anti-Nuclear Protein, Ataxia-Telangiectasia Locus (NPAT) 抗体

Required for progression through the G1 and S phases of the cell cycle and for S phase entry. 再加上,我们可以发和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
NPAT 315666  
NPAT 244879 Q8BMA5
NPAT 4863 Q14207
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Showing 6 out of 8 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
小鼠 非结合性 DB Left: NPAT staining. Right: Coomassie Blue staining of immunized recombinant protein. 50 μg 9至11个工作日
$259.57
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小鼠 非结合性 WB   50 μg 11至14个工作日
$581.17
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非结合性 WB   100 μL 2至3个工作日
$289.00
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非结合性 IF, IHC, IHC (p), IP   100 μL 11至14个工作日
$595.83
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小鸡 非结合性 IF, IHC, IHC (p), IP, WB   100 μL 11至14个工作日
$595.83
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小鼠 非结合性 DB, WB   50 μg 11至16个工作日
$378.71
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更多抗NPAT的相互作用对抗体

Mouse (Murine) Nuclear Protein, Ataxia-Telangiectasia Locus (NPAT) interaction partners

  1. NPAT links E2F to the activation of S-phase-specific histone gene transcription.

  2. Data indicate that the CDK2/cyclin E/p220(NPAT)/HINFP/histone gene signaling pathway at the G1/S phase transition is an essential, nonredundant cell cycle regulatory mechanism that is established early in embryogenesis.

Human Nuclear Protein, Ataxia-Telangiectasia Locus (NPAT) interaction partners

  1. Cpn10 has a role in the spatial regulation of NPAT signaling

  2. The conserved C-terminal domain shared by FLASH, YARP, and Mute recognizes the C-terminal sequence of NPAT orthologues, thus acting as a signal targeting proteins to histone locus bodies.

  3. Genetic variants of NPAT-ATM and AURKA are associated with an individual early adverse reaction in the gastrointestinal tract of patients with cervical cancer treated with pelvic radiation therapy

  4. NPAT is thus far the first gene implicated in nodular lymphocyte predominant Hodgkin lymphoma predisposition.

  5. NPAT is essential for histone mRNA 3' end processing and recruits CDK9 to replication-dependent histone genes.

  6. Results characterize the functional signals required for NPAT localization to the cell nucleus.

  7. NPAT links E2F to the activation of S-phase-specific histone gene transcription.

  8. the ability of p220 to promote S phase is independent of its ability to promote histone H4 transcription and p220 may link cyclin E/Cdk2 to multiple independent downstream functions

  9. OCA-S, the multicomponent Oct-1 coactivator, intercts with NPAT.

  10. p220 is an essential downstream component of the cyclin E/Cdk2 signaling pathway and functions to coordinate multiple elements of the G1/S transition.

  11. NPAT, together with CUL5 and PPP2R1B, is implicated in the deregulation of the cell-cycle and apoptosis regulators and in the pathogenesis of B-CLL.

  12. NPAT recruits the TRRAP-Tip60 complex to histone gene promoters to coordinate the transcriptional activation of multiple histone genes during the G(1)/S-phase transition

  13. HiNF-P/P220NPAT regulates expression of nonhistone targets that influence competency for cell cycle progression.

  14. Only the number of FLASH/NPAT histone gene locus bodies correlates with ploidy and only these organelles appear to be regulated during the cell cycle.

  15. Results suggest that cyclin-dependent kinase inhibitors selectively control stimulation of the histone H4 gene promoter by the p220(NPAT)/HiNF-P complex.

  16. The subnuclear organization of histone gene regulatory proteins and 3' end processing factors (NPAT/LSM10) of normal somatic and embryonic stem cells is compromised in selected human cancer cell types.

  17. Cyclin D2 and the CDK substrate p220(NPAT) are required for self-renewal of human embryonic stem cells.

NPAT 抗原简介

蛋白简介

Required for progression through the G1 and S phases of the cell cycle and for S phase entry. Activates transcription of the histone H2A, histone H2B, histone H3 and histone H4 genes (By similarity).

Gene names and symbols associated with NPAT

  • nuclear protein, co-activator of histone transcription (Npat) 抗体
  • nuclear protein, coactivator of histone transcription (NPAT) 抗体
  • protein NPAT (LOC489420) 抗体
  • nuclear protein, ataxia-telangiectasia locus (NPAT) 抗体
  • nuclear protein, ataxia-telangiectasia locus (npat) 抗体
  • protein NPAT (LOC100286556) 抗体
  • protein NPAT (LOC100402032) 抗体
  • protein NPAT (LOC100480887) 抗体
  • protein NPAT (LOC100540521) 抗体
  • protein NPAT (LOC100561473) 抗体
  • protein NPAT (LOC100627195) 抗体
  • nuclear protein in the AT region (Npat) 抗体
  • nuclear protein, ataxia-telangiectasia locus S homeolog (npat.S) 抗体
  • 6820401K01 抗体
  • AI427561 抗体
  • BB112559 抗体
  • DKFZp469B186 抗体
  • E14 抗体
  • E14/NPAT 抗体
  • im:6901964 抗体
  • NPAT-like 抗体
  • p220 抗体

Protein level used designations for NPAT

protein NPAT , nuclear protein in the AT region , nuclear protein, ataxia-telangiectasia locus , zmp:0000000655 , protein NPAT-like , E14 , nuclear protein of the ATM locus , nuclear protein of the ataxia telangiectasia mutated locus

GENE ID SPECIES
315666 Rattus norvegicus
418967 Gallus gallus
451529 Pan troglodytes
489420 Canis lupus familiaris
526583 Bos taurus
552973 Danio rerio
707873 Macaca mulatta
100286556 Salmo salar
100294539 Pongo abelii
100402032 Callithrix jacchus
100480887 Ailuropoda melanoleuca
100540521 Meleagris gallopavo
100561473 Anolis carolinensis
100627195 Sus scrofa
244879 Mus musculus
100037125 Xenopus laevis
4863 Homo sapiens
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