Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) ELISA试剂盒

The protein encoded by TNFSF18 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. 再加上,我们可以发Tumor Necrosis Factor (Ligand) Superfamily, Member 18 抗体 (177)Tumor Necrosis Factor (Ligand) Superfamily, Member 18 蛋白 (39)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
TNFSF18 240873 Q7TS55
TNFSF18 8995 Q9UNG2
大鼠 TNFSF18 TNFSF18 364031  
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产品编号 适用 灵敏度 范围 图像 规格 供应商 交付 价格 详细
小鼠 10pg/mL 31.2-2000 pg/mL Mouse TNFSF18/GITRL PicoKine ELISA Kit standard curve 96 Tests Log in to see 4至6个工作日
25 pg/mL 25-10000 pg/mL 96 Tests Log in to see 2至3个工作日
小鼠 4 pg/mL 4.1 pg/mL - 1000 pg/mL   96 Tests Log in to see 5至8个工作日
20 pg/mL 40.9 pg/mL - 10000 pg/mL   96 Tests Log in to see 5至8个工作日

引用最多的Tumor Necrosis Factor (Ligand) Superfamily, Member 18 ELISA试剂盒

  1. Human TNFSF18 ELISA Kit for Sandwich ELISA - ABIN625249 : Gan, Feng, Gu, Tan, Sun, Lv, Zhang: Correlation of increased blood levels of GITR and GITRL with disease severity in patients with primary Sjögren's syndrome. in Clinical & developmental immunology 2013 (PubMed)
    Show all 2 Pubmed References

适于 Tumor Necrosis Factor (Ligand) Superfamily, Member 18 相互作用对的更多 ELISA 试剂盒

Mouse (Murine) Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) interaction partners

  1. the upregulation of IFN-beta in DCs induces the up-regulation of coinhibitory molecules B7H1 and GITRL, which cause an impaired activation of naive Ag-specific T cells

  2. GITRL expressed on macrophages drives cytokine release and T cell activation, resulting in neuropathic pain via GITR-dependent actions. The GITRL-GITR pathway might represent a novel target for the treatment of neuropathic pain.

  3. Down-regulation of GITRL enhances CD8 T cell responses to chronic lymphocytic choriomeningitis virus.

  4. Sjogren's syndrome-like autoimmune sialadenitis in MRL-Faslpr mice is associated with expression of glucocorticoid-induced TNF receptor-related protein (GITR) ligand and 4-1BB ligand.

  5. GITRL triggering in endothelial cells increases leukocyte adhesion and transmigration.

  6. The B7H1 and GITRL molecules may play an important role in TGF-beta-induced Treg expansion of lung cancer microenvironment.

  7. results demonstrate that enhanced GITR/GITRL interactions have a pleiotropic role on the regulation of T-cell responses

  8. B cell expression of GITRL induced Treg proliferation, maintaining their numbers above a threshold required for the prevention of autoimmunity.

  9. Findings suggest GITRL could enhance the immune stimulation of DC and might facilitate the potential development of DCs-based anti-tumor therapies.

  10. GITRL-dependent expansion of Treg within the cornea is one mechanism underlying immune privilege in corneal allografts.

  11. GITR and GITRL are functionally expressed on brain microglia and that the stimulation of GITRL can induce inflammatory activation of microglia. The GITR/GITRL system may play an important role in neuroinflammation.

  12. TRAIL- and GITRL-activated pathways synergise in the development of SCI-related inflammatory damage.

  13. GITROL ligation of the costimulatory molecule GITR on Tregs inhibits their ability to promote graft survival. Blocking GITRL with a soluble GITR fusion protein prolongs graft survival.

  14. the GITR/GITRLigand pathway has a key role in the development of murine autoimmune diabetes

  15. glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells

  16. A soluble form of mouse GITR ligand (sGITR-L) induces GITR-dependent NF-kappa B activation and blocks in vitro suppression mediated by both resting and preactivated polyclonal and antigen-specific regulatory T (Treg) cells.

  17. GITR-L provides an important signal for CD25- T cells, rendering them resistant to CD25+ -mediated regulation at the initiation of the immune response.

