anti-Mitogen-Activated Protein Kinase Kinase Kinase 10 (MAP3K10) 抗体

The protein encoded by MAP3K10 is a member of the serine/threonine kinase family. 再加上,我们可以发MAP3K10 蛋白 (7)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
MAP3K10 308463  
MAP3K10 4294 Q02779
MAP3K10 269881  
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antibodies-online.cn销售最多的anti-MAP3K10 抗体

Showing 10 out of 70 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB 100 μL Log in to see 2至3个工作日
非结合性 IHC, WB Immunohistochemical analysis of MLK2 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of MLK2 expression in HeLa (A), Raw264.7 (B), H9C2 (C) whole cell lysates. 200 μL Log in to see 13至14个工作日
非结合性 IHC (p), WB The anti-MLK2 Pab (ABIN392424) is used in Western blot to detect MLK2 in transfected COS7 cell lysate. Data is kindly provided by Drs. M.K. Barthwal and A. Rana from Texas A&M University, Health Science Center (Temple, TX). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10至11个工作日
非结合性 IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using MAP3K10 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
非结合性 EIA, IHC (p), WB 0.4 mL Log in to see 6至8个工作日
非结合性 WB 50 μg Log in to see 7至9个工作日
非结合性 IHC (p), WB Western blot analysis in K562 cell line lysates (35ug/lane). Mouse Map3k10 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded mouse skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 2至3个工作日
非结合性 ELISA, IHC   100 μL Log in to see 16 Days
非结合性 IHC, IHC (p), WB Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-MAP3K10 / MLK2 antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 200 μL Log in to see 11至14个工作日
非结合性 ELISA, IHC 200 μL Log in to see 12至14个工作日

引用最多的anti-MAP3K10 抗体

  1. Human Polyclonal MAP3K10 Primary Antibody for IHC (p), WB - ABIN392424 : Humphrey, Newcomb, Yu, Hao, Yu, Krajewski, Du, Jhala: Mixed lineage kinase-3 stabilizes and functionally cooperates with TRIBBLES-3 to compromise mitochondrial integrity in cytokine-induced death of pancreatic beta cells. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 Pubmed References


Human Mitogen-Activated Protein Kinase Kinase Kinase 10 (MAP3K10) interaction partners

  1. MST interaction with MOB1 (显示 MOBKL3 抗体) is not essential for development and tissue growth control.

  2. We identified a direct target of miR (显示 MLXIP 抗体)-155 as MAP3K10 in osteosarcoma

  3. MAP3K4 (显示 MAP3K4 抗体) is sufficiently mediate the TGFbeta (显示 TGFB1 抗体)-induced phosphorylation of p38 MAPK (显示 MAPK14 抗体) in MEFs and HaCaT cells.

  4. A novel and important role for MAP3K10 in the proliferation and chemoresistance of pancreatic ductal adenocarcinoma.

  5. This study showed that show that RUNX3 (显示 RUNX3 抗体) is a principal and evolutionarily conserved component of the MST pathway.

  6. Mechanism of MAP kinase (显示 MAPK1 抗体) activation by TNF (显示 TNF 抗体) requires Src (显示 SRC 抗体)-dependent activation of Vav (显示 VAV1 抗体), activation of Rac (显示 AKT1 抗体)/Cdc42 (显示 CDC42 抗体), and the engagement of the Rac (显示 AKT1 抗体)/Cdc42 (显示 CDC42 抗体) interaction site on MLK2 and 3.

  7. Data show that miR (显示 MLXIP 抗体)-181b contributed to proliferation of AML (显示 RUNX1 抗体) cells by targeting MLK2.

  8. MLK2 has a role in vesicle formation and endosome recycling by binding to clathrin

  9. demonstrate Alien-MLK2 interaction and also show that MLK2 is able to phosphorylate Alien; Alien, DAX-1 (显示 NR0B1 抗体) and thyroid hormone receptor (显示 THRA 抗体) mediated transcriptional silencing is strongly enhanced in the presence of active MLK2

  10. MLK2 and -3 are required for activation of JNK (显示 MAPK8 抗体) and p38 (显示 CRK 抗体) by ectopically expressed GCK (显示 GCK 抗体)

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase Kinase 10 (MAP3K10) interaction partners

  1. There is extensive functional redundancy between MLK1 (显示 MAP3K9 抗体) and MLK2, and the other member of the family, MLK3 (显示 KCNK7 抗体), none of which are required for survival in mouse.

  2. Mixed lineage kinase (显示 MAP3K12 抗体) phosphorylates transcription factor E47 (显示 TCF3 抗体) and inhibits TrkB (显示 NTRK2 抗体) expression to link neuronal death and survival pathways

MAP3K10 抗原简介


The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.

Gene names and symbols associated with MAP3K10

  • mitogen-activated protein kinase kinase kinase 10 (MAP3K10) 抗体
  • mitogen activated protein kinase kinase kinase 10 (Map3k10) 抗体
  • mitogen-activated protein kinase kinase kinase 10 (Map3k10) 抗体
  • mitogen-activated protein kinase kinase kinase 10 L homeolog (map3k10.L) 抗体
  • BC028668 抗体
  • BC046514 抗体
  • MEKK10 抗体
  • mlk2 抗体
  • MST 抗体
  • xmlk2 抗体

Protein level used designations for MAP3K10

mitogen-activated protein kinase kinase kinase 10 , mixed-lineage kinase 2 , MKN28 derived nonreceptor_type serine/threonine kinase , MKN28 kinase , mixed lineage kinase 2 , protein kinase MST , MKN28 derived nonreceptor_type , serine/threonine kinase

700477 Macaca mulatta
100017495 Monodelphis domestica
100067981 Equus caballus
100343621 Oryctolagus cuniculus
308463 Rattus norvegicus
4294 Homo sapiens
269881 Mus musculus
484504 Canis lupus familiaris
100521453 Sus scrofa
781037 Bos taurus
398612 Xenopus laevis
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