anti-GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1) 抗体

G3BP1 encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. 再加上,我们可以发GTPase Activating Protein (SH3 Domain) Binding Protein 1 蛋白 (12)GTPase Activating Protein (SH3 Domain) Binding Protein 1 试剂盒 (9)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
G3BP1 10146 Q13283
G3BP1 171092  
G3BP1 27041 P97855
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Showing 10 out of 151 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 IHC, IP, WB WB Suggested Anti-G3BP1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  HT1080 cell lysate G3BP1 is strongly supported by BioGPS gene expression data to be expressed in Human HT1080 cells <b>IP Suggested Anti-G3BP1 Antibody </b><br><b>Positive Control: </b>NT2 CELL/BRAIN TISSUE 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 WB Host:  Rabbit  Target Name:  G3BP  Sample Type:  HepG2  Lane A:  Primary Antibody  Lane B:  Primary Antibody + Blocking Peptide  Primary Antibody Concentration:  2.5ug/mL  Peptide Concentration:  2.0ug/mL  Lysate Quantity:  25ug/lane  Gel Concentration:  12% WB Suggested Anti-G3BP Antibody Titration:  2.5ug/ml  ELISA Titer:  1:312500  Positive Control:  HepG2 cell lysate 100 μL Log in to see 2至3个工作日
$229.00
详细
小鼠 非结合性 IF, IHC, WB Immunofluorescence of monoclonal antibody to G3BP on HeLa cell (antibody concentration 10 µg/mL). Western blot analysis of G3BP over-expressed 293 cell line, cotransfected with G3BP Validated Chimera RNAi used as specificity and loading control. 100 μg Log in to see 8至11个工作日
$461.00
详细
非结合性 ICC, IF, IHC, IHC (p), WB Western Blot: G3BP1 Antibody [NBP1-83404] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells).Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells) Immunocytochemistry/Immunofluorescence: G3BP1 Antibody [NBP1-83404] - Staining of human cell line U-251MG shows positivity in cytoplasm. 0.1 mL Log in to see 10至13个工作日
$491.63
详细
非结合性 IHC (p), WB G3BP1 Antibody (C-term) (ABIN657707) western blot analysis in Jurkat cell line lysates (35 µg/lane). This demonstrates the G3BP1 antibody detected the G3BP1 protein (arrow). 400 μL Log in to see 10至11个工作日
$335.50
详细
非结合性 IC, IF, IHC, WB Immunofluorescent analysis of G3BP1 staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of G3BP1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13至14个工作日
$487.50
详细
非结合性 IC, IF, IHC, WB Immunofluorescent analysis of G3BP1 (pS232) staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of G3BP1 (pS232) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13至14个工作日
$575.00
详细
非结合性 WB 100 μg Log in to see 2至3个工作日
$275.00
详细
Cow 非结合性 WB Host:  Rabbit  Target Name:  G3BP1  Sample Type:  Pancreas tumor lysates  Antibody Dilution:  1.0ug/ml 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 IHC, ELISA, WB Western blot analysis of extracts from HeLa cells, using G3BP-1 (Phospho-Ser232) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using G3BP-1 (Phospho-Ser232) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
$302.50
详细

引用最多的anti-GTPase Activating Protein (SH3 Domain) Binding Protein 1 抗体

  1. Human Monoclonal G3BP1 Primary Antibody for IF, IHC (p) - ABIN564390 : Norazit, Meedeniya, Nguyen, Mackay-Sim: Progressive loss of dopaminergic neurons induced by unilateral rotenone infusion into the medial forebrain bundle. in Brain research 2010 (PubMed)
    Show all 4 Pubmed References

  2. Human G3BP1 Primary Antibody for IHC - ABIN966168 : Tao, Wollscheid, OBrien, Eng, Li, Bodenmiller, Watts, Hood, Aebersold: Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry. in Nature methods 2005 (PubMed)
    Show all 5 Pubmed References