  18. specific oligomeric forms of GITRL may be used as a means to differentially control GITR receptor signaling in diverse cells

  19. the unique structural and biochemical behavior of mouse GITRL, along with the unusual domain organization of murine GITR, support a previously unrecognized mechanism for signaling within the TNF superfamily

  20. GITRL-costimulation augments both effector and regulatory functions of CD4(+) T cells.

Human Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) interaction partners

  1. Cultured HCN-2 neurons were incubated at different times with GITRL and/or TRAIL, and thereafter nucleic acid and protein expression were measured. HCN-2 cells do not express GITRL mRNA, but the latter is induced after treatment with TRAIL. Cells did not express the GITRL receptor GITR mRNA, neither in control cultures, nor after treatment with TRAIL. TRAIL, when associated to GITRL, exerted additive toxic effects.

  2. GITRL levels are significantly elevated in rheumatoid arthritis serum and synovial fluid and are positively correlated with autoantibody production in rheumatoid arthritis, suggesting a role of GITRL in the development of rheumatoid arthritis.

  3. GITRL modulates the activities of p38 MAPK and STAT3 to promote Th17 cell differentiation in autoimmune arthritis.

  4. An increase in GITRL may impair the balance of Th17/Treg, and contribute to the pathopoiesis of Hashimoto's thyroiditis.

  5. Our findings indicate the possible involvement of GITR-GITRL pathway in the pathogenesis of pSS.

  6. Serum GITRL levels were higher in SLE patients.

  7. Glucocorticoid-induced TNF-related ligand (GITRL) confers pseudoexpression to tumor cells by platelets, which results in GITRL expression by megakaryocytes and their platelet progeny.

  8. observation suggests a link between cytokine-regulated keratinocyte GITRL expression and its role in inflammatory responses in AD

  9. GITRL upregulation induced by IFN-beta on dendritic cells downregulates CTLA-4 on regulatory T (Treg) cells, facilitating proliferation of anergic Treg cells in multiple sclerosis treatment of multiple sclerosis patients.

  10. Although GITR transgene costimulation can therapeutically enhance T helper (Th) type 2 cell responses, GITR-GITR ligand interactions are not required for development of Th2-mediated resistance or pathology.

  11. GITRL expression on Kupffer cells may mediate acute rejection in liver transplantation

  12. The incorporation of an isoleucine zipper motif could markedly improve the costimulation of hsGITRL.

  13. Upregulation by proinflammatory cytokines suggests GITRL may play important role in ocular immunity. High level of constitutive GITRL expression on photoreceptor inner segments suggests photoreceptors participate in regulation of ocular inflammation.

  14. Regulates ossteoclasst genersation and substantiate the major role played by the endothelium in bone physiology.

  15. Using a GITRL-transfected cell line, we demonstrate that GITRL promotes NK cell cytotoxicity and IFN-gamma production.

  16. GITRL could be a potential candidate for regulation of the ocular immune privilege and the balance between immune privilege and inflammation

  17. Since regulatory T-cells are localized in the vicinity of GITRL-expressing cells in atopic dermatitis skin, the GITR/GITRL interaction may serve to perpetuate the inflammation locally.

  18. Constitutive expression of GITRL by tumor cells diminishes natural killer cell antitumor immunity.

  19. although huGITRL is not capable of alleviating Treg suppression of responder T cells, huGITRL overexpression on monocyte-derived DC enhances their capacity to induce antigen-specific T cell responses

  20. These observations raise the possibility that the GITRL-mediated inflammatory activation of macrophages is involved in the pathogenesis of inflammatory diseases.

Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) 抗原简介

Antigen Summary

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.

Gene names and symbols associated with TNFSF18

  • tumor necrosis factor (ligand) superfamily, member 18 (Tnfsf18) 抗体
  • TNF superfamily member 18 (TNFSF18) 抗体
  • TNF superfamily member 18 (Tnfsf18) 抗体
  • AITRL 抗体
  • GITRL 抗体
  • hGITRL 抗体
  • TL6 抗体
  • TNLG2A 抗体

Protein level used designations for TNFSF18

GITR ligand , glucocorticoid-induced TNF-related ligand , glucocorticoid-induced-tumor necrosis factor receptor ligand , tumor necrosis factor ligand superfamily member 18 , AITR ligand , activation-inducible TNF-related ligand , glucocorticoid-induced TNFR-related protein ligand , tumor necrosis factor (ligand) superfamily, member 18 , tumor necrosis factor ligand 2A , tumor necrosis factor superfamily member 18

240873 Mus musculus
8995 Homo sapiens
364031 Rattus norvegicus
100855912 Canis lupus familiaris
100060504 Equus caballus
768081 Bos taurus
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