anti-Solute Carrier Family 7 (Amino Acid Transporter Light Chain, Y+L System), Member 7 (Slc7a7) 抗体

The protein encoded by Slc7a7 is the light subunit of a cationic amino acid transporter. 再加上,我们可以发Solute Carrier Family 7 (Amino Acid Transporter Light Chain, Y+L System), Member 7 试剂盒 (16)Solute Carrier Family 7 (Amino Acid Transporter Light Chain, Y+L System), Member 7 蛋白 (4)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
Slc7a7 9056 Q9UM01
Slc7a7 83509 Q9R0S5
Slc7a7 20540 Q9Z1K8
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antibodies-online.cn销售最多的anti-Solute Carrier Family 7 (Amino Acid Transporter Light Chain, Y+L System), Member 7 抗体

Showing 10 out of 18 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-SLC7A7 Antibody Titration:  0.2-1 ug/ml  Positive Control:  PANC1 cell lysate Host:  Rabbit  Target Name:  SLC7A7  Sample Type:  Human Fetal Heart  Antibody Dilution:  1.0ug/ml 100 μL 2至3个工作日
$319.00
详细
Cow 非结合性 IHC, IHC (p), WB Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested. 100 μL 11至14个工作日
$727.83
详细
山羊 非结合性 ELISA, WB   100 μg 6至7个工作日
$429.84
详细
小鼠 非结合性 ELISA Detection limit for recombinant GST tagged SLC7A7 is approximately 0.1ng/ml as a capture antibody. 100 μg 11至12个工作日
$440.00
详细
小鼠 非结合性 WB Western Blot analysis of SLC7A7 expression in transfected 293T cell line by SLC7A7 MaxPab polyclonal antibody.Lane1:SLC7A7 transfected lysate(56.21 KDa).Lane2:Non-transfected lysate. SLC7A7 MaxPab polyclonal antibody. Western Blot analysis of SLC7A7 expression in rat brain. 50 μg 11至12个工作日
$440.00
详细
非结合性 WB SLC7A7 antibody used at 1 ug/ml to detect target protein. 50 μg 9至11个工作日
$449.29
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Biotin ELISA   100 μg 11至16个工作日
$426.40
详细
FITC ELISA   100 μg 11至16个工作日
$426.40
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HRP ELISA   100 μg 11至16个工作日
$426.40
详细
非结合性 ELISA, IF/ICC, IHC, WB   100 μg 11至16个工作日
$426.40
详细

引用最多的anti-Solute Carrier Family 7 (Amino Acid Transporter Light Chain, Y+L System), Member 7 抗体

  1. Human Polyclonal Slc7a7 Primary Antibody for WB - ABIN522495 : Barilli, Rotoli, Visigalli, Bussolati, Gazzola, DallAsta: Arginine transport in human monocytic leukemia THP-1 cells during macrophage differentiation. in Journal of leukocyte biology 2011 (PubMed)

更多抗Solute Carrier Family 7 (Amino Acid Transporter Light Chain, Y+L System), Member 7的相互作用对抗体

Human Solute Carrier Family 7 (Amino Acid Transporter Light Chain, Y+L System), Member 7 (Slc7a7) interaction partners

  1. SLC7A7 gene detection showed three pathogenic mutations in these children, namely c.1387delG(p.V463CfsX56), c.1215G>A(p.W405X) and homozygous c.625+1G>A

  2. this study shows that downregulation of SLC7A7 triggers an inflammatory phenotype in human macrophages and airway epithelial cells

  3. SLC7A7 overexpression decreased the apoptosis rate, increased the proportion of cells in the G1 phase, decreased the proportion of G2 cells, and significantly increased cell migration and invasion and increased intracellular arginine would activate mTOR, and induce apoptosis in SLC7A7 knockdown Jurkat cells.

  4. Confirmed by mRNA and protein expression, the amino acid transporters SLC7A7 and SLC38A5 showed marked differences between controls and intrauterine growth restriction/pre-eclampsia and were regulated by both diseases. In contrast, ABCA1 may play an exclusive role in the development of pre-eclempsia.

  5. At present, 51 kinds of SLC7A7 gene mutations causing lysinuric protein intolerance have been found worldwide, including insert (C.1384-1385 ins ACTA), delete (C.1185-1188 del TTCT) and point mutations (P.R410X, P.Y457X, P.R 468X, P.L124p, etc).3, 4 In our cases, there were two heterozygous mutations in the SLC7A7 gene of the two sisters: C.1387 del C and IVS4+1C>T, which has never been reported worldwide.

