anti-Glucosaminyl (N-Acetyl) Transferase 1, Core 2 (GCNT1) 抗体

GCNT1 is a member of the beta-1,6-N-acetylglucosaminyltransferase gene family. 再加上,我们可以发GCNT1 试剂盒 (13)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
GCNT1 2650 Q02742
GCNT1 14537 Q09324
GCNT1 64043  
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antibodies-online.cn销售最多的anti-GCNT1 抗体

Showing 10 out of 71 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 IHC (p), WB The anti-GCNT1 Pab (ABIN389033) is used in Western blot to detect GCNT1 in mouse kidney tissue lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10至11个工作日
$335.50
详细
非结合性 IHC (p), WB Western blot analysis of anti-GCNT1 Antibody (C-term) (ABIN389034) in CEM cell line lysates (35 µg/lane). GCNT1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10至11个工作日
$335.50
详细
非结合性 EIA, IHC (p), WB 0.4 mL Log in to see 6至8个工作日
$390.50
详细
非结合性 EIA, IHC (p), WB 0.4 mL Log in to see 6至8个工作日
$390.50
详细
非结合性 WB GCNT1 Antibody (Center)  western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the GCNT1 antibody detected the GCNT1 protein (arrow). 400 μL Log in to see 10至11个工作日
$335.50
详细
非结合性 WB Western blot analysis in T47D cell line lysates (35ug/lane). 400 μL Log in to see 2至3个工作日
$515.63
详细
非结合性 IHC (p), WB Antibody is used in Western blot to detect GCNT1 in mouse kidney tissue lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. BC = breast carcinoma; HC = hepatocarcinoma. 400 μL Log in to see 2至3个工作日
$515.63
详细
非结合性 IHC (p) Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human duodenum with GCNT1 polyclonal antibody  shows strong cytoplasmic positivity in glandular cells. 100 μL Log in to see 11至12个工作日
$517.50
详细
小鼠 非结合性 WB Western Blot analysis of GCNT1 expression in transfected 293T cell line by GCNT1 MaxPab polyclonal antibody.<br><br>Lane1:GCNT1 transfected lysate(47.08 KDa).<br>Lane2:Non-transfected lysate.<br> 50 μg Log in to see 11至12个工作日
$440.00
详细
非结合性 IHC, IHC (p) Immunohistochemistry: Glucosaminyl (N-acetyl) Transferase 1/GCNT1 Antibody [NBP1-86809] - Staining of human small intestine shows cytoplasmic and membranous positivity in glandular cells. Immunohistochemistry-Paraffin: Glucosaminyl (N-acetyl) Transferase 1/GCNT1 Antibody [NBP1-86809] - Staining of human duodenum shows strong cytoplasmic positivity in glandular cells. 0.1 mL Log in to see 10至13个工作日
$491.63
详细

引用最多的anti-GCNT1 抗体

  1. Human Polyclonal GCNT1 Primary Antibody for WB - ABIN515997 : Petrosyan, Cheng: Golgi fragmentation induced by heat shock or inhibition of heat shock proteins is mediated by non-muscle myosin IIA via its interaction with glycosyltransferases. in Cell stress & chaperones 2014 (PubMed)

更多抗GCNT1的相互作用对抗体

Human Glucosaminyl (N-Acetyl) Transferase 1, Core 2 (GCNT1) interaction partners

  1. GCNT1 expression in prostate biopsy specimen is a significant and independent predictor of recurrence after radical prostatectomy, which can be used in pre-treatment decision making for the patient.

  2. GCNT1 expression in prostate cancer positively correlates with cancer progression and prostate-specific antigen recurrence.

  3. Results show that ST3Gal1 (显示 ST3GAL1 抗体) uses GM130 (显示 GOLGA2 抗体)-GRASP65 (显示 GORASP1 抗体) and giantin (显示 GOLGB1 抗体), whereas C2GnT-L uses only giantin (显示 GOLGB1 抗体) for Golgi targeting and defective giantin (显示 GOLGB1 抗体) dimerization in PC-3 (显示 PCSK1 抗体) and DU145 prostate cancer cells causes fragmentation of the Golgi and prevents its targeting.

  4. NMIIA is the master regulator of Golgi fragmentation induced by heat shock or inhibition/depletion of HSP70 (显示 HSP70 抗体)/90 through interaction with gylosyltransferases.

  5. GCNT1 is over-expressed in prostate cancer and is associated with higher levels of core 2 O-sLe(x) in PSA (显示 PLAG1 抗体), PAP (显示 REG3A 抗体) and MUC1 (显示 MUC1 抗体) proteins.

  6. Immunohistochemical expression of core 2 beta1,6-N-acetylglucosaminyl transferase 1 (C2GnT1) in endometrioid-type endometrial carcinoma may be a novel potential prognostic factor.

  7. C2GnT-expressing prostate cancer cells evade NK cell immunity and survive longer in the host blood circulation, thereby resulting in the promotion of prostate cancer metastasis.

