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USP8 蛋白

Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation.

5 results:

Ubiquitin Specific Peptidase 8 (USP8) (AA 1-1118) protein (His tag) Protein

USP8 宿主: 人 资源: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
产品编号 ABIN3096238
$14,592.92
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping 发货至: 美国
70个工作日

Ubiquitin Specific Peptidase 8 (USP8) (AA 777-1118) protein (T7 tag,His tag) Protein

USP8 宿主: 人 资源: 大肠杆菌(E. Coli) Recombinant ≥ 92 % ELISA, IP, SDS, WB
产品编号 ABIN6237081
$410.00
加上运输费 $45.00
50 μg (More quantities available)
local_shipping 发货至: 美国
15至18个工作日

Ubiquitin Specific Peptidase 8 (USP8) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag) Protein

USP8 宿主: 人 资源: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
产品编号 ABIN2734893
$888.80
Plus shipping costs $45.00 and $24.00 dry ice
20 μg
local_shipping 发货至: 美国
11个工作日

Ubiquitin Specific Peptidase 8 (USP8) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag) Protein

USP8 宿主: 人 资源: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
产品编号 ABIN2735146
$888.80
Plus shipping costs $45.00 and $24.00 dry ice
20 μg
local_shipping 发货至: 美国
11个工作日

Ubiquitin Specific Peptidase 8 (USP8) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag) Protein

USP8 宿主: 人 资源: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
产品编号 ABIN2735145
$932.80
Plus shipping costs $45.00 and $24.00 dry ice
20 μg
local_shipping 发货至: 美国
11个工作日
  • 类型 Protein
    • Protein
  • 抗原 Ubiquitin Specific Peptidase 8 (USP8)
    • Ubiquitin Specific Peptidase 8 (USP8)
    • Hemagglutinin (HA)
    • Ribosome Binding Factor A (RBFA)
    • Tumor Necrosis Factor alpha (TNF)
    • S-Adenosyl-Methionine Synthase (METK)
    • Interleukin 6 (IL6)
    • Interferon gamma (IFNG)
    • Hemoglobin beta (HBB)
    • Triosephosphate Isomerase 1 (TPI1)
    • Thymidylate Kinase (Tmk)
    • Interleukin 4 (IL4)
    • Interleukin 1, beta (IL1B)
    • Interleukin 2 (IL2)
    • Uracil-DNA Glycosylase (UNG)
    • Growth Hormone 1 (GH1)
    • Lipoyl synthase lipA
    • Fibroblast Growth Factor 2 (Basic) (FGF2)
    • Interleukin 10 (IL10)
    • KIT Ligand (KITLG)
    • Malate Dehydrogenase (MDH)
    • Insulin-Like Growth Factor 1 (IGF1)
    • Epidermal Growth Factor (EGF)
    • Leptin (LEP)
    • Interleukin 8 (IL8)
    • Interleukin 3 (IL-3)
    • Myoglobin (MB)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1)
    • Hemoglobin, alpha 1 (HBA1)
    • phosphatidylserine Decarboxylase (PISD)
    • Interleukin 1 alpha (IL1A)
    • Prolactin (PRL)
    • Interleukin 13 (IL13)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • Albumin (ALB)
    • CD40 Ligand (CD40LG)
    • Chemokine (C-X-C Motif) Ligand 12 (CXCL12)
    • Aspartate Carbamoyltransferase (PYRB)
    • Phosphoglucosamine Mutase (GLMM)
    • Porphobilinogen Deaminase (HEMC)
    • beta-2-Microglobulin (B2M)
    • Interleukin 15 (IL15)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • Chemokine (C-C Motif) Ligand 2 (CCL2)
    • Gp120
    • Adiponectin (ADIPOQ)
    • Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2)
    • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    • Fibroblast Growth Factor 1 (Acidic) (FGF1)
    • Interleukin 33 (IL33)
    • Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1)
  • 应用范围
    • Antibody Production (AbP)
    • Functional Studies (Func)
    • Protein Interaction (PI)
    • Standard (STD)
    • ELISA
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • Immunoprecipitation (IP)
    • Crystallization (Crys)
  • 适用
  • 图像
  • 抗体来源
    • HEK-293 Cells
    • 大肠杆菌(E. Coli)
    • Insect Cells
  • 抗原表位
    • AA 1-1118
    • AA 777-1118
    • Transcript Variant 1
    • Transcript Variant 2
    • Transcript Variant 3
  • 标记
    • 非结合性
    • Myc-DYKDDDDK Tag
    • His tag
    • T7 tag,His tag
  • 蛋白类型
    • Recombinant
  • Format
    • Liquid

蛋白简介USP8

蛋白简介

Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. Converts both 'Lys-48' an 'Lys-63'-linked ubiquitin chains. Catalytic activity is enhanced in the M phase. Involved in cell proliferation. Required to enter into S phase in response to serum stimulation. May regulate T-cell anergy mediated by RNF128 via the formation of a complex containing RNF128 and OTUB1. Probably regulates the stability of STAM2 and RASGRF1. Regulates endosomal ubiquitin dynamics, cargo sorting, membrane traffic at early endosomes, and maintenance of ESCRT-0 stability. The level of protein ubiquitination on endosomes is essential for maintaining the morphology of the organelle. Deubiquitinates EPS15 and controles tyrosine kinase stability. Removes conjugated ubiquitin from EGFR thus regulating EGFR degradation and downstream MAPK signaling. Involved in acrosome biogenesis through interaction with the spermatid ESCRT-0 complex and microtubules. Deubiquitinates BIRC6/bruce and KIF23/MKLP1.

Gene names and symbols associated with USP8

  • ubiquitin carboxyl-terminal hydrolase 8 (LOC9310109) 抗体
  • ubiquitin carboxyl-terminal hydrolase 8 (MGYG_00369) 抗体
  • ubiquitin specific peptidase 8 (USP8) 抗体
  • ubiquitin specific peptidase 8 (Usp8) 抗体
  • AI574262 抗体
  • AW557536 抗体
  • HumORF8 抗体
  • mKIAA0055 抗体
  • Ubpy 抗体

Protein level used designations for USP8

ubiquitin carboxyl-terminal hydrolase 8 , ubiquitin-specific-processing protease 8 , ubiquitin specific peptidase 8 , ubiquitin carboxyl-terminal hydrolase 8-like , deubiquitinating enzyme 8 , hUBPy , ubiquitin isopeptidase Y , ubiquitin specific protease 8 , ubiquitin thioesterase 8 , ubiquitin thiolesterase 8 , putative deubiquitinating enzyme

GENE ID SPECIES
9310109 Arabidopsis lyrata subsp. lyrata
10031598 Arthroderma gypseum CBS 118893
100408559 Callithrix jacchus
100437819 Pongo abelii
9101 Homo sapiens
296121 Rattus norvegicus
84092 Mus musculus
100157546 Sus scrofa
415451 Gallus gallus
100351436 Oryctolagus cuniculus
100720255 Cavia porcellus

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