  3. Cow (Bovine) Polyclonal G3BP1 Primary Antibody for WB - ABIN2780221 : Kociok, Esser, Unfried, Parker, Schraermeyer, Grisanti, Toqué, Heimann: Upregulation of the RAS-GTPase activating protein (GAP)-binding protein (G3BP) in proliferating RPE cells. in Journal of cellular biochemistry 1999 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal G3BP1 Primary Antibody for IP, PLA - ABIN438758 : Fujimura, Sasaki, Anderson: Selenite targets eIF4E-binding protein-1 to inhibit translation initiation and induce the assembly of non-canonical stress granules. in Nucleic acids research 2012 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal G3BP1 Primary Antibody for IF (p), IHC (p) - ABIN801153 : Luo, Fang, Jin, Wang, An, Xu, Chen, Xiao: Label-free quantitative phosphoproteomic analysis reveals differentially regulated proteins and pathway in PRRSV-infected pulmonary alveolar macrophages. in Journal of proteome research 2014 (PubMed)

  6. Human Polyclonal G3BP1 Primary Antibody for IHC - ABIN966169 : Beausoleil, Jedrychowski, Schwartz, Elias, Villén, Li, Cohn, Cantley, Gygi: Large-scale characterization of HeLa cell nuclear phosphoproteins. in Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)
    Show all 3 Pubmed References

  7. Human Polyclonal G3BP1 Primary Antibody for IF, WB - ABIN523522 : Kaehler, Isensee, Nonhoff, Terrey, Hucho, Lehrach, Krobitsch: Ataxin-2-like is a regulator of stress granules and processing bodies. in PLoS ONE 2012 (PubMed)

  8. Human Polyclonal G3BP1 Primary Antibody for ICC, IF - ABIN4313041 : Martin, Bellora, González-Vallinas, Irimia, Chebli, de Toledo, Raabe, Eyras, Urlaub, Blencowe, Tazi: Preferential binding of a stable G3BP ribonucleoprotein complex to intron-retaining transcripts in mouse brain and modulation of their expression in the cerebellum. in Journal of neurochemistry 2016 (PubMed)

更多抗GTPase Activating Protein (SH3 Domain) Binding Protein 1的相互作用对抗体

Human GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1) interaction partners

  1. Activated glucocorticoid receptor (显示 NR3C1 抗体) induced phosphorylation of v-AKT (显示 AKT1 抗体) Murine Thymoma Viral Oncogene (显示 RAB1A 抗体) Homologue (AKT (显示 AKT1 抗体)) kinase, which in turn phosphorylated and promoted nuclear translocation of G3BP1. The nuclear G3BP1 bound to the G3BP1 consensus sequence located on primary miR (显示 MLXIP 抗体)-15b~16-2 and miR (显示 MLXIP 抗体)-23a~27a~24-2 to inhibit their maturation.

  2. Results show the crystal structure of the NTF2 (显示 NUTF2 抗体)-like domain of G3BP-1 in complex with nsP3 (显示 SH2D3C 抗体) protein revealing a poly-complex of G3BP-1 dimers interconnected through the FGDF motifs in nsP3 (显示 SH2D3C 抗体). Although in vitro and in vivo binding studies revealed a hierarchical interaction of the two FGDF motifs with G3BP-1, viral growth curves clearly demonstrated that two intact FGDF motifs are required for efficient viral replication.

  3. Based on insights from the structures and existing biochemical data, the existence of an evolutionarily conserved ribonucleoprotein (RNP (显示 RNPC3 抗体)) complex consisting of Caprin-1, FMRP (显示 FMR1 抗体) and G3BP1 is proposed.

  4. G3BP1 interacts directly with the foot-and-mouth disease virus internal ribosome entry site and negatively regulates translation.

  5. The data suggested that JNK (显示 MAPK8 抗体)-enhanced Tudor-SN phosphorylation promotes the interaction between Tudor-SN and G3BP and facilitates the efficient recruitment of Tudor-SN into stress granules under conditions of sodium arsenite-induced oxidative stress.

  6. These data support a role for casein kinase 2 in regulation of protein synthesis by downregulating stress granule formation through G3BP1.

  7. G3BP1 is differentially methylated on specific arginine residues by protein arginine methyltransferase (显示 PRMT1 抗体) (PRMT) 1 (显示 PRMT1 抗体) and PRMT5 (显示 PRMT5 抗体) in its RGG domain.

  8. Our data define G3BP1 as a novel independent prognostic factor that is correlated with gastric cancer progression.

  9. G3BP mediates the condensation of stress granules by shifting between two different states that are controlled by the phosphorylation of S149 and by binding to Caprin1 or USP10 (显示 USP10 抗体).

