This gene is a member of the ras superfamily, and is expressed in normal ovarian and breast epithelial cells, but not in ovarian and breast cancers. It is an imprinted gene, with monoallelic expression of the paternal allele, which is associated with growth suppression. Thus, this gene appears to be a putative tumor suppressor gene whose function is abrogated in ovarian and breast cancers. [provided by RefSeq, Oct 2010].
Li, Ramani, Sun, Zee, Grant, Yang, Xia, Oh, Ko, Mato, Lu: "Forced expression of methionine adenosyltransferase 1A in human hepatoma cells suppresses in vivo tumorigenicity in mice." in: The American journal of pathology, Vol. 176, Issue 5, pp. 2456-66, (2010) (PubMed).
Aliases for DIRAS3 抗体
DIRAS family GTPase 3 (DIRAS3) 抗体 DIRAS family GTP binding RAS like 3 (diras3) 抗体 arhi 抗体 ARHI 抗体 DIRAS3 抗体 noey2 抗体 NOEY2 抗体