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anti-SMCR8 抗体

Component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy.

3 results:

anti-SMCR8 抗体 (Smith-Magenis Syndrome Chromosome Region, Candidate 8) Primary Antibody

SMCR8 适用: 人 IF, IHC (p), WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5588427
$577.33
加上运输费 $45.00
100 μL
local_shipping 发货至: 美国
11至12个工作日

anti-SMCR8 抗体 (Smith-Magenis Syndrome Chromosome Region, Candidate 8) (C-Term) Primary Antibody

SMCR8 适用: 人, 大鼠, 犬, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2791916
$389.00
加上运输费 $45.00
100 μL
local_shipping 发货至: 美国
2至3个工作日

anti-SMCR8 抗体 (Smith-Magenis Syndrome Chromosome Region, Candidate 8) (AA 841-890) Primary Antibody

SMCR8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6753676
$551.83
加上运输费 $45.00
100 μL
local_shipping 发货至: 美国
11至14个工作日
  • 类型 Primary
    • Primary
  • 抗原 Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
    • Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
    • Histone 3 (H3)
    • Tumor Protein P53 (TP53)
    • Epidermal Growth Factor Receptor (EGFR)
    • Mast/stem Cell Growth Factor Receptor (KIT)
    • Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
    • CD4 Molecule (CD4)
    • tau Protein
    • Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2)
    • Tumor Necrosis Factor alpha (TNF)
    • V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1)
    • Interferon gamma (IFNG)
    • Albumin (ALB)
    • BCL2-Associated Agonist of Cell Death (BAD)
    • Estrogen Receptor 1 (ESR1)
    • Nuclear Factor-KB P65 (NFkBP65)
    • V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1)
    • Tuberous Sclerosis 2 (TSC2)
    • CD8a Molecule (CD8A)
    • B-Cell CLL/lymphoma 2 (BCL2)
    • Platelet/endothelial Cell Adhesion Molecule (PECAM1)
    • CD19 Molecule (CD19)
    • CD3e Molecule, epsilon (CD3-TCR Complex) (CD3E)
    • Integrin alpha M (ITGAM)
    • CD8
    • Hemagglutinin (HA)
    • Histone H4
    • CD44
    • Interleukin 6 (IL6)
    • Epithelial Cell Adhesion Molecule (EPCAM)
    • Myc Proto-Oncogene protein (MYC)
    • Interleukin 2 Receptor, alpha (IL2RA)
    • Jun Proto-Oncogene (JUN)
    • Mucin 1, Cell Surface Associated (MUC1)
    • CD5 Molecule (CD5)
    • Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1)
    • Amyloid beta (A4) Precursor Protein (APP)
    • CD3
    • C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
    • Glial Fibrillary Acidic Protein (GFAP)
    • Vimentin (VIM)
    • Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR)
    • CD14
    • Interleukin 2 (IL2)
    • Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1)
    • PTK2 Protein tyrosine Kinase 2 (PTK2)
    • Tuberous Sclerosis 1 (TSC1)
    • CD34
    • alpha-Fetoprotein (AFP)
    • Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1)
    • Keratin 18 (KRT18)
  • 应用范围
    • Western Blotting (WB)
    • Immunofluorescence (IF)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 适用
    • 大鼠
  • 图像
  • 抗体来源
  • 克隆形成能力
    • Polyclonal
  • 抗原表位
    • AA 841-890
    • C-Term
  • 抗体亚型
    • IgG
  • Format
    • Liquid
    • Lyophilized

SMCR8 抗原简介

蛋白简介

Component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy. In the complex, C9orf72 and SMCR8 probably constitute the catalytic subunits that promote the exchange of GDP to GTP, converting inactive GDP-bound RAB8A and RAB39B into their active GTP-bound form, thereby promoting autophagosome maturation. The C9orf72-SMCR8 complex also acts as a negative regulator of autophagy initiation by interacting with the ATG1/ULK1 kinase complex and inhibiting its protein kinase activity. {ECO:0000250|UniProtKB:Q8TEV9}.

Gene names and symbols associated with SMCR8

  • Smith-Magenis syndrome chromosome region, candidate 8 (SMCR8) 抗体
  • Smith-Magenis syndrome chromosome region, candidate 8 homolog (human) (Smcr8) 抗体
  • Smith-Magenis syndrome chromosome region, candidate 8 (Smcr8) 抗体
  • Smith-Magenis syndrome chromosome region, candidate 8b (smcr8b) 抗体
  • 2310076G09Rik 抗体
  • AI642055 抗体
  • D030073L15Rik 抗体
  • RGD1564621 抗体
  • smcr8 抗体

Protein level used designations for SMCR8

Smith-Magenis syndrome chromosomal region candidate gene 8 protein , Smith-Magenis syndrome chromosomal region candidate gene 8 protein homolog , Smith-Magenis syndrome chromosome region, candidate 8 homolog , Smith-Magenis syndrome chromosomal region candidate gene 8 protein homolog B , guanine nucleotide exchange protein smcr8b , smith-Magenis syndrome chromosomal region candidate gene 8-B protein homolog

GENE ID SPECIES
140775 Homo sapiens
237782 Mus musculus
497918 Rattus norvegicus
407723 Danio rerio

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