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Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. 再加上，我们可以发Casein Kinase 2, alpha 1 Polypeptide 蛋白 (21) 和 Casein Kinase 2, alpha 1 Polypeptide 试剂盒 (13)和数多这个蛋白质的别的产品。
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Human Polyclonal CSNK2A1 Primary Antibody for WB - ABIN1944742
Devilat, Carvallo: Structure and sequence of an intronless gene for human casein kinase II-alpha subunit. in FEBS letters 1993
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Human Polyclonal CSNK2A1 Primary Antibody for WB - ABIN1881717
Ahmed, Davis, Hanten, Lambert, McIvor, Goueli: Cloning of cDNAs encoding the alpha and beta subunits of rat casein kinase 2 (CK-2): investigation of molecular regulation of CK-2 by androgens in rat ventral prostate. in Cellular & molecular biology research 1994
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Human Polyclonal CSNK2A1 Primary Antibody for WB - ABIN1944758
Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: Complete sequencing and characterization of 21,243 full-length human cDNAs. ... in Nature genetics 2003
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Human Monoclonal CSNK2A1 Primary Antibody for IF, PLA - ABIN514706
Lin, Hung, Lin, Li, Lee, Li, Chen, Chen, Yang: CK2 inhibitors enhance the radiosensitivity of human non-small cell lung cancer cells through inhibition of stat3 activation. in Cancer biotherapy & radiopharmaceuticals 2011
Casein kinase II, glycogen synthase kinase-3, and Ikaros (显示 IKZF1 抗体) mediated regulation of leukemia has been summarized. (Review)
Our results showcase the potentially valuable functional impact of microRNAs in regulating GG related epilepsy. As CK-2alpha inhibition enhances miR (显示 MLXIP 抗体)-217 expression, disrupting the miR (显示 MLXIP 抗体)-217-CK-2alpha interplay through CK-2alpha inhibitors might represent a novel therapeutic strategies aimed at LEAT.
The results suggest that CK2alpha promotes migration and invasion of clear cell renal cell carcinoma (显示 MOK 抗体) and therefore could serve as a novel prognostic biomarker and molecular therapeutic target in this type of cancer.
The newly designed casein kinase 2 (CK2) Inhibitors were screened on one lung cancer cell line A549, showing low micromolar anti-proliferative activity.
CK2 governs the molecular decision between encephalitogenic TH17 cells and protective Treg cells development.
Data suggest that casein kinase 2 (CK2) inhibition is a promising approach to blocking beta-catenin (显示 CTNNB1 抗体) in MPNST cells, although combinatorial therapies may be required for maximal efficacy.
Results provide evidence that CK2A is critical fro RSV virus replication in human cells.
Vascular smooth muscle protein kinase CK2 inhibition suppresses neointima formation via a proline-rich homeodomain-dependent mechanism.
we have identified kinases, particularly CK2, associated with the autocrine malignant cell network that may play a central role in sustaining the cytokine network and/or mediating its effects in ovarian cancer.
CK2 and AKT (显示 AKT1 抗体) display a high degree of cross-regulation of their respective functions, both directly, through physical interaction and phosphorylation, and indirectly, through an intense cross-talk of key downstream effectors, ultimately leading to sustained AKT (显示 AKT1 抗体) activation. (Review)
To clarify the control mechanism of the catalytic activity of casein kinase 2 (CK2) during early embryonic development in the silkworm, Bombyx mori, attempted an in-vitro functional analysis by using the recombinant alpha and beta subunits of B. mori CK2
identify the the ZmeIF5A serine residues phosphorylated by CK2
analysis of free energy differences of binding of adenosine triphosphate (ATP) and guanine triphosphate (GTP (显示 AK3 抗体)) to the protein kinase CK2
The regulatory subunit of protein kinase CK2 is identified as a novel intracellular partner of AdipoR1 and CK2 is shown to be an effector molecule in adiponectin signaling.
CK2alpha-4 is a splicing variant of maize protein kinase CK2, and may function as a negative regulator of other CK2s.
these data suggest that Fcgamma receptor/reactive oxygen species/CK2alpha is a key inducer of NF-kappaB (显示 NFKB1 抗体) activation in airway epithelial cells in a murine model of asthma
Data (including data from studies using knockout mice) suggest that Brg1 (显示 SMARCA4 抗体) is phosphorylated by casein kinase 2 (Ck2; Ck2alpha1 and Ck2alpha-prime are catalytic subunits) in proliferating skeletal myoblasts; Brg1 (显示 SMARCA4 抗体) is catalytic subunit of SWI (显示 SMARCA1 抗体)/SNF (显示 SNRPA 抗体) chromatin-remodeling enzymes; Ck2-mediated phosphorylation of Brg1 (显示 SMARCA4 抗体) appears to regulate myoblast proliferation. (Brg1 (显示 SMARCA4 抗体) = Brahma (显示 SMARCA2 抗体)-related gene 1 protein)
Casein kinase 2 plays a central role in striatal physiology and in severity of l-DOPA-induced dyskinesia.
Casein kinase 1 (显示 CSNK1A1 抗体) (alpha, delta and epsilon) localize at the spindle poles, but may not be essential for mammalian oocyte meiotic progression.
These data support a model in which activated Akt (显示 AKT1 抗体) enhances rRNA synthesis both by preventing TIF-IA (显示 RRN3 抗体) degradation and phosphorylating CK2alpha, which in turn phosphorylates TIF-IA (显示 RRN3 抗体).
receptor beta and its domains interact with casein kinase 2, phosphokinase C, and N-myristoylation sites of mitochondrial and nuclear proteins in mouse brain
TNP1 is a newly identified binding partner of the alpha-subunit of casein kinase 2.
Casein kinase II has a role in phosphorylation of NF-kappaB (显示 NFKB1 抗体) p65 (显示 NFkBP65 抗体) subunit enhancement of inducible nitric-oxide synthase (显示 NOS2 抗体) gene transcription
CK2 selectively phosphorylates MKP3 (显示 DUSP6 抗体), suggesting cross-regulation between CK2alpha and MKP3 (显示 DUSP6 抗体), as well as a modulation of ERK2-MAPK (显示 MAPK1 抗体) signaling by CK2alpha via MKP3 (显示 DUSP6 抗体)
In cultured hippocampal neurons, the capacity of Nerve Growth Factor to promote axon elongation is mostly mediated by p75NTR, and the activation of this pathway leads to the inactivation of GSK-3beta.
Involvement of ubiquitous protein kinase CK2 in angiogenesis. Naturally derived CK2 inhibitors may be useful for treatment of proliferative retinopathies. (Protein kinase CK2)
Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. While this gene is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for this gene.
CK II alpha 3
, CK2 catalytic subunit alpha
, casein kinase II alpha 1 polypeptide pseudogene
, casein kinase II alpha 1 subunit
, casein kinase II subunit alpha
, protein kinase CK2
, casein kinase 2 alpha subunit
, ck2 alpha
, casein kinase 2, alpha 1 polypeptide
, casein kinase 2 protein catalytic subunit
, casein kinase II subunit alpha-like
, CK II alpha
, casein kinase 2, alpha subunit
, CK II
, casein kinase II alpha subunit
, CK2 alpha subunit
, casein kinase2 subunit alpha
, casein protein kinase subunit alpha
, Casein kinase II alpha subunit
, casein kinase II, alpha 1 polypeptide
, casein kinase II, alpha 1 related sequence 4
, Casein kinase II subunit alpha'
, alpha subunit of casein kinase II