  6. The study reports a significant association between SLC7A7 rs12436190 and the risk of glioma in a Chinese population.

  7. the 1471 delTTCT mutation was identified in exon 9 in the homozygous state for all Tunisian patients with lysinuric protein Intolerance; The 1471 deITTCT mutation seems to be a common mutation of Tunisian population

  8. heteromerization of y+LAT1 and 4F2hc within the cell is not disrupted by any of the tested LPI mutations

  9. SLC7A7 genetic variants are associated with increase risk for glioma in a Chinese population.

  10. SLC7A7 plays a critical role in glioblastoma carcinogenesis and overexpression of SLC7A7 is correlated with worse outcomes in patients

  11. SLC7A7/y+LAT1 mutations lead to a defective phenotype of macrophages resulting in lysinuric Protein Intolerance.

  12. during differentiation of human monocytes from peripheral blood, SLC7A7 mRNA and system y(+)L activity are increased

  13. novel SLC7A7 mutations in patients with lysinuric protein intolerance

  14. expression levels and putative 5' promoter elements of the SLC7A7 gene

  15. putative multiheteromeric structure of both [4F2hc/y(+)LAT-1] and [4F2hc/y(+)LAT-2], and the interference between y(+)LAT-1 and y(+)LAT-2 proteins may have a role in the pathogenesis of lysinuric protein intolerance

  16. mutations of the SLC7A7 gene may have a role in lysinuric protein intolerance

  17. identified a novel alternative, TATA-box-containing promoter that plays a role in the tissue-specific regulation of SLC7A7 gene expression

  18. Mutation in the SLC7A7 gene is associated with lysinuric protein intolerance

  19. A review of the current knowledge of SLC7A7 mutations and their role in LPI pathogenesis.

  20. results suggest genomic rearrangement of SLC7A7 play more important role in lysinuric protein intolerance than has been reported; 3' region AluY repeat could be a recombination hot spot as it is involved in 38% of SLC7A7 rearranged chromosomes described

Mouse (Murine) Solute Carrier Family 7 (Amino Acid Transporter Light Chain, Y+L System), Member 7 (Slc7a7) interaction partners

  1. The expression of Mct8 and L-type amino acid transporters Lat2 and Lat1 are determined in brain neurons during development.

  2. Increased LAT1 expression can be induced by lipid oxidation products relevant to inflammatory responses in atherogenesis. LAT1 mediates lysophosphatidylcholine-enhanced cytokine production by endothelial cells.

  3. selective regulation of SNAT3 and y(+)LAT1 expression may serve a major role in the renal adaptation to acid secretion and thus for systemic acid-base balance.

  4. The Slc7a7(-/-) mouse displayed intrauterine growth restriction, leading to neonatal lethality. After heavy protein ingestion, the surviving adult animals presented metabolic derangement consistent with lysinuric protein intolerance.

  5. System L functions as influx and/or efflux transport machinery displaying a greater propensity for the outward transport of large and small neutral amino acids.

  6. LAT1, and LAT2 mRNAs were detected in fetal and postnatal femurs and in MC3T3-E1 cells, while OATP1 and NTCP mRNAs were not.

Solute Carrier Family 7 (Amino Acid Transporter Light Chain, Y+L System), Member 7 (Slc7a7) 抗原简介

蛋白简介

The protein encoded by this gene is the light subunit of a cationic amino acid transporter. This sodium-independent transporter is formed when the light subunit encoded by this gene dimerizes with the heavy subunit transporter protein SLC3A2. This transporter is found in epithelial cell membranes where it transfers cationic and large neutral amino acids from the cell to the extracellular space. Defects in this gene are a cause of lysinuric protein intolerance (LPI). Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with Slc7a7

  • solute carrier family 7 member 7 (SLC7A7) 抗体
  • solute carrier family 7 member 7 (Slc7a7) 抗体
  • solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 (Slc7a7) 抗体
  • AI790233 抗体
  • LAT3 抗体
  • LPI 抗体
  • MOP-2 抗体
  • my+lat1 抗体
  • y+LAT-1 抗体
  • y+LAT1 抗体

Protein level used designations for Slc7a7

Y+L amino acid transporter 1 , monocyte amino acid permease 2 , solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 , y(+)L-type amino acid transporter 1 , solute carrier family 7 member 7 , y+LAT-1 , y+LAT1

GENE ID SPECIES
9056 Homo sapiens
83509 Rattus norvegicus
20540 Mus musculus
anti-Solute Carrier Family 7 (Amino Acid Transporter Light Chain, Y+L System), Member 7 (Slc7a7) 抗体 精选生产商
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