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SERPINB9 抗体

SERPINB9 适用: 小鼠 WB, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2192172
发货至: 中国
  • 抗原 See all SERPINB9 抗体
    SERPINB9 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9))
    适用
    • 37
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    小鼠
    宿主
    • 31
    • 7
    • 1
    克隆类型
    • 33
    • 6
    多克隆
    标记
    • 27
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    • 1
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    • 1
    • 1
    • 1
    • 1
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    This SERPINB9 antibody is un-conjugated
    应用范围
    • 29
    • 16
    • 11
    • 5
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    Western Blotting (WB), Flow Cytometry (FACS)
    过滤
    0.2 μm filtered
    Top Product
    Discover our top product SERPINB9 Primary Antibody
  • 应用备注
    For flow cytometry and Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.
    限制
    仅限研究用
  • 缓冲液
    PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
    有效期
    12 months
  • Zhang, Byrne, Liu, Wang, Oxenius, Ashton-Rickardt: "Differential survival of cytotoxic T cells and memory cell precursors." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 6, pp. 3483-91, (2007) (PubMed).

    Zhang, Liu, Park, Wang, Byrne, Murmann, Bahr, Peter, Olson, Belaaouaj, Ashton-Rickardt: "Serine protease inhibitor 6-deficient mice have increased neutrophil immunity to Pseudomonas aeruginosa." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 7, pp. 4390-6, (2007) (PubMed).

  • 抗原
    SERPINB9 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9))
    别名
    Spi-6 (SERPINB9 产品)
    别名
    SERPINB9 antibody, BB283241 antibody, CAP-3 antibody, CAP3 antibody, PI-9 antibody, PI9 antibody, Spi6 antibody, ovalbumin antibody, serpin family B member 9 antibody, serpin peptidase inhibitor, clade B (ovalbumin), member 9 antibody, serine (or cysteine) peptidase inhibitor, clade B, member 9 antibody, Serpinb9 antibody, SERPINB9 antibody
    背景
    The polyclonal antibody recognizes mouse Spi-6, also known as serpin B9, a cytoplasmic serine protease inhibitor of ~42 kD. Spi-6 is expressed in dendritic cells, lymphocytes and specific cell types at immune- privileged sites. It inactivates granzyme B, a natural occurring inducer of programmed cell death. As such, Spi-6 functions as anti-apoptotic protein. In cytotxic T cells (CTL), Spi-6 is required to protect clonal bursts (expansion) from granzyme B induced cell death. However, it is not required for the development of memory cells. Expression of SPI-6 is of crucial importance in the escape of several tumors from a CTL response and is, therefore, a parameter that influences the feasibility of CTL-mediated immunotherapy of cancer. The polyclonal antibody shows no crossreactivity with mouse proteins related to Spi-6. Aliases Cytoplasmic antiproteinase 3, serpin B9, PI-9 Immunogen Recombinant GST-Spi-6
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