anti-Murine Retrovirus Integration Site 1 Homolog 抗体
MRVI1 is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV).
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anti-Murine Retrovirus Integration Site 1 Homolog (MRVI1) (N-Term) 抗体 Primary Antibody
anti-Murine Retrovirus Integration Site 1 Homolog (MRVI1) 抗体 Primary Antibody
anti-Murine Retrovirus Integration Site 1 Homolog (MRVI1) 抗体 Primary Antibody
anti-Murine Retrovirus Integration Site 1 Homolog (MRVI1) (AA 51-100) 抗体 Primary Antibody
Murine Retrovirus Integration Site 1 Homolog (MRVI1) 抗原简介
蛋白简介
This gene is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV). The encoded protein, which is found in the membrane of the endoplasmic reticulum, is similar to Jaw1, a lymphoid-restricted protein whose expression is down-regulated during lymphoid differentiation. This protein is a substrate of cGMP-dependent kinase-1 (PKG1) that can function as a regulator of IP3-induced calcium release. Studies in mouse suggest that MRV integration at Mrvi1 induces myeloid leukemia by altering the expression of a gene important for myeloid cell growth and/or differentiation, and thus this gene may function as a myeloid leukemia tumor suppressor gene. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, and alternative translation start sites, including a non-AUG (CUG) start site, are used.
Gene names and symbols associated with MRVI1
- MRV integration site 1 (Mrvi1) 抗体
- murine retrovirus integration site 1 homolog (MRVI1) 抗体
- BB115629 抗体
- IRAG 抗体
- JAW1L 抗体
- Ris1 抗体
Protein level used designations for MRVI1
JAW1-related protein MRVI1 , inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate , inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate , murine retrovirus integration site 1 protein , protein MRVI1 , retroviral integration site 1 , IP3R-associated cGMP kinase substrate , IP3 receptor associated cGMP kinase substrate
GENE ID | SPECIES |
---|---|
17540 | Mus musculus |
10335 | Homo sapiens |
281918 | Bos taurus |
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