电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

MRVI1 抗体 (N-Term)

MRVI1 适用: 人, 马, 小鼠, 兔, Cow, 犬, 豚鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2773963
发货至: 中国
  • 抗原 See all MRVI1 抗体
    MRVI1 (Murine Retrovirus Integration Site 1 Homolog (MRVI1))
    抗原表位
    • 1
    • 1
    N-Term
    适用
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 马, 小鼠, 兔, Cow, 犬, 豚鼠, 大鼠
    宿主
    • 3
    克隆类型
    • 3
    多克隆
    标记
    • 3
    This MRVI1 antibody is un-conjugated
    应用范围
    • 3
    • 1
    • 1
    Western Blotting (WB)
    序列
    LVNDQLPDIS ISEEDKKKNL ALLEEAKLVS ERFLTRRGRK SRSSPGDSPS
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against MRVI1. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human MRVI1
    Top Product
    Discover our top product MRVI1 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeat freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    MRVI1 (Murine Retrovirus Integration Site 1 Homolog (MRVI1))
    别名
    MRVI1 (MRVI1 产品)
    别名
    BB115629 antibody, Irag antibody, Ris1 antibody, IRAG antibody, JAW1L antibody, MRV integration site 1 antibody, murine retrovirus integration site 1 homolog antibody, Mrvi1 antibody, MRVI1 antibody
    背景
    This gene is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV). The encoded protein, which is found in the membrane of the endoplasmic reticulum, is similar to Jaw1, a lymphoid-restricted protein whose expression is down-regulated during lymphoid differentiation. This protein is a substrate of cGMP-dependent kinase-1 (PKG1) that can function as a regulator of IP3-induced calcium release. Studies in mouse suggest that MRV integration at Mrvi1 induces myeloid leukemia by altering the expression of a gene important for myeloid cell growth and/or differentiation, and thus this gene may function as a myeloid leukemia tumor suppressor gene. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, and alternative translation start sites, including a non-AUG (CUG) start site, are used.
    Protein Interaction Partner: MME, PRKG1, ITPR1,
    Protein Size: 803
    分子量
    88 kDa
    基因ID
    10335
You are here:
客服