anti-serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9) 抗体

SERPINB9 encodes a member of the serine protease inhibitor family which are also known as serpins. 再加上,我们可以发SERPINB9 试剂盒 (8)SERPINB9 蛋白 (8)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
SERPINB9 361241  
SERPINB9 20723  
SERPINB9 5272 P50453
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antibodies-online.cn销售最多的anti-SERPINB9 抗体

Showing 10 out of 112 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
山羊 非结合性 ELISA, WB ABIN190825 (0.5µg/ml) staining of Human Placenta lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg 6至7个工作日
小鼠 非结合性 WB 100 μg 2至3个工作日
非结合性 IP, IHC, WB Immunohistochemical analysis of Serpin B9 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of Serpin B9 expression in Ramos (A), HuvEc (B) whole cell lysates. 200 μL 13至14个工作日
非结合性 IHC, ELISA, WB Western blot analysis of extracts from COLO/HuvEc/Jurkat cells, using SERPINB9 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using SERPINB9 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2至3个工作日
非结合性 WB   100 μg 2至3个工作日
非结合性 ICC, IHC, WB Figure. Western Blot; Sample: Lane1: Human Serum; Lane2: Mouse Placenta Tissue. Figure. Western Blot; Sample: Recombinant CAP3, Human. 100 μg 13至16个工作日
非结合性 ELISA, IHC, WB 100 μL Available
Hamster 山羊 非结合性 ELISA, WB 100 μg 11至14个工作日
非结合性 WB SERPINB9 Antibody (Center) (ABIN1881792) western blot analysis in NCI-H292 cell line lysates (35 µg/lane). This demonstrates the SERPINB9 antibody detected the SERPINB9 protein (arrow). 400 μL 10至11个工作日
非结合性 ELISA, ICC, IF, IHC, WB ABIN6275557 staining  COLO205 cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibod ABIN6275557 at 1/100 staining Mouse liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL 11至12个工作日

引用最多的anti-SERPINB9 抗体

  1. Human Monoclonal SERPINB9 Primary Antibody for FACS - ABIN2476137 : Hall, Keane: Proceedings: Dopaminergic and cholinergic interactions in the caudate nucleus in relation to the induction of sleep in the cat. in British journal of pharmacology 1975 (PubMed)
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  2. Human Monoclonal SERPINB9 Primary Antibody for IHC (fro), FACS - ABIN2476136 : Hirst, Buzza, Sutton, Trapani, Loveland, Bird: Perforin-independent expression of granzyme B and proteinase inhibitor 9 in human testis and placenta suggests a role for granzyme B-mediated proteolysis in reproduction. in Molecular human reproduction 2001 (PubMed)
    Show all 4 Pubmed References

  3. Mouse (Murine) Polyclonal SERPINB9 Primary Antibody for FACS, WB - ABIN2192172 : Zhang, Byrne, Liu, Wang, Oxenius, Ashton-Rickardt: Differential survival of cytotoxic T cells and memory cell precursors. in Journal of immunology (Baltimore, Md. : 1950) 2007 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal SERPINB9 Primary Antibody for IF, WB - ABIN6147596 : Deng, Zou, Xiong, Wang, Engelhardt, Ye, Yan, Qiu: Human Parvovirus Infection of Human Airway Epithelia Induces Pyroptotic Cell Death by Inhibiting Apoptosis. in Journal of virology 2017 (PubMed)

  5. Human Polyclonal SERPINB9 Primary Antibody for ELISA, WB - ABIN188847 : Jiang, Ellison, Alarid, Shapiro: Interplay between the levels of estrogen and estrogen receptor controls the level of the granzyme inhibitor, proteinase inhibitor 9 and susceptibility to immune surveillance by natural killer cells. in Oncogene 2007 (PubMed)


Pig (Porcine) serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9) interaction partners

  1. Cloning of pig serine proteinase inhibitor 9.

Mouse (Murine) serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9) interaction partners

  1. These findings add support for role for Sb9 cross-presentation, and indicate that high Sb9 expression is a novel marker of cross-presentation capable dendritic cells

  2. Data suggest that reactive oxygen species (ROS) generated within cytotoxic lymphocytes by receptor stimulation are required for lysosomal permeabilization and release of GzmB (granzyme B) into the cytosol and for inactivation of serpin B9.

  3. our data demonstrate, for the first time, a novel role for Spi6 in Regulatory T cell homeostasis

  4. Data indicate that Serpinb9 (Spi6)-deficient dendritic cells appear to process antigen faster.

  5. the negative regulation of DC priming of CD8 T lymphocyte immunity by CTL killing is mitigated by the physiological inhibition of GrB by Spi6.

  6. SPI6 protects mesenchymal stem cells from GrB-mediated killing and plays a pivotal role in their survival in vivo.

  7. Data show that increased activation-induced apoptosis resulted in impaired survival and a decreased clonal burst size of Spi6 KO iNKT cells, which could be corrected by GrB deficiency.

  8. SPI-CI is a novel immune escape molecule that acts in concert with SPI-6 to prevent cytotoxic lymphocyte-mediated killing of tumor cells.

  9. Estrogen induction of PI-9 may reduce the ability of cytolytic lymphocytes-mediated immune surveillance to destroy newly transformed cells

  10. In mCAP3, an intact catalytic triad was necessary for activation of ENaC but not for intramolecular cleavage of the protease.

  11. protects hepatocytes against excessively vigorous granzyme B-dependent killing but may also delay immune clearance of virally infected hepatocytes

  12. deficiency in a weak intracellular inhibitor of neutrophil elastase results in an acute inflammatory response that protects from P. aeruginosa but does not cause lung disease

  13. SPI-6 is selectively up-regulated in hepatocytes in response to infiltration of the liver by NK cells that express perforin and enzymatically active granzyme B.

