anti-Chloride Channel 2 (CLCN2) 抗体

CLCN2 encodes a voltage-gated chloride channel. 再加上,我们可以发Chloride Channel 2 蛋白 (6)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
CLCN2 12724 Q9R0A1
CLCN2 1181 P51788
CLCN2 29232 P35525
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antibodies-online.cn销售最多的anti-Chloride Channel 2 抗体

Showing 10 out of 68 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
山羊 非结合性 ELISA, WB   100 μg Log in to see 6至7个工作日
$429.62
详细
非结合性 EIA, WB CLCN2 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35µg/lane).This demonstrates the CLCN2 antibody detected the CLCN2 protein (arrow). CLCN2 Antibody (N-term) western blot analysis in mouse Neuro-2a cell line lysates (35µg/lane).This demonstrates the CLCN2 antibody detected the CLCN2 protein (arrow). 0.4 mL Log in to see 6至8个工作日
$390.50
详细
小鼠 非结合性 WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (64.24 KDa) . Dilution: 1:500~1000 100 μg Log in to see 8至11个工作日
$461.00
详细
山羊 非结合性 IHC, IHC (p) Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-CLCN2 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml. 50 μg Log in to see 11至14个工作日
$484.00
详细
小鼠 非结合性 RNAi, ELISA, WB CLCN2 monoclonal antibody (M01), clone 3E1 Western Blot analysis of CLCN2 expression in Hela S3 NE . Western blot analysis of CLCN2 over-expressed 293 cell line, cotransfected with CLCN2 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with CLCN2 monoclonal antibody (M01), clone 3E1. GAPDH ( 36.1 kDa ) used as specificity and loading control. 100 μg Log in to see 11至12个工作日
$440.00
详细
Bat 山羊 非结合性 ELISA, WB 100 μg Log in to see 7至9个工作日
$610.50
详细
非结合性 WB CLCN2 Antibody (N-term)  western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the CLCN2 antibody detected the CLCN2 protein (arrow). CLCN2 Antibody (N-term)  western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the CLCN2 antibody detected the CLCN2 protein (arrow). 400 μL Log in to see 10至11个工作日
$335.50
详细
非结合性 ELISA, WB Western blot analysis of CLCN2 using K562 whole cell lysates 100 μL Log in to see 11至12个工作日
$390.77
详细
Cow 山羊 非结合性 EIA, WB   0.1 mg Log in to see 8至11个工作日
$462.00
详细
山羊 非结合性 ELISA, WB Western Blot: CLCN2 Antibody [NBP1-52032] - Analysis of CLCN2 in HeLa lysate (35ug protein in RIPA buffer) using this antibody at 0.3 ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7至9个工作日
$485.88
详细

引用最多的anti-Chloride Channel 2 抗体

  1. Human Monoclonal CLCN2 Primary Antibody for RNAi, ELISA - ABIN560397 : Alessi, Andjelkovic, Caudwell, Cron, Morrice, Cohen, Hemmings: Mechanism of activation of protein kinase B by insulin and IGF-1. in The EMBO journal 1997 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal CLCN2 Primary Antibody for WB - ABIN394461 : Ferrer, Corneo, Davis, Wan, Miyagishima, King, Maminishkis, Marugan, Sharma, Shure, Temple, Miller, Bharti: A multiplex high-throughput gene expression assay to simultaneously detect disease and functional markers in induced pluripotent stem cell-derived retinal pigment epithelium. in Stem cells translational medicine 2014 (PubMed)

  3. Human Polyclonal CLCN2 Primary Antibody for ELISA, WB - ABIN4299049 : Cornejo, Niemeyer, Zúñiga, Yusef, Sepúlveda, Cid: Rapid recycling of ClC-2 chloride channels between plasma membrane and endosomes: role of a tyrosine endocytosis motif in surface retrieval. in Journal of cellular physiology 2009 (PubMed)

更多抗Chloride Channel 2的相互作用对抗体

Zebrafish Chloride Channel 2 (CLCN2) interaction partners

  1. Identification and characterization of the zebrafish ClC (显示 CLCF1 抗体)-2a/b/c chloride channel (显示 CLCA1 抗体) orthologs.

Mouse (Murine) Chloride Channel 2 (CLCN2) interaction partners

  1. High fat diet -treated mice lacking ClC-2 showed inhibited hepatic lipid accumulation via regulating lipid metabolism through decreasing sterol regulatory element binding p (显示 ALT 抗体)rotein (SREBP)-1c expression a (显示 TMPRSS11D 抗体)nd its downst (显示 INS 抗体)ream targeting enzymes such as fatty acid synthase (FAS), HMG-CoA reductase (HMGCR) and acetyl-Coenzyme A carboxylase (ACCalpha).

  2. Genetic ablation of ClC-2 resulted in reduced gastric gland region, reduced parietal cell number, reduced H/K ATPase (显示 ATP4b 抗体), reduced tubulovesicles and reduced stimulated acid secretion.

  3. Data indicate that membrane protein MLC1 is crucial for proper localization of adhesion molecule (显示 NCAM1 抗体) GlialCAM (显示 HEPACAM 抗体) and chloride channel (显示 CLCA1 抗体) ClC-2, and for changing ClC-2 currents.

