anti-Microspherule Protein 1 (MCRS1) 抗体

Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. 再加上,我们可以发MCRS1 试剂盒 (3)MCRS1 蛋白 (3)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
MCRS1 51812 Q99L90
MCRS1 300222  
MCRS1 10445 Q96EZ8
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antibodies-online.cn销售最多的anti-MCRS1 抗体

Showing 10 out of 51 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
非结合性 ELISA, WB Western blot analysis of MCRS1 using MCF7 whole cell lysates 100 μL 11至12个工作日
非结合性 WB Western blot analysis in HepG2 cell line lysates (35ug/lane). 400 μL 2至3个工作日
非结合性 IHC, WB Western blot analysis of extracts of various cells, using MCRS1 antibody. 100 μL 11至13个工作日
非结合性 IP Immunoprecipitation of MCRS1 transfected lysate using anti-MCRS1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with MCRS1 purified MaxPab mouse polyclonal antibody (B01P) . 100 μL 11至12个工作日
小鼠 非结合性 IF, IHC (p), WB Western Blot analysis of MCRS1 expression in transfected 293T cell line by MCRS1 MaxPab polyclonal antibody.Lane 1: MCRS1 transfected lysate(50.82 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of purified MaxPab antibody to MCRS1 on HeLa cell. [antibody concentration 10 ug/ml] 50 μg 11至12个工作日
非结合性 WB   100 μL 2至3个工作日
非结合性 WB Western blot analysis of extracts of various cell lines, using MCRS1 antibody (ABIN5975252) at 1/1000 dilution. 100 μL 11至16个工作日
非结合性 ELISA, WB   200 μL 11至16个工作日
非结合性 IHC, WB   100 μL 11至14个工作日
小鼠 非结合性 IF, IHC, IHC (p), WB   50 μg 11至14个工作日

引用最多的anti-MCRS1 抗体

  1. Human Polyclonal MCRS1 Primary Antibody for IF, IHC (p) - ABIN523843 : Xu, Zheng, Zhang, Zhao, Zhang, Wu, Wu, Wang, Wang, Zhang: MSP58 knockdown inhibits the proliferation of esophageal squamous cell carcinoma in vitro and in vivo. in Asian Pacific journal of cancer prevention : APJCP 2012 (PubMed)
    Show all 2 Pubmed References


Fruit Fly (Drosophila melanogaster) Microspherule Protein 1 (MCRS1) interaction partners

  1. Results suggest that dMCRS2 is required for loading of RNAP II complexes on the cyclin gene promoters.

Human Microspherule Protein 1 (MCRS1) interaction partners

  1. Authors show that Mps1 regulates chromosome alignment through MCRS1, a spindle assembly factor that controls the dynamics of the minus end of kinetochore microtubules. Mps1 binds and phosphorylates MCRS1.

  2. Study shows that MCRS1 binds to cytoplasmic dynein and contributes to the establishment of centriolar satellites and ciliogenesis.

  3. MSP58 downregulation suppressed the proliferation and invasion of renal cell carcinoma cells.

  4. MCRS1 is phosphorylated by the Aurora-A kinase in mitosis on Ser35/36.

  5. RINT-1 interacts with MSP58 and UBF within nucleoli and plays a role in ribosomal gene transcription.

  6. The immunoreactivity score (IRS) of MSP58 increased with tumor grade with grade IV gliomas exhibiting the highest expression and showed a highly significant positive correlation with the Ki-67 index (r = 0.65, P < 0.001).

  7. Suggest that MSP58 plays an important role in tumorigenesis and progression and may help predict the prognosis of gastric cancer patients.

  8. MCRS1 overexpression induced non-small cell lung cancer proliferation through the miR-155-Rb1 pathway and DNA copy-number amplification is one of the mechanisms underlying MCRS1 overexpression in non-small cell lung cancer.

  9. MSP58 subnuclear localization is regulated by two nuclear import signals, and proper subcellular localization of MSP58 is critical for its role in transcriptional regulation. A molecular mechanism controls nuclear and nucleolar localization of MSP58.

  10. BAP1 loss and MCRS1 down-regulation in renal cell carcinoma are associated with adverse clinicopathological features.

  11. MiR-129* down-regulation induced MCRS1 overexpression.

  12. High expression of MSP58 was also an independent unfavorable prognostic factor.

  13. MSP58 could suppress the transcription of hTERT promoter.

  14. MSP58 expression in hepatocellular carcinoma is closely related to the prognosis.

  15. Our results demonstrated MSP58 might serve as a novel prognostic marker for colorectal cancer

  16. MSP58 contributes to the tumorigenesis of neuroblastoma by promoting cell proliferation.

  17. RACGAP1 and MCRS1 overexpression in nonsmall-cell lung cancer.RACGAP1 and MCRS1 may be cancer-related genes in NSCLC.

  18. MSP58 depletion induced cell cycle arrest.

  19. Interaction between microspherule protein Msp58 and ubiquitin E3 ligase EDD regulates cell cycle progression.

  20. Our findings highlight new aspects of MSP58 in modulating cellular senescence and suggest that MSP58 has both oncogenic and tumor-suppressive properties.

MCRS1 抗原简介


Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity.

Gene names and symbols associated with MCRS1

  • Reduction in Cnn dots 5 (Rcd5) 抗体
  • microspherule protein 1 L homeolog (mcrs1.L) 抗体
  • microspherule protein 1 (mcrs1) 抗体
  • microspherule protein 1 (MCRS1) 抗体
  • microspherule protein 1 (CpipJ_CPIJ004521) 抗体
  • microspherule protein 1 (Tsp_07041) 抗体
  • microspherule protein 1 (Tsp_07058) 抗体
  • microspherule protein 1 (Tsp_06917) 抗体
  • microspherule protein 1 (Mcrs1) 抗体
  • C78274 抗体
  • CG1135 抗体
  • dMCRS1 抗体
  • dMCRS2 抗体
  • Dmel\\CG1135 抗体
  • ICP22BP 抗体
  • INO80Q 抗体
  • l(3)r0166 抗体
  • l(3)rG166 抗体
  • MCRS1 抗体
  • mcrs2 抗体
  • MSP58 抗体
  • P78 抗体
  • wu:fj97a11 抗体
  • zgc:66428 抗体
  • zgc:77376 抗体

Protein level used designations for MCRS1

CG1135-PA , Rcd5-PA , lethal (3) rG166 , reduction in Cnn dots 5 , microspherule protein 1 , microspherule protein 1-like , 58 kDa microspherule protein , nucleolar protein , INO80 complex subunit J , INO80 complex subunit Q , cell cycle-regulated factor (78 kDa) , cell cycle-regulated factor p78

38478 Drosophila melanogaster
380567 Xenopus laevis
406557 Danio rerio
451881 Pan troglodytes
477616 Canis lupus familiaris
549534 Xenopus (Silurana) tropicalis
710919 Macaca mulatta
100022253 Monodelphis domestica
100051964 Equus caballus
100394625 Callithrix jacchus
100471618 Ailuropoda melanoleuca
100561650 Anolis carolinensis
100600396 Nomascus leucogenys
6036210 Culex quinquefasciatus
10903334 Trichinella spiralis
10903352 Trichinella spiralis
10912195 Trichinella spiralis
51812 Mus musculus
300222 Rattus norvegicus
10445 Homo sapiens
514410 Bos taurus
426664 Gallus gallus
100343297 Oryctolagus cuniculus
100724960 Cavia porcellus
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