anti-Hematopoietic Prostaglandin D Synthase (HPGDS) 抗体

Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. 再加上,我们可以发HPGDS 试剂盒 (13)HPGDS 蛋白 (11)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
HPGDS 27306 O60760
HPGDS 54486 Q9JHF7
HPGDS 58962 O35543
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Showing 10 out of 22 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 WB Western blot analysis of HPGDS expression in THP1 (A), Raw264.7 (B), PC12 (C) whole cell lysates. 200 μL Log in to see 13至14个工作日
非结合性 WB 50 μg Log in to see 7至9个工作日
非结合性 IHC (p), WB Anti-HPGDS / PGDS antibody IHC staining of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN958991 concentration 5 ug/ml. 50 μg Log in to see 7至9个工作日
大鼠 非结合性 IHC (p), WB Human Thymus (formalin-fixed, paraffin-embedded) stained with PGDS antibody ABIN337149 at 10 ug/ml followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7至9个工作日
非结合性 ICC, IHC, IP, WB DAB staining on IHC-P;;Samples: Human Stomach cancer Tissue 100 μg Log in to see 13至16个工作日
小鼠 非结合性 ICC, IHC, IP, WB Figure.DAB staining on IHC-P. Samples: Mouse Tissue 100 μg Log in to see 13至16个工作日
非结合性 IHC, IHC (p), WB Western Blot: HPGDS Antibody [NBP1-54625] - Titration: 0.2-1 ug/ml, Positive Control: Human Spleen. Immunohistochemistry-Paraffin: HPGDS Antibody [NBP1-54625] - Human Lung tissue, 5ug/ml. 100 μL Log in to see 8至11个工作日
非结合性 ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: HPGDS Antibody [NBP1-83322] Staining of human cell line A-431 shows positivity in nucleus but not nucleoli & cytoplasm. Immunohistochemistry-Paraffin: HPGDS Antibody [NBP1-83322] - Staining of human bone marrow shows moderate cytoplasmic positivity in megakaryocytes. 0.1 mL Log in to see 10至13个工作日
非结合性 IHC, WB   1 each Log in to see 7至9个工作日
非结合性 WB   100 μL Log in to see 7至9个工作日

通过反应活性、应用领域、克隆类型和共轭标记 HPGDS 抗体

特性 应用范围 宿主 克隆类型
Human , ,
Mouse (Murine)
Rat (Rattus)


Human Hematopoietic Prostaglandin D Synthase (HPGDS) interaction partners

  1. These observations suggest that tumor cell-derived inflammatory cytokines increase L-PGDS (显示 PTGDS 抗体) expression and subsequent PGD2 (显示 PTGDS 抗体) production in the tumor endothelial cells (ECs). This PGD2 (显示 PTGDS 抗体) acts as a negative regulator of the tumorigenic changes in tumor ECs.

  2. we have utilized a broad-scaled affinity proteomics approach to identify three proteins (CCL5 (显示 CCL5 抗体), HPGDS, and NPSR1 (显示 NPSR1 抗体)) with altered plasma levels in asthmatic children compared to healthy controls, representing the first evaluation of HPGDS and NPSR1 (显示 NPSR1 抗体) in plasma.

  3. the development of a competition binding assay amenable to high-throughput screening (HTS (显示 APCDD1 抗体)) in a scintillation proximity assay (SPA (显示 FASL 抗体)) format. This assay was used to screen an in-house compound library of approximately 280,000 compounds for novel H-PGDS inhibitors.

  4. Serum levels of beta trace protein and beta 2 microglobulin (显示 B2M 抗体) can be used to predict residual kidney function in hemodialysis patients.

  5. BTP and B2M (显示 B2M 抗体) levels are less affected than serum by amputation, and should be considered for future study of GFR (显示 RAPGEF5 抗体) estimation

  6. Hematopoietic prostaglandin D synthase defines a proeosinophilic pathogenic effector human T(H)2 cell subpopulation with enhanced function

  7. levels of L-PGDS (显示 PTGDS 抗体) in cervicovaginal secretions of pregnant women at different stages of parturition correlate with preterm birth.

