anti-Microspherule Protein 1 (MCRS1) 抗体

Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. 再加上,我们可以发MCRS1 试剂盒 (15)MCRS1 蛋白 (3)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
MCRS1 51812 Q99L90
MCRS1 300222  
MCRS1 10445 Q96EZ8
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Showing 10 out of 45 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 WB MCRS1 Antibody (N-term)  western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the MCRS1 antibody detected the MCRS1 protein (arrow). 400 μL Log in to see 10至11个工作日
非结合性 ELISA, WB Western blot analysis of MCRS1 using MCF7 whole cell lysates 100 μL Log in to see 11至12个工作日
非结合性 IHC, WB Western blot analysis of extracts of various cells, using MCRS1 antibody. 100 μL Log in to see 16 Days
非结合性 IP Immunoprecipitation of MCRS1 transfected lysate using anti-MCRS1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with MCRS1 purified MaxPab mouse polyclonal antibody (B01P) . 100 μL Log in to see 11至12个工作日
小鼠 非结合性 IF, IHC (p), WB Western Blot analysis of MCRS1 expression in transfected 293T cell line by MCRS1 MaxPab polyclonal antibody.<br><br>Lane 1: MCRS1 transfected lysate(50.82 KDa).<br>Lane 2: Non-transfected lysate.<br> Immunofluorescence of <u>purified</u> MaxPab antibody to MCRS1 on HeLa cell. [antibody concentration 10 ug/ml] 50 μg Log in to see 11至12个工作日
非结合性 ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: MCRS1 Antibody [NBP1-81615] - Staining of human testis shows strong nuclear positivity in cells in seminiferus ducts. Immunofluorescence: MCRS1 Antibody [NBP1-81615] - Immunofluorescent staining of human cell line MCF-7 shows positivity in nucleus but not nucleoli. 0.1 mL Log in to see 10至13个工作日
非结合性 WB   100 μL Log in to see 2至3个工作日
非结合性 WB Western blot analysis of extracts of various cell lines, using MCRS1 antibody (ABIN5975252) at 1/1000 dilution. 100 μL Log in to see 11至16个工作日
非结合性 ELISA, WB   200 μL Log in to see 11至16个工作日
非结合性 IHC, WB   100 μL Log in to see 7至9个工作日

引用最多的anti-MCRS1 抗体

  1. Human Polyclonal MCRS1 Primary Antibody for IF, IHC (p) - ABIN523843 : Xu, Zheng, Zhang, Zhao, Zhang, Wu, Wu, Wang, Wang, Zhang: MSP58 knockdown inhibits the proliferation of esophageal squamous cell carcinoma in vitro and in vivo. in Asian Pacific journal of cancer prevention : APJCP 2012 (PubMed)
    Show all 2 Pubmed References


Fruit Fly (Drosophila melanogaster) Microspherule Protein 1 (MCRS1) interaction partners

  1. Results suggest that dMCRS2 is required for loading of RNAP II complexes on the cyclin (显示 PCNA 抗体) gene promoters.

Human Microspherule Protein 1 (MCRS1) interaction partners

  1. Study shows that MCRS1 binds to cytoplasmic dynein (显示 DYNC1H1 抗体) and contributes to the establishment of centriolar satellites and ciliogenesis.

  2. MSP58 downregulation suppressed the proliferation and invasion of renal cell carcinoma (显示 MOK 抗体) cells.

  3. MCRS1 is phosphorylated by the Aurora-A kinase (显示 AURKA 抗体) in mitosis on Ser35/36.

  4. RINT-1 (显示 RINT1 抗体) interacts with MSP58 and UBF (显示 UBTF 抗体) within nucleoli and plays a role in ribosomal gene transcription.

  5. The immunoreactivity score (IRS (显示 IARS 抗体)) of MSP58 increased with tumor grade with grade IV gliomas exhibiting the highest expression and showed a highly significant positive correlation with the Ki-67 (显示 MKI67 抗体) index (r = 0.65, P < 0.001).

  6. Suggest that MSP58 plays an important role in tumorigenesis and progression and may help predict the prognosis of gastric cancer patients.

  7. MCRS1 overexpression induced non-small cell lung cancer proliferation through the miR (显示 MLXIP 抗体)-155-Rb1 (显示 RB1 抗体) pathway and DNA copy-number amplification is one of the mechanisms underlying MCRS1 overexpression in non-small cell lung cancer.

  8. MSP58 subnuclear localization is regulated by two nuclear import signals, and proper subcellular localization of MSP58 is critical for its role in transcriptional regulation. A molecular mechanism controls nuclear and nucleolar localization of MSP58.

  9. BAP1 (显示 RNF2 抗体) loss and MCRS1 down-regulation in renal cell carcinoma (显示 MOK 抗体) are associated with adverse clinicopathological features.

  10. MiR (显示 MLXIP 抗体)-129* down-regulation induced MCRS1 overexpression.

MCRS1 抗原简介


Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity.

Gene names and symbols associated with MCRS1

  • Reduction in Cnn dots 5 (Rcd5) 抗体
  • microspherule protein 1 L homeolog (mcrs1.L) 抗体
  • microspherule protein 1 (mcrs1) 抗体
  • microspherule protein 1 (MCRS1) 抗体
  • microspherule protein 1 (CpipJ_CPIJ004521) 抗体
  • microspherule protein 1 (Tsp_07041) 抗体
  • microspherule protein 1 (Tsp_07058) 抗体
  • microspherule protein 1 (Tsp_06917) 抗体
  • microspherule protein 1 (Mcrs1) 抗体
  • C78274 抗体
  • CG1135 抗体
  • dMCRS1 抗体
  • dMCRS2 抗体
  • Dmel\\CG1135 抗体
  • ICP22BP 抗体
  • INO80Q 抗体
  • l(3)r0166 抗体
  • l(3)rG166 抗体
  • MCRS1 抗体
  • mcrs2 抗体
  • MSP58 抗体
  • P78 抗体
  • wu:fj97a11 抗体
  • zgc:66428 抗体
  • zgc:77376 抗体

Protein level used designations for MCRS1

CG1135-PA , Rcd5-PA , lethal (3) rG166 , reduction in Cnn dots 5 , microspherule protein 1 , microspherule protein 1-like , 58 kDa microspherule protein , nucleolar protein , INO80 complex subunit J , INO80 complex subunit Q , cell cycle-regulated factor (78 kDa) , cell cycle-regulated factor p78

38478 Drosophila melanogaster
380567 Xenopus laevis
406557 Danio rerio
451881 Pan troglodytes
477616 Canis lupus familiaris
549534 Xenopus (Silurana) tropicalis
710919 Macaca mulatta
100022253 Monodelphis domestica
100051964 Equus caballus
100394625 Callithrix jacchus
100471618 Ailuropoda melanoleuca
100561650 Anolis carolinensis
100600396 Nomascus leucogenys
6036210 Culex quinquefasciatus
10903334 Trichinella spiralis
10903352 Trichinella spiralis
10912195 Trichinella spiralis
51812 Mus musculus
300222 Rattus norvegicus
10445 Homo sapiens
514410 Bos taurus
426664 Gallus gallus
100343297 Oryctolagus cuniculus
100724960 Cavia porcellus
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