  4. Loss of ClC-2 is associated with increased development of DSS (显示 PMP22 抗体)-induced colitis.

  5. The PCR data revealed the existence of two astrocytic subpopulations markedly differing in their gene expression levels for inwardly rectifying K+ channels (Kir4.1 (显示 KCNJ10 抗体)), K(2P) channels (TREK-1 (显示 KCNK2 抗体) and TWIK-1 (显示 KCNK1 抗体)) and Cl- channels (ClC2).

  6. ClC-2 channels are required for colonic electroneutral absorption of NaCl and KCl.

  7. permeant Cl(-) ions contribute to V(m)-dependent gating of the broadly distributed ClC-2 Cl() channel.

  8. GABAA (显示 GABRg1 抗体) receptor-mediated synaptic inputs from basket cells were modulated by ClC-2. Our data reveal a previously unknown cell type-specific regulation of intracellular chloride homeostasis in the perisomatic region of hippocampal pyramidal neurons.

  9. ClC-2 reduces barrier function in normal mucosa. Ultrastructural morphology of tight junctions and myosin light chain kinase (显示 MYLK 抗体) appear to be important to the function of ClC-2 in normal mucosa.

  10. these findings raise the possibility that ClC-2 expression plays a subtle neuroprotective role in the aging hippocampus

Pig (Porcine) Chloride Channel 2 (CLCN2) interaction partners

  1. ClC-2-mediated intestinal Cl - secretion restores transepithelial resistance in ischemia-injured intestine.

Human Chloride Channel 2 (CLCN2) interaction partners

  1. The inhibitory effects of ClC-2 knockout on HBVSMC proliferation and motility were associated with inactivation of the Wnt (显示 WNT2 抗体)/beta-catenin (显示 CTNNB1 抗体) signaling pathway, as evidenced by inhibition of beta-catenin (显示 CTNNB1 抗体) phosphorylation and nuclear translocation, and decrease of GSK-3beta phosphorylation and survivin and cyclin D1 (显示 CCND1 抗体) expression.

  2. Leukoencephalopathy-causing CLCN2 mutations impair chloride channel (显示 CLCA1 抗体) gating and trafficking.

  3. ClC-2 mRNA level was significantly increased in patients with non-alcoholic steatohepatitis, which positively correlated with the plasma levels of alanine transaminase (ALT), aspartate transaminase (AST) and insulin (显示 INS 抗体).

  4. The findings show that RGET691 of human ClC-2 (possible binding site) plays an important functional role in fatty acid activation of human ClC-2.

  5. Hyperpolarization activates CLC-2 mainly by driving intracellular anions into the channel pores.

  6. The extracellular domain of GlialCAM (显示 HEPACAM 抗体) is necessary for cell junction targeting and for mediating interactions with itself or with MLC1 and ClC-2.

  7. both ubiquitous (AP-1A) and epithelium-specific (AP-1B) forms of the tetrameric clathrin adaptor AP-1 (显示 FOSB 抗体) are capable of carrying out basolateral sorting of ClC-2.

  8. SPAK (显示 STK39 抗体) and OSR1 (显示 OXSR1 抗体) are powerful negative regulators of the cell volume regulatory Cl- channel ClC-2

  9. Correlation between CLC-2 gene expression and the cytoskeleton in human trabecular meshwork cells.

  10. Our observations substantiate the concept that ClC-2 is involved in brain ion and water homoeostasis

Chloride Channel 2 (CLCN2) 抗原简介

蛋白简介

This gene encodes a voltage-gated chloride channel. The encoded protein is a transmembrane protein that maintains chloride ion homeostasis in various cells. Defects in this gene may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-Chloride Channel 2 (CLCN2) 抗体

  • chloride voltage-gated channel 2 (CLCN2) 抗体
  • chloride channel, voltage-sensitive 2a (clcn2a) 抗体
  • chloride channel protein 2 (EHI_142170) 抗体
  • chloride channel protein 2 (EHI_186860) 抗体
  • chloride channel, voltage-sensitive 2 (Clcn2) 抗体
  • chloride voltage-gated channel 2 (Clcn2) 抗体
  • AL118368 抗体
  • CIC-2 抗体
  • clC-2 抗体
  • Clc2 抗体
  • CLCN2 抗体
  • ECA2 抗体
  • ECA3 抗体
  • EGI3 抗体
  • EGI11 抗体
  • EGMA 抗体
  • EJM6 抗体
  • EJM8 抗体
  • LOC100150892 抗体
  • nmf240 抗体

Protein level used designations for anti-Chloride Channel 2 (CLCN2) 抗体

chloride channel 2 , novel protein similar to vertebrate chloride channel 2 (CLCN2) , chloride channel protein 2 , PKA-activated chloride channel ClC-2G , clC-2

GENE ID SPECIES
704709 Macaca mulatta
100125625 Ovis aries
100150892 Danio rerio
3405494 Entamoeba histolytica HM-1:IMSS
3410767 Entamoeba histolytica HM-1:IMSS
12724 Mus musculus
505569 Bos taurus
100135500 Cavia porcellus
397147 Sus scrofa
1181 Homo sapiens
29232 Rattus norvegicus
488106 Canis lupus familiaris
100009530 Oryctolagus cuniculus
425295 Gallus gallus
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