  14. Increased SPI-6 expression is not sufficient to confer lipopolysaccharide-treated dendritic cells with resistance to direct killing in vivo.

Human serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9) interaction partners

  1. Data show that the serine protease inhibitor B9 (serpinB9) mediated caspase-1 inhibition regulates IL-1beta release in monocytes.

  2. Treatment with estrogens further increased PI-9 level while decreased that of ERalpha66 isoform thus excluding the involvement of this receptor isoform in the event. Moreover, our studies also provided evidence that tertiary tumorspheres express elevated levels of CXCR4 and phospho-p38, suggesting that the high PI-9 content might be ascribed to the activation of the proliferative CXCR4/phospho-p38 axis.

  3. We filtered four OSCC genes including SERPINB9, SERPINE2, GAK, and HSP90B1 through the gene global prioritization score (P < 0.005).

  4. Data show that oropharyngeal squamous cell carcinomas (OPSCCs) express granzyme inhibitors SERPINB1, SERPINB4 and SERPINB9 for cytotoxicity and the expression was not different between human papillomavirus (HPV)-positive and HPV-negative tumors.

  5. Pediatric CNS-PNETs evade immune recognition by downregulating cell surface MHC-I and CD1d expression. Intriguingly, expression of SERPINB9, SERPINB1, and SERPINB4 is acquired during tumorigenesis in 29%, 29%, and 57% of the tumors

  6. Data suggest that reactive oxygen species (ROS) generated within cytotoxic lymphocytes by receptor stimulation are required for lysosomal permeabilization and release of GzmB (granzyme B) into the cytosol and for inactivation of serpin B9.

  7. Increased intracellular PI-9 activity in mononuclear phagocytes from HIV-infected patients contributes to successful intracellular infection by virulent Mycobacterium tuberculosis.

  8. The GrB-Sb9 nexus may therefore represent an additional mechanism of limiting lymphocyte lifespan and populations.

  9. Suppression of granzyme B initiated apoptosis in protease inhibitor-9-expressing leukemia cells.

  10. SerpinB9 expression in human renal tubular epithelial cells is induced by triggering of the viral dsRNA sensors TLR3, MDA5 and RIG-I during subclinical rejection.

  11. lung cancer cells utilise their increased PI-9 expression to protect from granzyme B-mediated cytotoxicity as an immune evasion mechanism

  12. Inhibition of Granzyme B by PI-9 protects prostate cancer cells from apoptosis.

  13. Reduced proteinase inhibitor 9 expression in human vascular smooth muscle cells is associated with atherosclerotic disease progression.

  14. PI-9 induction within human mononuclear phagocytes by virulent Mycobacterium tuberculosis serves to protect these primary targets of infection from elimination by apoptosis and thereby promotes intracellular survival of the organism.

  15. constitutive expression of serine protease inhibitor 9 (PI-9) on human peripheral blood-and bone marrow-derived mesenchymal stem cells is a major defense mechanism against granzyme B-mediated destruction by NK cells

  16. upregulated expression of PI-9 in NSCLC cells may serve to protect them from apoptosis induced by GrB

  17. Expression levels of apoptosis-related proteins caspase 3, Bcl-2, and PI9 predict clinical outcome in anaplastic large cell lymphoma.

  18. The presence and subcellular localization of proteinase inhibitor 9 in leukocytes and dendritic cells are consistent with a protective role against ectopic or misdirected granzyme B during an immune response.

  19. a high expression of PI-9 by tubular epithelial cells can serve as one of the factors protecting renal allografts from rejection in spite of the presence of inflammatory cell infiltrates.

  20. proteinase inhibitor 9 was effectively hydrolyzed and inactivated by human granzyme M, raising the possibility that this orphan granzyme bypasses proteinase inhibitor 9 inhibition of granzyme B



This gene encodes a member of the serine protease inhibitor family which are also known as serpins. The encoded protein belongs to a subfamily of intracellular serpins. This protein inhibits the activity of the effector molecule granzyme B. Overexpression of this protein may prevent cytotoxic T-lymphocytes from eliminating certain tumor cells. A pseudogene of this gene is found on chromosome 6.

Gene names and symbols associated with SERPINB9

  • serpin family B member 9 (Serpinb9) 抗体
  • serpin family B member 9 (SERPINB9) 抗体
  • serpin peptidase inhibitor, clade B (ovalbumin), member 9 (SERPINB9) 抗体
  • serine (or cysteine) peptidase inhibitor, clade B, member 9 (Serpinb9) 抗体
  • BB283241 抗体
  • CAP-3 抗体
  • CAP3 抗体
  • ovalbumin 抗体
  • PI-9 抗体
  • PI9 抗体
  • SERPINB9 抗体
  • Spi6 抗体

Protein level used designations for SERPINB9

serine (or cysteine) peptidase inhibitor, clade B, member 9 , serpin B9 , serpin peptidase inhibitor, clade B (ovalbumin), member 9 , serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9 , Cytoplasmic antiproteinase 3 , serpin B9-like , serine (or cysteine) proteinase inhibitor, clade B, member 9 , serine protease inhibitor 6 , cytoplasmic antiproteinase 3 , peptidase inhibitor 9 , protease inhibitor 9 (ovalbumin type) , serpin peptidase inhibitor, clade B, member 9

361241 Rattus norvegicus
488192 Canis lupus familiaris
524513 Bos taurus
707580 Macaca mulatta
744242 Pan troglodytes
100126851 Sus scrofa
100388662 Callithrix jacchus
100445070 Pongo abelii
100596895 Nomascus leucogenys
20723 Mus musculus
5272 Homo sapiens
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