  8. PTGDS (显示 PTGDS 抗体) mRNA expression was down-regulated in rapid-cycling bipolar disorder patients in a euthymic, depressive, and manic/hypomanic state compared with healthy control subjects.

  9. Expression of MR and prostaglandin D2 synthase (显示 PTGDS 抗体) is strongly correlated in adipose tissues from obese patients.

  10. These data indicate that scalp is spatially programmed via mast cell prostaglandin D-synthase (显示 PTGDS 抗体) distribution in a manner reminiscent of the pattern seen in androgenetic alopecia.

Mouse (Murine) Hematopoietic Prostaglandin D Synthase (HPGDS) interaction partners

  1. H-PGDS deficiency accelerates the production of SDF-1alpha and the activity of MMP-9 (显示 MMP9 抗体) in the antigen-stimulated intestine. SDF-1alpha receptor blockade or MMP-9 (显示 MMP9 抗体) inhibition relieves the exacerbated mast cell hyperplasia and manifestations observed in H-PGDS(-/-).

  2. HPGDS may play a role in the regulation of inflammation and epithelial cell health within the oviduct.

  3. Data suggest a role for hematopoietic prostaglandin D synthase-produced prostaglandin D(2) in the initial nuclear translocation of SOX9 (显示 SOX9 抗体).

  4. These data suggest that PGD(2) generated via HPGDS has detrimental effects after spinal cord injury and that blocking the activity of this enzyme can be beneficial.

  5. hPGD (显示 HPGD 抗体)(2)S-derived cyclopentenone prostaglandins may protect against inflammatory diseases, where T lymphocytes play a pathogenic role, as in rheumatoid arthritis, atopic eczema, and chronic rejection

  6. Our results demonstrated that the neuroprotective effects of HPGDS in our model are mediated by suppression of activation and infiltration of inflammatory cells.

HPGDS 抗原简介


The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep.

Gene names and symbols associated with HPGDS

  • hematopoietic prostaglandin D synthase (HPGDS) 抗体
  • prostaglandin D2 synthase (PTGDS) 抗体
  • hematopoietic prostaglandin D synthase (hpgds) 抗体
  • hematopoietic prostaglandin D synthase (Hpgds) 抗体
  • hematopoietic prostaglandin D synthase L homeolog (hpgds.L) 抗体
  • gsts 抗体
  • GSTS1-1 抗体
  • H-PGDS 抗体
  • hpgds 抗体
  • hpgds-a 抗体
  • hpgds-b 抗体
  • hpgdsa 抗体
  • L-PGDS 抗体
  • LPGDS 抗体
  • PDS 抗体
  • PGD2 抗体
  • pgds 抗体
  • PGDS2 抗体
  • Ptgds2 抗体
  • XlGSTS1 抗体

Protein level used designations for HPGDS

GST class-sigma , glutathione S-transferase sigma , glutathione-dependent PGD synthase , glutathione-dependent PGD synthetase , glutathione-requiring prostaglandin D synthase , hematopoietic prostaglandin D2 synthase , prostaglandin-H2 D-isomerase , PGD2 synthase , beta-trace protein , cerebrin-28 , glutathione-independent PGD synthase , glutathione-independent PGD synthetase , lipocalin-type prostaglandin D synthase , lipocalin-type prostaglandin-D synthase , prostaglandin D synthase , prostaglandin-D2 synthase , prostaglandin D2 synthase, hematopoietic , glutathione S-transferase , prostaglandin D2 synthase 2, hematopoietic , H-PGDS , prostaglandin-D synthase , hematopoietic prostaglandin D synthase , hematopoietic prostaglandin D synthase a , prostaglandin D2 synthase, hematopoietic a

27306 Homo sapiens
5730 Homo sapiens
448666 Xenopus (Silurana) tropicalis
54486 Mus musculus
58962 Rattus norvegicus
395863 Gallus gallus
100139892 Bos taurus
398969 Xenopus laevis
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