anti-phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D) 抗体

Acts as a GTP specific dissociation inhibitor (GDI). 再加上,我们可以发phosphodiesterase 6D, CGMP-Specific, Rod, delta 蛋白 (9)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
PDE6D 363272  
PDE6D 5147 O43924
PDE6D 18582 O55057
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antibodies-online.cn销售最多的anti-phosphodiesterase 6D, CGMP-Specific, Rod, delta 抗体

Showing 10 out of 35 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
非结合性 ICC, IF, IHC (p), WB ICC/IF Image Immunofluorescence analysis of methanol-fixed HeLa, using PDE6D, antibody at 1:500 dilution. WB Image Sample (30 ug of whole cell lysate) A: MOLT4 , 12% SDS PAGE antibody diluted at 1:1000 100 μL 3至4个工作日
$466.18
详细
非结合性 WB Western blot analysis in A2058 cell line lysates (35ug/lane). Western blot analysis in mouse heart tissue lysates (35ug/lane). 400 μL 2至3个工作日
$515.63
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小鼠 非结合性 IF, ELISA, WB PDE6D monoclonal antibody (M06), clone 5C7 Western Blot analysis of PDE6D expression in HeLa . Immunofluorescence of monoclonal antibody to PDE6D on HeLa cell. [antibody concentration 20 ug/ml] 100 μg 11至12个工作日
$440.00
详细
Cow 非结合性 WB   100 μL 2至3个工作日
$289.00
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非结合性 WB Western blot analysis of extracts of various cell lines, using PDE6D antibody. 200 μL 12至14个工作日
$438.90
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非结合性 ICC, IHC, IHC (p), WB   100 μL 11至14个工作日
$537.17
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小鼠 非结合性 ICC, IF, IHC, IHC (fro), WB   100 μg 11至14个工作日
$639.83
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非结合性 ELISA, WB   200 μL 11至16个工作日
$658.43
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非结合性 IF/ICC, IHC (fp), WB   100 μL 6至8个工作日
$431.20
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Alkaline Phosphatase (AP) ELISA, WB   200 μL 11至14个工作日
$1,101.83
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引用最多的anti-phosphodiesterase 6D, CGMP-Specific, Rod, delta 抗体

  1. Human Polyclonal PDE6D Primary Antibody for IHC, IHC (p) - ABIN4344439 : Thomas, Wright, Le Corre, Micalizzi, Romani, Abhyankar, Saada, Perrault, Amiel, Litzler, Filhol, Elkhartoufi, Kwong, Casanova, Boddaert, Baehr, Lyonnet, Munnich, Burglen, Chassaing, Encha-Ravazi et al.: A homozygous PDE6D mutation in Joubert syndrome impairs targeting of farnesylated INPP5E protein to the primary cilium. ... in Human mutation 2014 (PubMed)

更多抗phosphodiesterase 6D, CGMP-Specific, Rod, delta的相互作用对抗体

Human phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D) interaction partners

  1. PDE6delta binds selectively to the C-terminus of RPGR and that this interaction is critical for RPGR's localization to cilia.

  2. Studies indicate that the binding of UNC119 and PDE6D, to the lipid-modified ciliary cargo and the specific release of the cargo in the cilia by the ciliary small G-protein Arl3 in a GTP-dependent manner.

  3. Study identifies PDE6D as a novel Joubert syndrome gene and provides the first evidence of prenyl-binding-dependent trafficking in ciliopathies.

  4. RPGR is acting as a scaffold protein recruiting cargo-loaded PDE6D and Arl3 to release lipidated cargo into cilia.

  5. findings indicate that ARL13B, INPP5E, PDE6D, and CEP164 form a distinct functional network that is involved in JBTS and NPHP but independent of the ones previously defined by NPHP and MKS proteins

  6. Data show that PDEdelta activity augments K/Hras signalling by enriching Ras at the plasma membrane.

Cow (Bovine) phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D) interaction partners

  1. Results suggest that PrBP/delta exclusively interacts with the soluble fraction of PDE6.

  2. The modest levels of basal activity exhibited by PDE6 purified from bovine rod outer segments (ROS) indicate that the inhibitory gamma subunit of PDE6 may not be tightly bound to PDE6 catalytic sites.

  3. PDEdelta functions as a prenyl-binding protein interacting with multiple prenylated proteins in retinal rods.

Mouse (Murine) phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D) interaction partners

  1. It postulates a three-step mechanism regulating ciliary localization of INPP5E, consisting of farnesylation- and PDE6delta-mediated targeting, INPP5E-PDE6delta complex diffusion into the cilium with transfer to the IFT system, and retention inside cilia.

  2. the affinity to PDE6delta and the release by Arl2/3 in addition to a retention signal are the determinants for cargo sorting and enrichment at its destination.

  3. Knockout of Unc119 partially reversed the transport defect of GRK1 in cone photoreceptors caused by deletion of Pde6d.

  4. absence of PrBP/delta in retina impairs transport of prenylated proteins, particularly rhodopsin kinase 1 and cone PDE, to rod and cone outer segments

phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D) 抗原简介

蛋白简介

Acts as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude and does so by decreasing the nucleotide dissociation rate. Stabilizes Arl3-GTP by decreasing the nucleotide dissociation (By similarity).

Gene names and symbols associated with PDE6D

  • phosphodiesterase 6D (Pde6d) 抗体
  • phosphodiesterase 6D (PDE6D) 抗体
  • phosphodiesterase 6D, cGMP-specific, rod, delta (pde6d) 抗体
  • phosphodiesterase 6D, cGMP-specific, rod, delta (Pde6d) 抗体
  • AI841218 抗体
  • PDE6D 抗体
  • PDED 抗体
  • PrBP/delta 抗体
  • zgc:92605 抗体

Protein level used designations for PDE6D

retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta , phosphodiesterase 6D, cGMP-specific, rod, delta , Retinal rod rhodopsin-sensitive cGMP 3,5-cyclic phosphodiesterase subunit delta , phosphodiesterase 6D , GMP-PDE delta , protein p17 , cGMP-phosphodiesterase delta subunit , pde6D gene for cGMP-phosphodiesterase delta subunit

GENE ID SPECIES
363272 Rattus norvegicus
424932 Gallus gallus
436981 Danio rerio
738319 Pan troglodytes
100286589 Salmo salar
100344476 Oryctolagus cuniculus
5147 Homo sapiens
281976 Bos taurus
403781 Canis lupus familiaris
18582 Mus musculus
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