  8. GOLPH3 (显示 GOLPH3 抗体) can regulate cell-cell interaction by controlling Golgi retention of C2GnT1.

  9. Down-regulation of C2GnT1 is correlated with breast cancer

  10. The X-ray crystal structure (2.3 A resolution) of a mutant form of C2GnT-L (C217S) in complex with UDP was solved. C2GnT-L exists in an "open" conformation and a "closed" conformation.

Mouse (Murine) Glucosaminyl (N-Acetyl) Transferase 1, Core 2 (GCNT1) interaction partners

  1. we show that Gcnt1 transcription and subsequent P-lselectin ligand induction in Th1 cells is governed by binding of STAT4 and T-bet to a distal enhancer and further regulated by epigenetic marks such as H3K27me3.

  2. simultaneous deletion of the Core2 beta1,6-N-acetylglucosaminyltransferase (C2GnT) enzymes C2GnT1 and C2Gnt2 (显示 GCNT3 抗体) resulted in delayed expulsion of worms.

  3. striking differences between the requirement of FucT-VII (显示 FUT7 抗体) and C2GlcNAcT-I for Ligands for E-selectin (显示 SELE 抗体) and P-selectin (显示 SELP 抗体) expression in CD4 (显示 CD4 抗体)+ T cells.

  4. Core2 O-glycan structure is essential for expression of SI and DDP (显示 TIMM8A 抗体)-IV during intestinal cell differentiation.

  5. Distinct functions for C2GlcNAcT-I in the differential elaboration of endothelial venule glycoproteins that set a threshold for the amount of L-selectin (显示 SELL 抗体) needed for lymphocyte homing.

  6. data demonstrate that multiple C2GlcNAcT enzymes can contribute to P-selectin (显示 SELP 抗体) ligand formation and may cooperate with C2GlcNAcT-I in the control of CD8 (显示 CD8A 抗体) T cell trafficking

  7. IGnT deficient mice had reduced spontaneous locomotive activity, and the number of peripheral blood lymphocytes was also reduced and renal function decreased in the deficient mice

  8. Data report the x-ray crystal structures of murine core 2 O-glycan (Galbeta1-3[GlcNAcbeta1-6]GalNAc-O-Ser (显示 SIGLEC1 抗体)/Thr (显示 TRH 抗体)) (C2GnT-L) in the absence and presence of the acceptor substrate Galbeta1-3GalNAc at 2.0 and 2.7A resolution, respectively.

  9. These results suggest that the core 2 GlcNAc extended glycan chains on megalin (显示 LRP2 抗体) can change the ligand-binding affinity and capacity.

  10. Pancreas carcinoma antigen, C2GnT, fused to invariant chain elicits T-cell response and tumor growth inhibition.

GCNT1 抗原简介

蛋白简介

This gene is a member of the beta-1,6-N-acetylglucosaminyltransferase gene family. It is essential to the formation of Gal beta 1-3(GlcNAc beta 1-6)GalNAc structures and the core 2 O-glycan branch. The gene coding this enzyme was originally mapped to 9q21, but was later localized to 9q13. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene names and symbols associated with GCNT1

  • glucosaminyl (N-acetyl) transferase 1, core 2 L homeolog (gcnt1.L) 抗体
  • glucosaminyl (N-acetyl) transferase 1, core 2 (GCNT1) 抗体
  • glucosaminyl (N-acetyl) transferase 1, core 2 (Gcnt1) 抗体
  • 5630400D21Rik 抗体
  • B130048E03 抗体
  • C2 GlcNAcT 抗体
  • C2GNT 抗体
  • C2GNT-L 抗体
  • C2GNT1 抗体
  • core 2 GlcNAc-T 抗体
  • G6NT 抗体
  • IGnT 抗体
  • NACGT2 抗体
  • NAGCT2 抗体

Protein level used designations for GCNT1

enzymatic glycosylation-regulating , glucosaminyl (N-acetyl) transferase 1, core 2 (beta-1,6-N-acetylglucosaminyltransferase) , Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase , glucosaminyl (N-acetyl) transferase 1, core 2 , glucosaminyl transferase 1, core 2 , beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase-like , beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N--acetylglucosaminyltransferase , beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase , beta-1,6-N-acetylglucosaminyltransferase , core 2 GnT , core 2 beta-1,6-N-acetylglucosaminyltransferase I , core 2 beta1,6 N-acetylglucosaminyltransferase-I , core 2 branching enzyme , core 2-branching enzyme , core2-GlcNAc-transferase , beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase (Core 2 branching enzyme) (Core2-GlcNAc-transferase) (C2GNT) , C2GNT , core 2 GNT , beta1,6 N-acetylglucosaminyltransferase

GENE ID SPECIES
380501 Xenopus laevis
427260 Gallus gallus
704639 Macaca mulatta
100011966 Monodelphis domestica
100347030 Oryctolagus cuniculus
100397450 Callithrix jacchus
100453351 Pongo abelii
100481771 Ailuropoda melanoleuca
100590764 Nomascus leucogenys
2650 Homo sapiens
14537 Mus musculus
281778 Bos taurus
484158 Canis lupus familiaris
64043 Rattus norvegicus
101121316 Ovis aries
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