anti-Chloride Channel Kb (CLCNKB) 抗体

The protein encoded by CLCNKB is a member of the family of voltage-gated chloride channels. 再加上,我们可以发CLCNKB 蛋白 (4)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
CLCNKB 56365 Q9WUB6
CLCNKB 79430 P51802
CLCNKB 1188 P51801
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antibodies-online.cn销售最多的anti-CLCNKB 抗体

Showing 10 out of 55 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-CLCNKB Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Jurkat cell lysate 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 WB WB Suggested Anti-CLCNKB Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Human kidney 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 EIA, WB CLCNKB Antibody (N-term) western blot analysis in mouse kidney tissue lysates (35µg/lane).This demonstrates the CLCNKB antibody detected the CLCNKB protein (arrow). 0.4 mL Log in to see 6至8个工作日
$390.50
详细
Cow 非结合性 WB 50 μg Log in to see 11至14个工作日
$551.83
详细
非结合性 WB 50 μg Log in to see 11至14个工作日
$551.83
详细
非结合性 ELISA, WB Western blot analysis of CLCNKB using COLO205 whole cell lysates 100 μL Log in to see 11至12个工作日
$390.77
详细
小鼠 非结合性 WB CLCNKB Antibody (N-term)  western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the CLCNKB antibody detected the CLCNKB protein (arrow). 400 μL Log in to see 10至11个工作日
$335.50
详细
非结合性 WB CLCNKB antibody used at 0.25 ug/ml to detect target protein. 50 μg Log in to see 9至11个工作日
$473.93
详细
非结合性 WB CLCNKB antibody used at 0.5 ug/ml to detect target protein. 50 μg Log in to see 9至11个工作日
$473.93
详细
非结合性 IHC, ELISA, WB 50 μg Log in to see 2至3个工作日
$446.88
详细

更多抗CLCNKB的相互作用对抗体

Mouse (Murine) Chloride Channel Kb (CLCNKB) interaction partners

  1. Loss of ClC-K2 compromises TAL (显示 TALDO1 抗体) function and abolishes salt reabsorption in the distal convoluted tubule. Our data suggest that ClC-K2 is crucial for renal salt reabsorption and concentrating ability. ClC-K2-deficient mice in most aspects mimic patients with Bartter's syndrome type 3.

  2. Through the combined effects of pHi and pHo on ClC-K2, might be a key regulator of NaCl absorption.

  3. IGF-1 (显示 IGF1 抗体), by stimulating ClC-K2 channels, promotes net Na(+) and Cl(-) reabsorption, thus reducing driving force for potassium secretion by the cortical collecting duct.

Human Chloride Channel Kb (CLCNKB) interaction partners

  1. Taking advantage of the largest number of functional results of CLCNKB mutations, we reveal the functionally important domains and severe mutational spots of the hClC-Kb channel and establish the genotype-phenotype association in classic Bartter's Syndrome.

  2. Five patients had 1 (显示 SLC35A2 抗体) or more mutations in CLCNKB, of whom 3 had homozygous mutations and 2 had single heterozygous mutations and only in CLCNKB had hypocalciuria.

  3. Single loci of tag Single Nucleotide Polymorphisms of CLCNKA_B are not enough to increase the Essential Hypertension susceptibility, the combination of CLCNKA (显示 CLCNKA 抗体) SNP, salt, marine products, meat, edible oil consumption is associated with elevated risk

  4. results demonstrate that the carboxyl terminus of hClC-Kb is not part of the binding site for barttin (显示 BSND 抗体), but functionally modifies the interplay with barttin (显示 BSND 抗体).

  5. These results demonstrate that mutations in a cluster of hydrophobic residues within transmembrane domain 1 affect barttin (显示 BSND 抗体)-CLC-K interaction and impair gating modification by the accessory subunit

  6. we report here for the first time that ClC-Kb disease-causing mutations located around the selectivity filter can result in both reduced surface expression and hyperactivity in heterologous expression systems

  7. Case Report: 2 mutations in the CLCNKB gene, leading to a molecular diagnosis of Bartter syndrome type III in case of sudden infant death.

  8. R8W and G47R, two naturally occurring barttin (显示 BSND 抗体) mutations identified in patients with Bartter syndrome type IV, reduce barttin (显示 BSND 抗体) palmitoylation and CLC-K/barttin (显示 BSND 抗体) channel activity.

  9. HEK293 cells the potentiating effect of niflumic acid (NFA) on CLC-Ka/barttin (显示 BSND 抗体) and CLC-Kb/barttin (显示 BSND 抗体) channels seems to be absent while the blocking efficacy of niflumic acid and benzofuran derivatives observed in oocytes is preserved

  10. study investigated the functional consequences of seven mutations; four mutants carried no current whereas others displayed a 30-60 percent reduction in conductance as compared with wild-type ClC-Kb

Xenopus laevis Chloride Channel Kb (CLCNKB) interaction partners

  1. The open probability and mean open time of ClC-2 (显示 CLCN2 抗体) was voltage dependent, decreasing dramatically as the patches were depolarized. ClC-2 (显示 CLCN2 抗体) is uniquely suitable to promote anion secretion with little anion reabsorption.

CLCNKB 抗原简介

蛋白简介

The protein encoded by this gene is a member of the family of voltage-gated chloride channels. Chloride channels have several functions, including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. This gene is expressed predominantly in the kidney and may be important for renal salt reabsorption. Mutations in this gene are associated with autosomal recessive Bartter syndrome type 3 (BS3). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CLCNKB

  • chloride voltage-gated channel Kb (CLCNKB) 抗体
  • chloride channel Kb (CLCNKB) 抗体
  • chloride channel, voltage-sensitive Kb (Clcnkb) 抗体
  • chloride voltage-gated channel Kb (Clcnkb) 抗体
  • chloride channel, voltage-sensitive Kb L homeolog (clcnkb.L) 抗体
  • chloride channel K (clcnk) 抗体
  • chloride channel protein ClC-Ka (LOC100017912) 抗体
  • chloride channel protein ClC-Kb (LOC100400180) 抗体
  • chloride channel protein ClC-Kb (LOC100590605) 抗体
  • chloride channel protein ClC-Kb (LOC100730738) 抗体
  • ClC-k 抗体
  • ClC-K2 抗体
  • ClC-K2L 抗体
  • Clc-Ka 抗体
  • clc-kb 抗体
  • Clck2 抗体
  • clckb 抗体
  • Clcnk1l 抗体
  • CLCNKA 抗体
  • clcnka-A 抗体
  • Clcnkb 抗体
  • clk-k2 抗体
  • DKFZp469N0132 抗体
  • x6clck 抗体
  • xCIC-K 抗体
  • xClC-K 抗体
  • zgc:64141 抗体

Protein level used designations for CLCNKB

chloride channel Kb , chloride channel Ka , chloride channel K1-like; putative basolateral cTAL chloride channel ClC-Ka , chloride channel protein ClC-Kb , clC-K2 , putative basolateral mTAL chloride channel ClC-Ka , chloride channel K2 , chloride channel, kidney, B , CIC-K , chloride channel protein ClC-Kb-like , chloride channel, voltage-sensitive Kb

GENE ID SPECIES
703476 Macaca mulatta
428190 Gallus gallus
456470 Pan troglodytes
100171573 Pongo abelii
56365 Mus musculus
79430 Rattus norvegicus
1188 Homo sapiens
378616 Xenopus laevis
393353 Danio rerio
100017912 Monodelphis domestica
100400180 Callithrix jacchus
100590605 Nomascus leucogenys
100730738 Cavia porcellus
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