is associated with podocyte loss/dysfunction and is mediated, at least in part, via augmented ectopic hedgehog interacting protein (显示 HHIP 抗体) expression in podocytes
In this genomewide association study, we found that variants at the EBF1 (显示 EBF1 抗体), EEFSEC (显示 EEFSEC 抗体), AGTR2, WNT4 (显示 WNT4 抗体), ADCY5 (显示 ADCY5 抗体), and RAP2C (显示 RAP2C 抗体) loci were associated with gestational duration and variants at the EBF1 (显示 EBF1 抗体), EEFSEC (显示 EEFSEC 抗体), and AGTR2 loci with preterm birth.
crystal structures of human AT2R bound to an AT2R-selective ligand and to an AT1R (显示 AGTR1 抗体)/AT2R dual ligand, capturing the receptor in an active-like conformation
Suggest a gender-specific association between the AT2R -1332 A/G polymorphism and the occurrence of carotid plaque and the history of cerebrovascular insult in advanced carotid atherosclerosis.
peripheral and central arterial pressures and pulse wave augmentation indexes (AIx(P), AIx(C1), AIx(C2)), pulse wave velocity (PWV), daily urinary sodium excretion were measured and did genetic studies of AGTR1 (显示 AGTR1 抗体) A1166C and AGTR2 G1675A polymorphisms.
Significant overrepresentation of AT2R-1332 AA genotype in female multiple sclerosis patients was found, compared to female controls.
These data suggest that AT2R inhibits ligand-induced AT1R signaling through the PKC-dependent pathway.
Ang II (显示 AGT 抗体)-induced upregulation of ATF3 (显示 ATF3 抗体) and SUMO1 (显示 SUMO1 抗体) in vitro and in vivo was blocked by Ang II (显示 AGT 抗体) type I receptor antagonist olmesartan. Moreover, Ang II (显示 AGT 抗体) induced ATF3 (显示 ATF3 抗体) SUMOylation at lysine 42, which is SUMO1 (显示 SUMO1 抗体) dependent
The A1166C polymorphism of AT1R (显示 AGTR1 抗体), A1675G and C3123A polymorphisms of AT2R were analyzed. The A1675G polymorphism of AT2R might be associated with preeclampsia
crosstalk between AT2 receptor stimulation and PPARgamma (显示 PPARG 抗体) activation could contribute to attenuation of vascular intimal proliferation
Deletion of AT2 receptor reduced SHP-1 activity and restored VEGF actions, leading to an increased blood flow reperfusion after ischemia in diabetes mellitus.
Our current results reinforce the notion that the AT2R has a physiological role in the conservation of insulin (显示 INS 抗体) action
Ultra-high doses did not influence the ACE2 (显示 ACE2 抗体)/AT2R/Mas (显示 MAS1 抗体) axis and promoted renal injury with increased renal ERK1/2 (显示 MAPK1/3 抗体) activation and exaggerated fibronectin (显示 FN1 抗体) expression in db/db (显示 LEPR 抗体) mice. Our study demonstrates dose-related effects of candesartan in diabetic nephropathy: intermediate-high dose candesartan is renoprotective, whereas ultra-high dose candesartan induces renal damage.
This study aimed to define whether sex chromosome complement (SCC (显示 CYP11A1 抗体)) may differentially modulate sex differences in relative gene expression of basal Agtr1a (显示 AGTR1 抗体), Agtr2, and Mas1 (显示 MAS1 抗体) receptors at fore/hindbrain nuclei and at medulla/cortical kidney.
AT2R-dependent interleukin-17 (显示 IL17A 抗体) production by T lymphocyte is necessary for collateral artery growth.
Altered expression of AT1 and AT2 receptors with aging may induce mitochondrial dysfunction, the main risk factor for neurodegeneration.
AT2R inhibits adipogenic differentiation in mesenchymal stem cells. Moreover, this inhibitory effect is associated with Wnt10b (显示 WNT10B 抗体)/beta-catenin (显示 CTNNB1 抗体) signaling.
These results suggest that nerve growth factor-mediated neurite outgrowth is suppressed by AT2 receptor signaling via the nitric oxide-cyclic GMP (显示 NT5C2 抗体)-PKG (显示 PRKG1 抗体) pathway.
Luminal ANG II is internalized as a complex with AT1R/AT2R heterodimers to target endoplasmic reticulum in LLC-PK1 cells, where it might trigger intracellular calcium responses.
AT1 (显示 AGTR1 抗体) and AT2 receptors heterodimerize and are involved in the angiotensin II effect on SERCA (显示 ATP2A3 抗体) in proximal kidney tubules.
AT2 receptors are positively coupled to the proliferative response of vascular smooth muscle cells to angiotensin II.
Glomerular eNOS (显示 NOS3 抗体) gene expression was studied during postnatal maturation and AT1 receptor (显示 AGTRAP 抗体) inhibition.
Data suggest that AGTR2 (and angiotensin-converting enzyme (显示 ACE 抗体)) mRNA levels are transiently up-regulated in ovarian theca cells during preovulatory period.
data suggest that G alpha(i3), Shc (显示 SHC1 抗体), Grb2 (显示 GRB2 抗体), Ras, and Raf-1 (显示 RAF1 抗体) link Src (显示 SRC 抗体) to activation of MAPK (显示 MAPK1 抗体) and to the AT(2)-dependent increase in eNOS (显示 NOS3 抗体) expression in PAECs
Abundance of AGTR2 mRNA in granulosa cells was higher in healthy compared with atretic follicles, whereas in theca cells, it did not change
The protein encoded by this gene belongs to the G-protein coupled receptor 1 family, and functions as a receptor for angiotensin II. It is an intergral membrane protein that is highly expressed in fetus, but scantily in adult tissues, except brain, adrenal medulla, and atretic ovary. This receptor has been shown to mediate programmed cell death and this apoptotic function may play an important role in developmental biology and pathophysiology. Mutations in this gene are been associated with X-linked mental retardation.
angiotensin II type-2 receptor
, type-2 angiotensin II receptor
, AT2 receptor
, angiotensin II type 2 receptor
, angiotensin receptor 2
, angiotensin II receptor type 2
, angiotensin type II receptor
, Type-2 angiotensin II receptor
, angiotensin II subtype 2 receptor, AT2