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FBXO21 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. 再加上，我们可以发F-Box Protein 21 试剂盒 (12) 和 F-Box Protein 21 蛋白 (3)和数多这个蛋白质的别的产品。
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Ser291-phosphorylated form of the multifunctional protein and stem cell marker, CD44 (显示 CD44 抗体), inhibits FBXO21-directed degradation of P-gp (显示 ABCB4 抗体).
SCF (显示 KITLG 抗体)(FBXO21) polyubiquitylates EID1 (显示 EID1 抗体) both in vitro and in vivo and is required for the efficient degradation of EID1 (显示 EID1 抗体) in both cycling and quiescent cells.
The results suggest that EID1 (显示 EID1 抗体) is a bona fide substrate of FBXO21 and that the control of EID1 (显示 EID1 抗体) abundance by SCF (显示 KITLG 抗体)(FBXO)(21) might affect the transcriptional repression activity of EID1 (显示 EID1 抗体).
Lysine 29-linkage of ASK1 by Skp1-Cullin 1-Fbxo21 ubiquitin ligase complex is required for antiviral innate response.
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants.
F-box only protein 21
, F-box protein 21
, LOW QUALITY PROTEIN: F-box only protein 21