  10. Host G3BP1 captures HIV-1 RNA transcripts and thereby restricts mRNA translation, viral protein production and virus particle formation.

Mouse (Murine) GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1) interaction partners

  1. the aberrant mutant SOD1 (显示 SOD1 抗体)-G3BP1 interaction affects stress granule dynamics

  2. G3BP is involved in a new functional mechanism to regulate non-coding RNAs including intron-retaining transcripts, and thus have broad implications for neuronal gene regulation, where intron retention is widespread

  3. G3bp1 posttranscriptionally regulates miRNA-1 processing in the heart.

  4. Our findings identified a novel function of G3BP1 in the progression of breast cancer via activation of the epithelial-to-mesenchymal transition

  5. Cytoplasmic granule containing HERMES (显示 CD44 抗体), NonO (显示 NONO 抗体), PSF (显示 IL-3 抗体), and G3BP1 is a neuronal RNA-protein granule that is transported in neurites during retinal differentiation.

  6. These results show, for the first time, a requirement for G3BP1 in the control of neuronal plasticity and calcium homeostasis

  7. Data show that protein kinase (显示 CDK7 抗体) R as the principal kinase that mediates eukaryotic initiation factor 2alpha (eIF2alpha (显示 EIF2S1 抗体)) phosphorylation by large RasGAP (显示 RASA1 抗体) SH3-binding protein (显示 SH3BP5 抗体) (G3BP)-induced granules.

  8. arguments against G3BP1 being a genuine RasGAP (显示 RASA1 抗体)-binding partner

  9. G3BP1 is a novel Ctnnb1 (显示 CTNNB1 抗体) mRNA binding protein. Methylation of G3BP1 constitutes a molecular switch that regulates Ctnnb1 (显示 CTNNB1 抗体) mRNA in response to Wnt3a (显示 WNT3A 抗体).

  10. IMP-1 (显示 IMPA1 抗体) associates with HuD (显示 ELAVL4 抗体) and G3BP-1 proteins in an RNA-dependent manner and binds directly to tau mRNA. We also show an RNA-dependent association between G3BP-1 and HuD (显示 ELAVL4 抗体) proteins

Pig (Porcine) GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1) interaction partners

  1. It has been demonstrated a depletion of G3BP1 and TIA-1/TIAR in senescent cells and it was shown that the loss of G3BP1 contributed to impaired stress granules formation.

GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1) 抗原简介

蛋白简介

This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Gene names and symbols associated with G3BP1

  • G3BP stress granule assembly factor 1 (G3BP1) 抗体
  • GTPase activating protein (SH3 domain) binding protein 1 (g3bp1) 抗体
  • GTPase activating protein (SH3 domain) binding protein 1 L homeolog (g3bp1.L) 抗体
  • Ras-GTPase-activating protein SH3-domain-binding protein (LOC100304885) 抗体
  • G3BP stress granule assembly factor 1 (G3bp1) 抗体
  • GTPase activating protein (SH3 domain) binding protein 1 (G3bp1) 抗体
  • AI849976 抗体
  • B430204O07 抗体
  • C87777 抗体
  • fj17h05 抗体
  • G3bp 抗体
  • G3BP1 抗体
  • HDH-VIII 抗体
  • MGC53271 抗体
  • mKIAA4115 抗体
  • RGD1310666 抗体
  • wu:fj17h05 抗体
  • zgc:56034 抗体

Protein level used designations for G3BP1

ATP-dependent DNA helicase VIII , G3BP-1 , GAP SH3 domain-binding protein 1 , GAP binding protein , Ras-GTPase-activating protein SH3-domain-binding protein , RasGAP-associated endoribonuclease G3BP , ras GTPase-activating protein-binding protein 1 , GTPase activating protein (SH3 domain) binding protein 1 , ATP-dependent DNA/RNA helicase G3BP , Ras-GTPase-activating protein SH3-domain binding protein 1 , GAP SH3 binding protein , HDH-VIII

GENE ID SPECIES
10146 Homo sapiens
335512 Danio rerio
380390 Xenopus laevis
471711 Pan troglodytes
534214 Bos taurus
713884 Macaca mulatta
100304885 Ictalurus punctatus
171092 Rattus norvegicus
27041 Mus musculus
479322 Canis lupus familiaris
100513766 Sus scrofa
100172476 Pongo abelii
100725714 Cavia porcellus
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